Literature Review

All posts tagged with “Clinical News | Pharmacy & Medication News.”



Drug discount program is exploiting poor patients while corporate giants profit

04/30/24 at 03:00 AM

Drug discount program is exploiting poor patients while corporate giants profit Minnesota Reformer; by David Balto; 4/26/24 ... The federal 340B drug discount program was created three decades ago to help economically vulnerable Americans access affordable prescription medications and providers in underserved areas expand and improve services. Under the program, drug companies participating in Medicaid — known in Minnesota as Medical Assistance — provide sizeable discounts as high as 50% to these ‘safety net’ health care facilities. ... Unfortunately, over time, the tens of billions of dollars flowing through this program have proven irresistible to for-profit corporate entities, including giant health systems and big box chain pharmacies — and there is no guarantee those discounts are reaching patients. 

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The Dos and Don’ts of enhanced service contracts

04/29/24 at 02:00 AM

The Dos and Don’ts of enhanced service contractsSpecialty Pharmacy Continuum; by Marcus A. Banks; 4/25/24 ... Any pharmacy that interacts with patients—an independent pharmacy, an ambulatory infusion clinic, a health system or specialty pharmacy—can enter an enhanced service contract with a pharmaceutical company. All services offered under these contracts should be documented, auditable and offered at fair prices. Before approaching the company about partnering, Mr. Suchanek advised understanding the distinction between basic and enhanced services. ... “Pharmacy leaders need to demonstrate that they are credible partners,” [David] Suchanek said [Executive Vice President for  Biotech & Specialty Services at D2 Solutions].

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AI could play role in preventing prescribing of unnecessary drugs in older adults

04/26/24 at 03:00 AM

AI could play role in preventing prescribing of unnecessary drugs in older adults McKnights Senior Living, by Kristen Fischer; 4/22/24 A new study finds that artificial intelligence could encourage doctors to stop prescribing drugs that aren’t necessary — especially in older adults, who tend to be on multiple medications. The report was published 4/18 in the Journal of Medical Systems. More than 40% of older adults are taking five or more prescription medications, a rate that raises their risk for potentially harmful drug interactions. ... AI isn’t a perfect tool compared with having an actual doctor. For instance, it tended not to pay much attention to a person’s pain level, suggesting that the patient stop taking pain medications but not others for clinical ailments such as high cholesterol or high blood pressure, the authors reported.

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Cardinal Health, OptumRx break up

04/26/24 at 03:00 AM

Cardinal Health, OptumRx break up Becker's Hospital Review, by Paige Twenter; 4/22/24Cardinal Health's pharmaceutical distribution contracts with OptumRx, a subsidiary of UnitedHealth Group, will not be renewed, the medical distributor said April 22.  The contracts, which mainly included non-specialty bulk shipments to Optum's mail dispensing sites, will expire in late June. In 2023, sales to OptumRx generated 16% of Cardinal Health's consolidated revenue. "Total sales to OptumRx generate a meaningfully lower operating margin than the overall pharmaceutical and specialty solutions segment," Cardinal said. McKesson Corp. won the contract, according to Bloomberg, which cited Evercore ISI. 

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Comparative effectiveness of acupuncture vs massage for relieving pain in patients with advanced cancer

04/19/24 at 03:00 AM

Comparative effectiveness of acupuncture vs massage for relieving pain in patients with advanced cancer The ASCO Post; by Jun J. Mao, MD, MSCE and Andrew S. Epstein, MD; 4/17/24... The IMPACT study was conducted at Memorial Sloan Kettering Cancer Center and regional sites in New York, New Jersey, and Florida to evaluate the long-term comparative effectiveness of acupuncture vs massage for pain in patients with advanced cancer. ... The primary outcome—change in worst pain intensity score from baseline to 26 weeks—was measured using the Brief Pain Inventory (BPI ranging from 0–10; higher numbers indicate worse pain intensity or interference). The secondary outcomes included fatigue, insomnia, and quality of life. ... To use these therapies, it is important to seek credentialed practitioners who have training or experience in working with patients who have cancer. 

