Literature Review

All posts tagged with “Clinical News | Pain Management.”



Why are more older people dying after falls?

10/08/25 at 02:00 AM

Why are more older people dying after falls? KFF Health News; by Paula Span; 9/30/25 ... Public health experts have warned of the perils of falls for older people for decades. In 2023, the most recent year of data from the Centers for Disease Control and Prevention, more than 41,000 Americans over 65 died from falls, an opinion article in JAMA Health Forum pointed out last month. More startling than that figure, though, was another statistic: Fall-related mortality among older adults has been climbing sharply. ... [Death] rates from fall injuries among Americans over 65 had more than tripled over the past 30 years. Among those over 85, the cohort at highest risk, death rates from falls jumped to 339 per 100,000 in 2023, from 92 per 100,000 in 1990.  ...

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Medicaid coverage policy variations for chronic pain and opioid use disorder treatment

10/04/25 at 03:20 AM

Medicaid coverage policy variations for chronic pain and opioid use disorder treatmentJAMA Network Open; by Meredith C. B. Adams, Seth M. Eller, Cara McDonnell, Sarjona Sritharan, Rishika Chikoti, Amaar Alwani, Elaine L. Hill, Robert W. Hurley, ; 8/25Co-occurring chronic pain and opioid use disorder (OUD) are associated with a high disease burden for the patient, requiring comprehensive treatment approaches, yet Medicaid benefit structures for evidence-based therapies vary substantially across states. Our systematic economic evaluation reveals both promising developments and persistent challenges in Medicaid coverage for treatment of co-occurring OUD and chronic pain. Universal coverage of fundamental medications and basic interventional procedures provides a foundation for care, but varying implementation approaches create a complex landscape requiring further investigation.

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Initiation of pregabalin vs gabapentin and development of heart failure

09/27/25 at 03:20 AM

Initiation of pregabalin vs gabapentin and development of heart failureJAMA Network Open; by Elizabeth E. Park, Laura L. Daniel, Alyson L. Dickson, Meghan Corriere, Puran Nepal, Kathi Hall, W. Dale Plummer, William D. Dupont, Katherine T. Murray, C. Michael Stein, Wayne A. Ray, Cecilia P. Chung; 8/25Both pregabalin and gabapentin are common nonopioid medications used to treat chronic pain, which affects up to 30% of patients. Because pregabalin has greater potency than gabapentin in binding to the α2δ subunit of the L-type calcium channel, pregabalin may be associated with an increased risk for heart failure (HF). The findings suggest that pregabalin should be prescribed with caution in older patients with noncancer chronic pain.

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The role of the palliative medicine and supportive oncology APP

09/23/25 at 03:00 AM

The role of the palliative medicine and supportive oncology APP Oncology Nursing News; by Antonia Corrigan, MSN, ANP-C; 9/22/25 ... A cancer diagnosis can bring an avalanche of psychosocial and physical obstacles for patients to navigate. ... Advanced practice providers (APPs) are key in providing quality supportive care. ... The American Society of Clinical Oncology (ASCO) guidelines recommend that patients with cancer be referred to interdisciplinary palliative care teams within 8 weeks of diagnosis. Early palliative referral benefits patients with high symptom burden, both physical and psychosocial, and enhances caregiver support. 

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Wound care at Sheridan VA gives 95-year-old Veteran a second chance: Veteran removed from hospice care at Sheridan VA after wounds heal

09/17/25 at 02:30 AM

Wound care at Sheridan VA gives 95-year-old Veteran a second chance: Veteran removed from hospice care at Sheridan VA after wounds heal VA News; by Jesus Flores; 9/12/25 When 95-year-old Air Force Veteran Roy Clifton arrived at Sheridan VA Medical Center (SVAMC) in March 2025, he thought he didn’t have much time left. “I had a bone infection in both feet and could barely walk,” he said. “Then I had a fall that caused a bleed in my brain. That’s when I decided to call it quits and go to hospice.” ... [Scroll ahead to this hospice's expert wound care.] Although both feet had exposed bones, and the injuries looked and smelled bad, Clifton’s body was healing. ... Clifton’s condition improved so much, he was taken off hospice care. “It made me feel great to survive hospice,” he said, smiling. “They’re all great. The staff took good care of me.”

