Literature Review

All posts tagged with “Clinical News | Pharmacy & Medication News.”



Chicago area nurse gets 2 years in prison for stealing morphine from sick patients

04/08/24 at 03:00 AM

Chicago area nurse gets 2 years in prison for stealing morphine from sick patientsCBS News TV 2, Chicago; by Acacia Hernandez; 4/4/24A northwest suburban nurse was sentenced in court on Thursday to two years in federal prison for stealing morphine from her patients, some of whom were terminally ill. Sarah Diamond, 31, of Woodstock, was accused of targeting the most vulnerable, including hospice patients living out their final days. In 2021, she removed liquid morphine from bottles that had been prescribed to at least five hospice patients and replaced it with saline. Prosecutors said she took the medication for her own personal use.

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Cancer patients often want ‘one more round.’ Should doctors say no?

04/02/24 at 03:00 AM

Cancer patients often want ‘one more round.’ Should doctors say no? The Washington Post, by Mikkael A. Sekeres, MD; 3/31/24 My patient was in his early 30s and his leukemia had returned again following yet another round of treatment. He was a poster child for the recently reported rise in cancer rates in the young, and had just asked me what chemotherapy cocktail I could devise for him next, to try to rid him of his cancer. I hesitated before answering. Oncologists are notorious for always being willing to recommend to our patients one more course of treatment, even when the chances of success are negligible.  

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Expanding the use of continuous sedation until death and physician-assisted suicide

03/29/24 at 03:00 AM

Expanding the use of continuous sedation until death and physician-assisted suicide  The Journal of Medicine & Philosophy: A Forum for Bioethics and Philosophy of Medicine; by Samuel H Lipuma and Joesph P Demarco; 3/27/24 The controversy over the equivalence of continuous sedation until death (CSD) and physician-assisted suicide/euthanasia (PAS/E) provides an opportunity to focus on a significant extended use of CSD. 

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Antibiotics in end-of-life care

03/29/24 at 03:00 AM

Antibiotics in end-of-life care NEJM Journal Watch, by Abigail Zuger, MD; 3/27/24Antibiotics often are considered to be among the gentler and more comfort-oriented interventions in end-of-life care, certainly far less aggressive than intubation or last-ditch surgery. ... Still, antibiotics do entail their own costs in the form of toxicities and need for intravenous access, and liberal antibiotic use reliably worsens institutional and community drug-resistance profiles. ... A new review was written for infectious disease consultants but contains specific suggestions that should interest both generalists and other subspecialists caring for dying patients. 

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Nurse arrested after morphine, other stolen medical drugs seized in Owensboro

03/28/24 at 03:00 AM

Nurse arrested after morphine, other stolen medical drugs seized in Owensboro14 News WFIE, by Aaron Chatman; 3/26/24 Eight suspects were arrested and facing numerous charges after a massive drug bust in Owensboro. That’s according to the Daviess County Sheriff’s Office, who says they opened an investigation after receiving dozens of tips about a drug trafficking operation at the home of Pamela Bartimus. Deputies say Bartimus was an employee of Hospice & Palliative Care of Western Kentucky and had been stealing medication at her job.

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Partners In Care sets sights on service diversification, hospice-pharmacy partnership

03/26/24 at 03:00 AM

Partners In Care sets sights on service diversification, hospice-pharmacy partnership Hospice News, by Jim Parker; 3/22/24 Hospice providers need to evolve with their changing patient populations and the larger health care system, according to Greg Hagfors, CEO of Partners In Care. The Oregon-based hospice, palliative care and home health provider recently celebrated the 45th anniversary of its founding, which preceded the establishment of the Medicare Hospice Benefit. ... Hospice News recently spoke with Hagfors about the ways the industry has changed since Partners In Care came on the scene — and how it is moving towards the future.