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Governor Lamont annnounces $35.5 million in state grants to support nonprofit providers with capital improvement projects [$775 thousand to Connecticut Hospice]

04/12/24 at 03:00 AM

Governor Lamont announces $35.5 million in state grants to support nonprofit providers with capital improvement projects [$775 thousand to Connecticut Hospice]  State of Connecticut, Office of the Governor; 4/10/24 Governor Ned Lamont today announced that his administration is awarding approximately $35.5 million in state funding to nonprofit providers across Connecticut for capital improvement projects that support each respective organization in their mission of delivering services to some of the state’s most vulnerable residents. The grants are being released through the state’s Nonprofit Grant Program, which is administered by the Connecticut Office of Policy and Management. [The list includes:] ... "Branford – Connecticut Hospice: $775,000 (Pharmacy Improvements)"

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‘We’re the telescope looking forward’: Medical ethicists ask tough questions as part of $66 million research project

04/09/24 at 03:00 AM

‘We’re the telescope looking forward’: Medical ethicists ask tough questions as part of $66 million research project CU Department of Medicine, by Mark Harden; 4/5/24 In the original “Jurassic Park” movie, after the process of bringing dinosaurs back to life is explained to a team of consultants, one of them voices a warning: “Your scientists were so preoccupied with whether or not they could, they didn’t stop to think if they should.” University of Colorado Department of Medicine faculty members will be asking the “should” question years before there’s an answer to “could.” They’ve joined in a nationwide study of whether tiny, battery-powered electric devices and genetic material, swallowed in capsule form, could one day replace surgery or injections as treatments for metabolic diseases such as diabetes and obesity.

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Chicago area nurse gets 2 years in prison for stealing morphine from sick patients

04/08/24 at 03:00 AM

Chicago area nurse gets 2 years in prison for stealing morphine from sick patientsCBS News TV 2, Chicago; by Acacia Hernandez; 4/4/24A northwest suburban nurse was sentenced in court on Thursday to two years in federal prison for stealing morphine from her patients, some of whom were terminally ill. Sarah Diamond, 31, of Woodstock, was accused of targeting the most vulnerable, including hospice patients living out their final days. In 2021, she removed liquid morphine from bottles that had been prescribed to at least five hospice patients and replaced it with saline. Prosecutors said she took the medication for her own personal use.

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Cancer patients often want ‘one more round.’ Should doctors say no?

04/02/24 at 03:00 AM

Cancer patients often want ‘one more round.’ Should doctors say no? The Washington Post, by Mikkael A. Sekeres, MD; 3/31/24 My patient was in his early 30s and his leukemia had returned again following yet another round of treatment. He was a poster child for the recently reported rise in cancer rates in the young, and had just asked me what chemotherapy cocktail I could devise for him next, to try to rid him of his cancer. I hesitated before answering. Oncologists are notorious for always being willing to recommend to our patients one more course of treatment, even when the chances of success are negligible.  

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Antibiotics in end-of-life care

03/29/24 at 03:00 AM

Antibiotics in end-of-life care NEJM Journal Watch, by Abigail Zuger, MD; 3/27/24Antibiotics often are considered to be among the gentler and more comfort-oriented interventions in end-of-life care, certainly far less aggressive than intubation or last-ditch surgery. ... Still, antibiotics do entail their own costs in the form of toxicities and need for intravenous access, and liberal antibiotic use reliably worsens institutional and community drug-resistance profiles. ... A new review was written for infectious disease consultants but contains specific suggestions that should interest both generalists and other subspecialists caring for dying patients. 

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Expanding the use of continuous sedation until death and physician-assisted suicide

03/29/24 at 03:00 AM

Expanding the use of continuous sedation until death and physician-assisted suicide  The Journal of Medicine & Philosophy: A Forum for Bioethics and Philosophy of Medicine; by Samuel H Lipuma and Joesph P Demarco; 3/27/24 The controversy over the equivalence of continuous sedation until death (CSD) and physician-assisted suicide/euthanasia (PAS/E) provides an opportunity to focus on a significant extended use of CSD. 

