Literature Review

The global need for paediatric palliative care: the evolution of serious health-related suffering in children aged 0-19 years from 1990 to 2023 The Lancet - Child & Adolescent Health; by Julia Downing, Felicia Marie Knaul, Xiaoxiao Jiang Kwete, Héctor Arreola-Ornelas, Nickhill Bhakta, William E Rosa, Lukas Radbruch, Julia Ambler, Stephen R Connor, Jinfeng Ding, Megan Doherty, Rui Gong, Richard Hain, Rut Kiman, Eric L Krakauer, Michael J McNeil, Oscar Méndez-Carniado, Marina Morais, Mary Ann Muckaden, Tania Pastrana, Marianne Phillips, Hongliang Tao, Michael Touchton, Valentina Vargas Enciso, Paul Vila, Afsan Bhadelia; online ahead of print March 2026 Our findings underscore the crucial need to expand access to high-quality palliative care services for children and adolescents, particularly in low-income and middle-income countries (LMICs). Our results also highlight the shift from decedent to non-decedent care needs associated with the substantial morbidity experienced by those living with their disease. Specific health-system policies to respond to the need for increased and higher-quality paediatric palliative care, especially interventions and medicines essential to address the unique palliative care needs of children, must be adequately funded to effectively reduce the avoidable burden of serious health-related suffering (SHS) among children.

[China] Progress in research on alleviating the symptoms associated with advanced cancer using Traditional Chinese MedicinePain Research & Management; by Chunmeng Jiao, Ting Zhang, Yachen Yang, Ruofan Zhang, Wenbo Liu, Yanqing Wang, Lei Huang; 1/26Advanced cancer continues to pose a substantial global challenge, with complex symptom burdens and limited therapeutic options. Traditional Chinese Medicine (TCM), grounded in holistic theory and the principles of syndrome differentiation, employs interventions such as herbal medicine, acupuncture, moxibustion, and acupoint‐based therapies to address both the malignancy and the patient’s overall functional status. Emerging evidence indicates that TCM may alleviate symptom clusters associated with advanced cancer, enhance quality of life, and potentially contribute to improved survival outcomes. This review synthesizes findings from the past decade on the role of TCM in advanced cancer care, with a focus on herbal decoctions, Chinese herbal injections, acupuncture—either alone or in combination with herbal therapy—moxibustion with adjuvant medication, and other external TCM modalities. Evidence is examined regarding their effects on cancer‐related pain, fatigue, gastrointestinal dysfunction, chemotherapy‐ and radiotherapy‐induced toxicities, and immune modulation.

[Global] UCLA report reveals a significant global palliative care gap among children  UCLA Health, Los Angeles, CA; by University of California, Los Angeles (UCLA) - Health Sciences; 2/10/26 Nearly all the world’s 10.6 million children experiencing serious health-related suffering (SHS) live in low- and middle-income countries with little to no access to palliative care specialized care for their illness, according to a comprehensive new report published in The Lancet Child & Adolescent Health. ... The findings reveal a dramatic shift: most children in need of palliative care now live longer with severe, chronic illness, fundamentally changing the type of services needed and extending the duration of these services. ...

[UK] The effects of music interventions on behavioural and psychological symptoms in older adults with dementia: Systematic reviewAdvances in Mental Health; by Motunrayo A. Akinboye, Benjamin O. Ajibade; 12/25Dementia, affecting over 55 million people globally, often presents with behavioural and psychological symptoms (BPSDs) such as agitation, depression, and anxiety. Pharmacological treatments can lead to adverse effects, highlighting theneed for safer, non-drug alternatives like music interventions. Findings show that music interventions significantly alleviated symptoms such as depression, anxiety, and agitation. Both active (e.g., singing, playing instruments) andreceptive (e.g., listening) music therapy formats were effective, with sessions ranging from 20–90 minutes. Interventions were most successful when personalized and culturally tailored.

[Worldwide] End-of-life care statistics by care, conditions and illness (2026) Market.us Media; by Samruddhi Yardi; 2/2/26 Each year, an estimated 56.8 million people, including 25.7 million in the last year of life, are in need of palliative care. Worldwide, only about 14% of people who need palliative care currently receive it. ... As society continues to grapple with evolving views on life and death, the commitment to compassionate, personalized, and respectful end-of-life care remains paramount. Embracing this philosophy ensures that every individual is allowed a dignified and meaningful conclusion to their life’s journey.