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Reconsidering neuraxial analgesia at end of life: Clinical, ethical, and socioeconomic perspectives

09/06/25 at 03:10 AM

Reconsidering neuraxial analgesia at end of life: Clinical, ethical, and socioeconomic perspectivesInterventional Pain Medicine; Sanjeet Narang , Jason Yong , David Hao, 9/25Pain is one of the most prevalent and distressing symptoms experienced by patients nearing end of life, particularly among those with cancer. While systemic opioids are the mainstay of treatment, their limitations necessitate consideration of alternative strategies. Neuraxial analgesia, including epidural and intrathecal drug delivery systems, offers targeted pain relief with reduced systemic burden. Yet despite supportive data, these interventions remain underutilized due to clinical, ethical, logistical, and socioeconomic barriers. This article examines the complex decision-making involved in offering neuraxial analgesia at the end of life, weighing risks and benefits, shifting patient goals, and the challenges of care coordination.

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[Canada] Simplifying palliative symptom management: Elastomeric infusions in hospice and home care

08/30/25 at 03:05 AM

[Canada] Simplifying palliative symptom management: Elastomeric infusions in hospice and home careBritish Journal of Nursing; by Vincetic Bozidar, Natalie Wm Hertzman, Daphne Broadhurst; 7/25Palliative care patients often require frequent, resource-intensive, intermittent subcutaneous injections or complex infusion pumps for end-of-life symptom management. Our findings suggest that continuous subcutaneous infusions via elastomeric infusion pumps offer a promising and feasible approach to end-of-life symptom management in hospice and home care. Elastomeric infusions may enhance simplicity, acceptability, safety, efficacy, and efficiency of care, compared to traditional routine subcutaneous injections.

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Social relationships and end-of-life quality among older adults in the United States: The impacts of marital, kinship, and network ties

08/16/25 at 03:20 AM

Social relationships and end-of-life quality among older adults in the United States: The impacts of marital, kinship, and network ties The Journals of Gerontology; by Kafayat Mahmoud, Deborah Carr; 7/25We examine marital status differences in recent decedents’ end-of-life care and gender differences therein, and the role of other social ties (children, siblings, network members) in influencing the quality of end-of-life care. Divorced decedents fared poorly on multiple outcomes, being less likely than married or widowed persons to receive excellent care and to have personal care needs met. Divorced and widowed decedents were less likely to receive respectful treatment relative to married decedents. We found no significant gender differences in these patterns. Persons with more siblings and network members had superior pain management. Hospital patient advocates could also aid those who lack close kin at the end of life.

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Implementation of the Pressure Injury Prevention Care Bundle at a home based hospice program: A quality improvement project

08/13/25 at 03:00 AM

Implementation of the Pressure Injury Prevention Care Bundle at a home based hospice program: A quality improvement project The Texas Medical Center (TMC) Library Health Sciences Resource Center; by Adaeze U. Amechi-fannin; 8/11/25 Pressure injuries remain a common and serious problem in hospice care, especially among patients who are immobile or confined to bed. Although effective prevention methods are known, inconsistent use of these methods, limited caregiver training, and poor documentation have continued to prevent success in many hospice settings. These wounds cause pain, increase infection risk, and reduce quality of life, making prevention especially important in end-of-life care. ... This project demonstrates that combining structured training, evidence-based care steps, and attention to individual patient needs can successfully reduce pressure injuries in home hospice environments.

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Caring for every breath: Carolina Caring Advanced Lung Care Program launched August 1st

08/11/25 at 03:00 AM

Caring for every breath: Carolina Caring Advanced Lung Care Program launched August 1st Carolina Caring, Newton, NC; Press Release; 8/8/25 A specialized lung care program providing care for complex respiratory conditions will bring needed comfort and support to many individuals. Launched on August 1st, 2025, Carolina Caring’s Advanced Lung Care Program helps patients receive the personalized care they need for their advanced respiratory illness at end of life, while remaining comfortably at home—leading to a reduction of hospitalizations and improved quality of life for patients and their families. 

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Study reveals how medication side effects can lead to dangerous medication cycles in adults 65+

08/04/25 at 03:00 AM

Study reveals how medication side effects can lead to dangerous medication cycles in adults 65+ McKnights Long-Term Care News; by Donna Shryer; 7/31/25 When doctors treat drug side effects as new illnesses, older adults may be prescribed even more medications — a cycle known as a “prescribing cascade.” A new study says this prescribing cycle can increase the risk of harm. A prescribing cascade example cited in the research involves older patients taking calcium channel blockers for blood pressure control, which can cause ankle swelling side effects. Instead of first adjusting the blood pressure drug, some doctors immediately prescribe a diuretic to reduce the swelling — which for some, can create an unnecessary drug pair.