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Nurse arrested after morphine, other stolen medical drugs seized in Owensboro

03/28/24 at 03:00 AM

Nurse arrested after morphine, other stolen medical drugs seized in Owensboro14 News WFIE, by Aaron Chatman; 3/26/24 Eight suspects were arrested and facing numerous charges after a massive drug bust in Owensboro. That’s according to the Daviess County Sheriff’s Office, who says they opened an investigation after receiving dozens of tips about a drug trafficking operation at the home of Pamela Bartimus. Deputies say Bartimus was an employee of Hospice & Palliative Care of Western Kentucky and had been stealing medication at her job.

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Partners In Care sets sights on service diversification, hospice-pharmacy partnership

03/26/24 at 03:00 AM

Partners In Care sets sights on service diversification, hospice-pharmacy partnership Hospice News, by Jim Parker; 3/22/24 Hospice providers need to evolve with their changing patient populations and the larger health care system, according to Greg Hagfors, CEO of Partners In Care. The Oregon-based hospice, palliative care and home health provider recently celebrated the 45th anniversary of its founding, which preceded the establishment of the Medicare Hospice Benefit. ... Hospice News recently spoke with Hagfors about the ways the industry has changed since Partners In Care came on the scene — and how it is moving towards the future.

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Frailty needs to be a factor in drug development, proposed guidelines suggest

03/21/24 at 03:30 AM

Frailty needs to be a factor in drug development, proposed guidelines suggest McKnights Long-Term Care News, by Kristen Fischer; 3/20/24A new report on strategies for geriatric drug development and assessment determined that drugs need to consider age as well as other factors that older adults face such as cognitive impairment, frailty and polypharmacy. This is according to the International Union of Basic and Clinical Pharmacology (IUPHAR) Geriatric Committee, which published the report. The strategies specifically focused on integrating frailty as a factor in drug development. The report, published in the Journal of the American Geriatrics Society earlier this month, includes 12 principles pertaining to frailty in reference to drug development. The recommendations include measuring frailty at the start of when a person goes on a drug they’ll likely take regularly.

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Health care utilization and opioid use in patients receiving an integrated palliative care intervention for treatment of head and neck cancer compared to a historical control

03/20/24 at 03:00 AM

Health care utilization and opioid use in patients receiving an integrated palliative care intervention for treatment of head and neck cancer compared to a historical control Elsevier, International Journal of Radiation; by F. Rizwan. C. D'Avella, M. Albert, T. King, B. Egleston, T.J. Galloway, M. Chwistek, C. Fang, A. El-jawahri, J.R. Bauman; online access for 4/1/24 release Patients receiving chemoradiation therapy (CRT) for head and neck cancer (HNC) can develop significant symptomology (odynophagia, malnutrition) resulting in frequent hospitalizations and decreased quality of life (QOL) and continue to have chronic symptoms such as dysphagia and/or pain. The integration of a palliative care (PC) team during CRT has the potential to address the high symptom burden and improve QOL.

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Improvements in interdisciplinary communication following the implementation of a standardized Handoff Curriculum: SAFETIPS

03/20/24 at 02:30 AM

Improvements in Interdisciplinary Communication Following the implementation of a standardized Handoff Curriculum: SAFETIPS (Statistics, Assessment, Focused Plan, Pertinent Exam findings, to Dos, If/Thens, Pointers/Pitfalls, and Severity of Illness) Cureus, by Shaefali Shandilya and Justen M. Aprile; 3/18/24 Handoffs between medical providers serve a crucial patient safety function. While most published literature on the topic studies the handover process among physicians, robust literature is available on interdisciplinary medical communication. Little is known about the downstream effects of effective physician handover on subsequent physician and nursing interactions. ...Results: Statistical analysis revealed significant post-intervention mean score increases of one full point in four categories, namely organization and efficiency, communication, content, and clinical judgment.

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Preventing adverse drug events in hospice care

03/18/24 at 03:00 AM

Preventing adverse drug events in hospice care Hospice News, by Holly Vossel; 3/15/24 Documentation errors and a fragmented health system pose the greatest risks for adverse drug events among hospices. ... Evaluating these risks involves having solid medication reconciliation processes in place — both at the time of a patient’s admission and throughout their end-of life care experience, according to Mary Lynn McPherson, professor and executive program director of advanced post-graduate education in palliative care at the University of Maryland’s School of Pharmacy. McPherson also serves on the board of the American Academy of Hospice and Palliative Medicine (AAHPM).