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Frailty needs to be a factor in drug development, proposed guidelines suggest

03/21/24 at 03:30 AM

Frailty needs to be a factor in drug development, proposed guidelines suggest McKnights Long-Term Care News, by Kristen Fischer; 3/20/24A new report on strategies for geriatric drug development and assessment determined that drugs need to consider age as well as other factors that older adults face such as cognitive impairment, frailty and polypharmacy. This is according to the International Union of Basic and Clinical Pharmacology (IUPHAR) Geriatric Committee, which published the report. The strategies specifically focused on integrating frailty as a factor in drug development. The report, published in the Journal of the American Geriatrics Society earlier this month, includes 12 principles pertaining to frailty in reference to drug development. The recommendations include measuring frailty at the start of when a person goes on a drug they’ll likely take regularly.

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Health care utilization and opioid use in patients receiving an integrated palliative care intervention for treatment of head and neck cancer compared to a historical control

03/20/24 at 03:00 AM

Health care utilization and opioid use in patients receiving an integrated palliative care intervention for treatment of head and neck cancer compared to a historical control Elsevier, International Journal of Radiation; by F. Rizwan. C. D'Avella, M. Albert, T. King, B. Egleston, T.J. Galloway, M. Chwistek, C. Fang, A. El-jawahri, J.R. Bauman; online access for 4/1/24 release Patients receiving chemoradiation therapy (CRT) for head and neck cancer (HNC) can develop significant symptomology (odynophagia, malnutrition) resulting in frequent hospitalizations and decreased quality of life (QOL) and continue to have chronic symptoms such as dysphagia and/or pain. The integration of a palliative care (PC) team during CRT has the potential to address the high symptom burden and improve QOL.

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Improvements in interdisciplinary communication following the implementation of a standardized Handoff Curriculum: SAFETIPS

03/20/24 at 02:30 AM

Improvements in Interdisciplinary Communication Following the implementation of a standardized Handoff Curriculum: SAFETIPS (Statistics, Assessment, Focused Plan, Pertinent Exam findings, to Dos, If/Thens, Pointers/Pitfalls, and Severity of Illness) Cureus, by Shaefali Shandilya and Justen M. Aprile; 3/18/24 Handoffs between medical providers serve a crucial patient safety function. While most published literature on the topic studies the handover process among physicians, robust literature is available on interdisciplinary medical communication. Little is known about the downstream effects of effective physician handover on subsequent physician and nursing interactions. ...Results: Statistical analysis revealed significant post-intervention mean score increases of one full point in four categories, namely organization and efficiency, communication, content, and clinical judgment.

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Preventing adverse drug events in hospice care

03/18/24 at 03:00 AM

Preventing adverse drug events in hospice care Hospice News, by Holly Vossel; 3/15/24 Documentation errors and a fragmented health system pose the greatest risks for adverse drug events among hospices. ... Evaluating these risks involves having solid medication reconciliation processes in place — both at the time of a patient’s admission and throughout their end-of life care experience, according to Mary Lynn McPherson, professor and executive program director of advanced post-graduate education in palliative care at the University of Maryland’s School of Pharmacy. McPherson also serves on the board of the American Academy of Hospice and Palliative Medicine (AAHPM).

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Antidepressant prescribing practices of pediatric palliative care providers

03/14/24 at 03:00 AM

Antidepressant prescribing practices of pediatric palliative care providers Journal of Palliative Medicine, by Teresa Venta; 3/12/24 Objective: This study seeks to describe the antidepressant prescribing practices of PPC providers and describe their level of training and comfort in assessing for anxiety and depression and prescribing psychotropic medications. Conclusions: Limited training in assessing mental health concerns, prescribing, and managing psychopharmacology suggests an opportunity for more targeted education for pediatric PC providers regarding antidepressant prescribing practices.