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The treatment of chemotherapy-induced peripheral neuropathy: A review of current management options and a potential role for scrambler therapy

08/02/25 at 03:45 AM

The treatment of chemotherapy-induced peripheral neuropathy: A review of current management options and a potential role for scrambler therapyFrontiers in Pain Research; by Hassan Aboumerhi, Henry Vucetic, Andrew Gruenzel, Bahar Moftakhar, Mona Gupta, Santosh K Rao, Michael D Staudt; 7/25Chemotherapy-induced peripheral neuropathy (CIPN) presents a growing medical and financial burden on patients and the healthcare system alike. This has been treated with conservative and interventional care limited by efficacy, side effects, and lack of coverage. As such, there is an unmet treatment need for effective non-invasive or minimally invasive therapies for the treatment of CIPN. Scrambler therapy (ST) is a peripheral, non-invasive neuromodulation technique, which uses transcutaneous electrical stimulation to modulate pain signals. ST has shown mixed results in clinical trials; while some patients report symptom relief, more robust evidence is required before it can be widely recommended.

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Evaluating the role of palliative care in emergency department opioid use among advanced cancer patients

08/02/25 at 03:20 AM

Evaluating the role of palliative care in emergency department opioid use among advanced cancer patientsSupportive Care in Cancer; by Joel Nortey, Shiyun Zhu, Andrew Lynch, Hannah Whitehead, Nirmala Ramalingam, Raymond Liu; 7/25 Patients with advanced cancer often experience severe symptoms that significantly impact their quality of life, leading to frequent emergency department [ED] visits for pain management. These visits not only diminish patient quality of life, but also impose substantial costs on the healthcare system. Our study highlights the significant role that PC can play in reducing ED utilization for pain management needs among advanced cancer patients, improving quality of life and alleviating healthcare burdens.

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Regional anesthesia for hip fracture surgery in older adults: A retrospective comparison of outcomes using ACS NSQIP data

07/26/25 at 03:45 AM

Regional anesthesia for hip fracture surgery in older adults: A retrospective comparison of outcomes using ACS NSQIP dataGeriatric Orthopaedic Surgery & Rehabilitation; Arissa M. Torrie, MD, MHS; Gerard P. Slobogean, MD, MPH; Rachel Johnson, MD; Ron E. Samet, MD; Samuel M. Galvagno, DO, PhD; Robert V. O’Toole, MD; Nathan N. O’Hara, PhD, MHA; 6/25Surgical fixation of hip fractures in older adults is associated with significant morbidity and mortality. This study found that regional anesthesia, presumably using peripheral nerve block techniques, may offer advantages beyond pain control, with potential protective benefits in high-risk hip fracture patients. Future clinical trials should examine peripheral nerve block benefits beyond pain management, identify mechanisms of action, determine optimal techniques for different risk profiles, and assess long-term outcomes. By combining the insights from this study with carefully designed future research, researchers can work towards developing more effective, patient-centered approaches to anesthesia for older adults undergoing surgical fixation of hip fractures.

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New curriculum - Enhance your pain management skills

07/23/25 at 03:10 AM

New curriculum - Enhance your pain management skillsCAPC email; 7/16/25Pain is one of the most common and distressing symptoms for patients living with a serious illness, significantly impacting quality of life. CAPC’s new Pain Management: Relieving Suffering and Reducing Risk unit combines our previous two pain units into one streamlined, comprehensive training, incorporating the latest best practices in evidence-based pain management.

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HOPE Tool Anxiety, Part II: From planning to practice

07/02/25 at 03:00 AM

HOPE Tool Anxiety, Part II: From planning to practice Teleios Collaborative Network (TCN); podcast by Melissa Calkins; 6/30/25The countdown has begun. With October 1 on the horizon, hospice teams across the country are deep into training and testing—but preparation alone won’t guarantee success. The shift to HOPE isn’t just operational; it’s cultural. And real readiness goes far beyond timelines and task completion. It demands that every clinician, across every shift and care setting, understands what’s changing and feels confident in how to respond. This is the critical moment when planning must translate into practice—because once HOPE is live, the margin for error disappears.