[Australia] Cancer and dementia incidence are strongly correlated worldwide: Evidence from cross-national regression analysesFuture Science OA; by Wenpeng You, Brendon J Coventry, Maciej Henneberg; 12/25Cancer and dementia are two major health problems affecting millions of people around the world. Countries with higher cancer rates almost always have higher dementia rates. Even after we accounted for income, life expectancy, and other social factors, cancer remained one of the strongest predictors of dementia. These findings suggest that cancer and dementia share many of the same underlying causes, such as aging, chronic inflammation, lifestyle habits, and changes that come with economic development. Understanding these shared patterns can help countries plan for future healthcare needs.

Sanofi Collective - Foundation S stands behind transformative children's palliative care project in Kenya Global Treehouse Foundation; Press Release; 1/27/26 A significant grant from the Foundation S - the Sanofi Collective will enable a transformative three-year project delivering comprehensive grief and bereavement care to families affected by childhood cancer in Kenya. This is about more than funding: it’s about ensuring families are seen, supported and not left to navigate their most challenging moments alone. Foundation S’s investment is a significant milestone in integrating grief and social-emotional support into healthcare systems - an area too often overlooked, yet essential to the dignity and well-being of children and those who love them.

[United Kingdom] Hospice to support additional 1,000 patients BBC News; by Greig Watson; 1/25/26 A service to look after terminally ill people is to be expanded across much of Nottinghamshire after a new contract was awarded. Newark-based Beaumond House Hospice Care will lead on the creation of a new End of Life Referral Hub and make its Hospice at Home service available across Newark, Sherwood, Mansfield, Ashfield and Bassetlaw. The service is currently provided to about 200 patients across Newark and Sherwood but from April 2026 it will care for an additional 1,000 patients a year in their place of choice. ... Macmillan Cancer Support's End-of-Life Care Fund is providing the £1.8m of funding to support the expansion.Editor's Note: Recent hospice coverage from the United Kingdom has largely focused on service reductions. This announcement offers welcome news, signaling expanded access to end-of-life care for more patients. We hope this growth is accompanied by continued commitment to high-quality, person-centered care for patients and families.

[Italy] End of life with psylocibin: Research, data and experienceEmerging Trends in Drugs, Addictions, and Health; by T. Re, A. Metastasio; 12/25Throughout history, mushrooms have served as a bridge for ancient populations, guiding human beings from earthly life to the "Beyond" and allowing them to "taste" this passage during their lifetime, thereby alleviating the fear of death. Recent scientific research has revealed that these ancient practices are supported by research done by leading world universities showing the effectiveness of psilocybin mushrooms in addressing fear of death, anxiety, and existential stress. The experience of guiding a person across the bridge between life and death raises intriguing questions about the nature of consciousness, the potential for communication in "non-ordinary states of consciousness" between different realms of nature, and the possibility of transcending space and time, thereby creating a new experience and continuity between life and death. Although we advocate for a wider and more accessible of use of psylocibin in the end of life we believe that more studies are necessary to identify the subjects that would benefit the most from this practice.

[Uganda] This hospice has a bold new mission: saving lives Alabama Public Radio / NPR; by Joanne Cavanaugh Simpson, Brian Simpson; 1/16/26 Deborah Nantenza learned about cervical cancer screening at a hospital in eastern Uganda, a rural region where early diagnosis is rare. ... The cancer screening, education and treatment were led by a hospice — an institution traditionally limited to easing the pain of the dying. The team at Rays of Hope Hospice Jinja in Uganda had long wanted to do more. Even with liquid morphine and other pain medications the hospice provided to ease symptoms, women with cervical cancer "didn't just die a normal death. They died after suffering, suffering," says Sylvia Nakami, executive director of the 20-year-old nonprofit.

[United Kingdom] One in five hospice beds closed, report warns in end of life care crisis Express - Health and Social Affairs; by Lucy Johnston; 1/10/26 Almost one in five hospice beds in England is now closed or standing empty, despite growing demand for end-of-life care, a study by Oxford University researchers has found. The analysis exposes a deepening funding crisis in the hospice sector - which its authors have described as “a national scandal.” ... [Oxford University professors describe that] ... increasing numbers of frail and elderly patients are dying “in pain, alone, often hungry and dehydrated,” while others are being admitted to hospital in emergency situations, adding pressure to already stretched NHS services.