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ACC updates HFrEF Decision Pathway, reinforcing the Four Pillars of Therapy

03/13/24 at 03:00 AM

ACC updates HFrEF Decision Pathway, reinforcing the Four Pillars of Therapy

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Description and outcomes of a palliative care pharmacist-led Transitions of Care program

03/11/24 at 02:00 AM

Description and outcomes of a palliative care pharmacist-led Transitions of Care program J Palliat Med, by Connor McCormick, Mamta Bhatnagar, Robert M Arnold, Maria Felton Lowry; 3/6/24Background: Patients with palliative care needs are at high risk of medication errors during transitions of care (TOC). Palliative Care Pharmacist Interventions surrounding Medication Prescribing Across Care Transitions (IMPACT) program was developed to improve the TOC process from hospital to community setting for cancer patients followed by palliative care. Conclusion: Our pilot study demonstrates that integrating a pharmacist in TOC for seriously ill patients is feasible and valuable.

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Pharmacy associations join forces to advocate for pharmacists during change healthcare outage

03/05/24 at 03:00 AM

Pharmacy associations join forces to advocate for pharmacists during change healthcare outageNewswire Press Release; 3/3/24 Association executives from the American Pharmacists Association (APhA), the National Community Pharmacists Association (NCPA), the National Alliance of State Pharmacy Associations (NASPA), and the American Society of Consultant Pharmacists (ASCP) released an open letter to pharmacy benefit manager (PBM) executives and other insurance payers whose systems may have been impacted by the Change Healthcare outage. Pharmacists and pharmacies are asking for assurances that claims fulfilled during this outage will be paid, and paid in a timely manner, considering the challenges faced by pharmacies and pharmacists with predicting co-payments and determining eligibility and coverage. 

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Subcutaneous patient-controlled analgesia in home-based palliative care: "It's as straightforward as pushing a button, right at my fingertips"

02/28/24 at 03:00 AM

Subcutaneous patient-controlled analgesia in home-based palliative care: "It's as straightforward as pushing a button, right at my fingertips" J Pain Palliat Care Pharmacother, by Miguel Julião, Patrícia Calaveiras, Eduardo Bruera, Paulo Faria de Sousa; 2/26/24Subcutaneous patient-controlled analgesia (SCPCA) in home-based palliative care is a potentially valuable option for providing effective pain relief to some patients, particularly when conventional analgesic approaches prove ineffective or are refused.

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Reimagining end-of-life care: Balancing polypharmacy, treatment modification, and quality of life in advanced cancer patients

02/19/24 at 03:00 AM

Reimagining end-of-life care: Balancing polypharmacy, treatment modification, and quality of life in advanced cancer patientsBNN, by Mahnoor Jehangir; 2/15/24In a recent groundbreaking study, researchers have illuminated the complexities surrounding polypharmacy and the prescription of potentially inappropriate medications (PIMs) to patients at the end of their lives, particularly those battling advanced cancer. This investigation, involving a cohort of 265 older adults, sheds light on the nuanced challenges and critical decisions faced by healthcare providers in managing the delicate balance between treatment efficacy and quality of life for terminally ill patients. 

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CMS issues additional guidance on program to allow people with Medicare to pay out-of-pocket prescription drug costs in monthly payments

02/19/24 at 02:30 AM

CMS issues additional guidance on program to allow people with Medicare to pay out-of-pocket prescription drug costs in monthly paymentsCMS.gov; 2/15/24The Inflation Reduction Act’s Medicare Prescription Payment Plan will allow people to pay Medicare Part D out-of-pocket costs over the course of the year starting in 2025. [On February 15th,] the Centers for Medicare & Medicaid Services (CMS) released the second part of draft guidance for the Medicare Prescription Payment Plan that outlines requirements for Medicare Part D plan sponsors, including outreach and education requirements, pharmacy processes, and operational considerations, for the program’s first year, 2025. 

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Palliative care’s psychedelic future

02/16/24 at 03:00 AM

Palliative care’s psychedelic futuretruthdig, by Jane C. Hu; 2/14/24In Oregon, hospice doctors are expanding the menu of treatments for end-of-life anxiety and depression.