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Online dialectical behavioral therapy for emotion dysregulation in people with chronic pain-A randomized clinical trial

06/07/25 at 03:45 AM

Online dialectical behavioral therapy for emotion dysregulation in people with chronic pain-A randomized clinical trialJAMA Network Open; Nell Norman-Nott, BPsychSc; Nancy E. Briggs, PhD; Negin Hesam-Shariati, PhD; Chelsey R. Wilks, PhD; Jessica Schroeder, PhD; Ashish D. Diwan, MD, PhD; Jina Suh, PhD; Jill M. Newby, PhD; Toby Newton-John, PhD; Yann Quidé, PhD; James H. McAuley, PhD; Sylvia M. Gustin, PhD; 5/25Chronic pain, defined as pain persisting beyond 3 months,1 affects 20% to 30% of the population. Beyond its sensory experience, chronic pain is an intrinsically emotional experience associated with heightened negative emotions, including anger, worry, and low mood, alongside a diminished capacity to regulate emotions. Dysregulated emotions contribute to comorbid psychological disorders; symptoms of anxiety and depression, which are present in 50% to 80% of people with chronic pain; and worsening pain intensity. One emotion regulation–focused intervention being adapted for chronic pain is dialectical behavioral therapy (DBT). In DBT skills training, emotion regulation is improved by encouraging emotion recognition, emotion expression, and reaction evaluation. Results of small in-person trials of DBT for people with chronic pain show promise to improve emotion dysregulation, depression, anxiety, and pain intensity.

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MLN Fact Sheet: Creating an effective hospice Plan of Care

05/30/25 at 03:00 AM

MLN Fact Sheet: Creating an efffective Hospice Plan of CareCenters for Medicare & Medicaid Services, Medicare Learning Network (MLN); 5/10/25 The hospice plan of care (POC) maps out needs and services given to a Medicare patient facing a terminal illness, as well as the patient’s family or caregiver. CMS data shows that some hospice POCs are incomplete or not followed correctly. This fact sheet educates on creating and coordinating successful hospice POCs. The primary goal of hospice care is to meet the holistic needs of an individual and their caregiver and family when curative care is no longer an option. To support this goal:

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A practice model for palliative radiotherapy

05/24/25 at 03:45 AM

A practice model for palliative radiotherapyCureus; Alina Zheng, Alec Zheng, Alan Zheng, Xiaodong Wu, Beatriz Amendola; 5/25Despite well-recognized challenges in implementing palliative radiation therapy (PRT), progress remains slow, and conventional approaches have yielded limited success. A specialized certification track within radiation oncology residency programs is proposed, enabling palliative care physicians to obtain limited PRT licenses under the supervision of fully licensed radiation oncologists. Dedicated PRT facilities-affiliated with comprehensive radiation therapy centers (CRTCs) and integrated into hospice settings-will enhance accessibility by reducing logistical and financial burdens. These facilities will utilize cost-effective infrastructure, including refurbished linear accelerators, modular construction, and remote physics and dosimetry support, ensuring operational costs remain significantly lower than those of conventional radiotherapy centers. Systematic studies with a PRT-oriented mindset should establish PRT-specific treatment recommendations and recommendations, moving away from conventional radiation therapy protocols. While requiring initial investment and regulatory adjustments, it has the potential to improve end-of-life care for terminally ill cancer patients, ensuring greater dignity and comfort while establishing a robust foundation for future reimbursement models.

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The 2016 CDC Opioid Guideline and analgesic prescribing patterns in older adults with cancer

05/24/25 at 03:05 AM

The 2016 CDC Opioid Guideline and analgesic prescribing patterns in older adults with cancerJAMA Network Open; Rebecca Rodin, MD, MSc; Lihua Li, PhD; Karen McKendrick, MPH; Krista Harrison, PhD; Lauren J. Hunt, PhD, RN; Ulrike Muench, PhD, RN; Cardinale B. Smith, MD, PhD; Melissa D. Aldridge, PhD, MPH, MBA; R. Sean Morrison, MD; 5/25In 2016, the Centers for Disease Control and Prevention (CDC) published guidelines cautioning against prescribing opioids for chronic noncancer pain. In this cohort study of older adults with cancer, the 2016 CDC guideline was associated with a decline in first-line opioids while less-safe tramadol and less-effective gabapentinoid prescribing continued to rise. Further revision of the recent 2022 CDC guideline and oncology pain management guidelines may be needed to help address these potentially inappropriate analgesic shifts.

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‘Marathon’ effort to refine end-of-life wound coding runs on

05/23/25 at 03:00 AM

‘Marathon’ effort to refine end-of-life wound coding runs on McKnights Long-Term Care News; by Kimberly Marselas; 5/28/25 Two key wound care groups are finalizing a proposal for new codes that would help skilled nursing providers avoid newly created diagnoses gaps for end-of-life skin breakdown that could lead to missed reimbursement and potential liability risks. The push comes a year and a half after nursing homes won the right to stop coding wounds that occur as part of dying as pressure injuries, which can hurt their quality ratings. But they also lost any way to code or acknowledge treatment of such skin failure in the Minimum Data Set. ...