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Pharmacy in suit files for bankruptcy

02/15/24 at 03:00 AM

Pharmacy in suit files for bankruptcySan Antonio Express News, by Patrick Danner; 2/12/24County's litigation targets Trinity along with major retailers for the amount of opioids it dispensed. ... A lawyer for the county dubbed it a "pill mill." ... Trinity Pharmacies said in a court filing that 99% of prescriptions it fills are for patients in hospice care.

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How PBM legislation would transform the industry

02/08/24 at 03:00 AM

How PBM legislation would transform the industryModern Healthcare, by Lauren Berryman; 1/24/24The pharmacy benefit manager industry could look a lot different soon if Congress follows through with bipartisan efforts to pass bills governing the sector. PBMs such as CVS Caremark, Express Scripts and OptumRx would face new transparency requirements that would give health insurance companies, employers, customers and regulators new insights into how they negotiate prices for prescription medicines—and how much of the savings they generate find their way to patients and plan sponsors. Pending legislation also would prohibit lucrative practices such as spread pricing.

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Strategies for positive change in opioid prescribing

02/06/24 at 04:00 AM

Strategies for positive change in opioid prescribingPharmacy Times; 2/1/24This is a video synopsis/summary of a Practice Pearls featuring Ryan Haumschild, PharmD, MS, MBA, CPEL; Megan Mitchell, PharmD, MS; Stephanie Abel, PharmD, BCPS; and Jennifer Grate, CPhT. Haumschild discusses the importance of positive change in opioid stewardship. 

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A pathophysiological approach for selecting dedications to treat nociceptive and neuropathic pain in servicemembers

02/05/24 at 04:00 AM

A pathophysiological approach for selecting medications to treat nociceptive and neuropathic pain in servicemembersMil Med, by Khan Thi Nguyen, Daniel W Beauchamp, Reginald B O'Hara; 1/31/24The prevalence of chronic pain of service members (SMs) in the U.S. is estimated to be higher (roughly 31-44%) compared to that of civilian population (26%). This higher prevalence is likely due to the high physical demands related combat and training injuries that are not immediately resolved and worsen over time. Mental Health America reports that chronic pain can lead to other mental health conditions such as severe anxiety, depression, bipolar disorder, and post-traumatic stress disorder.

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Hospices struggle to balance costs, patient needs in medication deprescribing

02/02/24 at 04:00 AM

Hospices struggle to balance costs, patient needs in medication deprescribingHospice News, by Jim Parker; 1/30/24When deprescribing medications for hospice patients, providers have to navigate a complex web of factors. But according to some clinicians, the prospect of cost savings often takes precedence over clinical outcomes. Medication costs are among hospices’ biggest expenses, and deprescribing some medications deemed “curative” or “unrelated” to the patient’s terminal diagnosis is a standard practice. However, even in the context of providing comfort care at the end of life, many patients do not receive medications that could benefit them, including those for pain management.

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Breakthroughs in Alzheimer's research give cause for optimism

02/01/24 at 03:30 AM

Breakthroughs in Alzheimer's research give cause for optimismKiplinger, by Elaine Silvestrini; 1/29/24... Finding a cure or even an effective treatment has been difficult. Now, after billions of dollars in research and more than 100 drug failures, advocates are celebrating breakthroughs, including drugs that for the first time treat the underlying causes of the disease. Experts are optimistic that we may be on the precipice of significant changes in how the disease is treated and potentially even prevented. 

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New research challenges the commonly held view that opioids are the most powerful pain relievers

01/24/24 at 04:00 AM

New research challenges the commonly held view that opioids are the most powerful pain relieversSciTechDaily, by University of Sydney; 1/21/24A University of Sydney-led study challenges the prevailing view of opioids as the most effective pain relievers for cancer, revealing significant evidence gaps and suggesting NSAIDs as a potential alternative. This research advocates for more informed choices in cancer pain management, emphasizing patient empowerment and the consideration of non-opioid options.

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