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[Brazil] Music therapy in modulating pain in palliative care patients: A systematic review and meta-analysis

04/26/25 at 03:00 AM

[Brazil] Music therapy in modulating pain in palliative care patients: A systematic review and meta-analysisBritish Journal of Music Therapy; Suellen Fernanda Pinheiro Hammuod, Fernada Gonzalez Santos, Lidiane da Costa Fonseca, Elaine Kakuta, Renata Verão Brito, Karolayne Silva Souza, Eduardo Henrique Loreti; 3/25 Music therapy is an intervention that uses music for therapeutic purposes, helping to preserve mental, physical, and emotional health. Its use in the care of terminally ill patients can assist in managing pain, fatigue, quality of life (QoL), anxiety, and depression. This study aimed to analyze the effects of music therapy on pain in individuals receiving palliative care. Music therapy showed effectiveness in improving pain in patients receiving palliative care ... The effectiveness of music therapy on QoL remains debatable.

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CMS releases HOPE Guidance Manual (V. 1.01) and Tables

04/25/25 at 03:00 AM

CMS releases HOPE Guidance Manual (V. 1.01) and TablesCenters for Medicare and Medicaid Services (CMS); by CMS; 4/22/25On April 22, 2025, CMS released the HOPE Guidance Manual (V. 1.01) and connected tables. Providers can use v1.01 for HOPE planning, as this is considered final before HOPE implementation. Also note that earlier this month, the final HOPE data specs have also been released, helping software developers to finalize their HOPE software for testing in the coming months.

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Prevention of opioid misuse and abuse through effective pain management in patients with chronic pain: An umbrella systematic review

04/19/25 at 03:20 AM

Prevention of opioid misuse and abuse through effective pain management in patients with chronic pain: An umbrella systematic reviewCureus: Sana Sultana, Safeera Khan; 3/25Chronic pain is a condition that affects physical well-being as well as emotional well-being, has mental impacts on patients, and diminishes their quality of life. There is also growing evidence that opioids have only limited effectiveness in the management of CNCP [chronic non-cancer pain], and the increased availability of prescription opioids has contributed to an increase in opioid addiction cases and overdose deaths. This review was conducted to determine if adequate pain management would decrease opioid use and prevent misuse. We discussed the different pain management methods in the paper, including the different pharmacotherapy options, nerve blocks, and spinal cord stimulation. We also talk about multidisciplinary treatment with the involvement of various departments (physician, pharmacy for pill counting, physical therapy, psychological care, etc.) in managing pain; good outcomes were observed with improvement in function.

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Palliative care and advanced cardiovascular disease in adults: Not just end-of-life care: A scientific statement from the American Heart Association

04/18/25 at 03:00 AM

Palliative care and advanced cardiovascular disease in adults: Not just end-of-life care: A scientific statement from the American Heart Association AHAIASA Journals - American Heart Association; by Lucinda J. Graven, PhD, APRN, FAHA, Lisa Kitko, PhD, RN, FAHA, Martha Abshire Saylor, PhD, MSN, BA, RN, Larry Allen, MD, MHS, FAHA, Angela Durante, PhD, RN, Lorraine S. Evangelista, PhD, RN, CNS, WAN, FAHA, Amy Fiedler, MD, James Kirkpatrick, MD, Lakeisha Mixon, MSW, and Rachel Wells, PhD, MSN, BA on behalf of the American Heart Association Complex Cardiovascular Nursing Care Science Committee of the Council on Cardiovascular and Stroke Nursing; and Council on Cardiovascular Surgery and Anesthesia; 4/17/25  ... This scientific statement (1) discusses the application of effective communication, shared decision-making, age-friendly care, and advance care planning in advanced cardiovascular disease palliative care; (2) provides a summary of recent evidence related to palliative care and symptom management, quality of life, spiritual and psychological support, and bereavement support in individuals with advanced cardiovascular disease and their care partners; (3) discusses issues involving diversity, equity, and inclusion in cardiovascular disease palliative care; (4) highlights the ethical and legal concerns surrounding palliative care and implanted cardiac devices; and (5) provides strategies for palliative care engagement in adults with advanced cardiovascular disease for the care team.

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