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Antidepressant prescribing practices of pediatric palliative care providers

03/14/24 at 03:00 AM

Antidepressant prescribing practices of pediatric palliative care providers Journal of Palliative Medicine, by Teresa Venta; 3/12/24 Objective: This study seeks to describe the antidepressant prescribing practices of PPC providers and describe their level of training and comfort in assessing for anxiety and depression and prescribing psychotropic medications. Conclusions: Limited training in assessing mental health concerns, prescribing, and managing psychopharmacology suggests an opportunity for more targeted education for pediatric PC providers regarding antidepressant prescribing practices.

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ACC updates HFrEF Decision Pathway, reinforcing the Four Pillars of Therapy

03/13/24 at 03:00 AM

ACC updates HFrEF Decision Pathway, reinforcing the Four Pillars of Therapy

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Description and outcomes of a palliative care pharmacist-led Transitions of Care program

03/11/24 at 02:00 AM

Description and outcomes of a palliative care pharmacist-led Transitions of Care program J Palliat Med, by Connor McCormick, Mamta Bhatnagar, Robert M Arnold, Maria Felton Lowry; 3/6/24Background: Patients with palliative care needs are at high risk of medication errors during transitions of care (TOC). Palliative Care Pharmacist Interventions surrounding Medication Prescribing Across Care Transitions (IMPACT) program was developed to improve the TOC process from hospital to community setting for cancer patients followed by palliative care. Conclusion: Our pilot study demonstrates that integrating a pharmacist in TOC for seriously ill patients is feasible and valuable.

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Pharmacy associations join forces to advocate for pharmacists during change healthcare outage

03/05/24 at 03:00 AM

Pharmacy associations join forces to advocate for pharmacists during change healthcare outageNewswire Press Release; 3/3/24 Association executives from the American Pharmacists Association (APhA), the National Community Pharmacists Association (NCPA), the National Alliance of State Pharmacy Associations (NASPA), and the American Society of Consultant Pharmacists (ASCP) released an open letter to pharmacy benefit manager (PBM) executives and other insurance payers whose systems may have been impacted by the Change Healthcare outage. Pharmacists and pharmacies are asking for assurances that claims fulfilled during this outage will be paid, and paid in a timely manner, considering the challenges faced by pharmacies and pharmacists with predicting co-payments and determining eligibility and coverage. 

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Subcutaneous patient-controlled analgesia in home-based palliative care: "It's as straightforward as pushing a button, right at my fingertips"

02/28/24 at 03:00 AM

Subcutaneous patient-controlled analgesia in home-based palliative care: "It's as straightforward as pushing a button, right at my fingertips" J Pain Palliat Care Pharmacother, by Miguel Julião, Patrícia Calaveiras, Eduardo Bruera, Paulo Faria de Sousa; 2/26/24Subcutaneous patient-controlled analgesia (SCPCA) in home-based palliative care is a potentially valuable option for providing effective pain relief to some patients, particularly when conventional analgesic approaches prove ineffective or are refused.

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Reimagining end-of-life care: Balancing polypharmacy, treatment modification, and quality of life in advanced cancer patients

02/19/24 at 03:00 AM

Reimagining end-of-life care: Balancing polypharmacy, treatment modification, and quality of life in advanced cancer patientsBNN, by Mahnoor Jehangir; 2/15/24In a recent groundbreaking study, researchers have illuminated the complexities surrounding polypharmacy and the prescription of potentially inappropriate medications (PIMs) to patients at the end of their lives, particularly those battling advanced cancer. This investigation, involving a cohort of 265 older adults, sheds light on the nuanced challenges and critical decisions faced by healthcare providers in managing the delicate balance between treatment efficacy and quality of life for terminally ill patients. 

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CMS issues additional guidance on program to allow people with Medicare to pay out-of-pocket prescription drug costs in monthly payments

02/19/24 at 02:30 AM

CMS issues additional guidance on program to allow people with Medicare to pay out-of-pocket prescription drug costs in monthly paymentsCMS.gov; 2/15/24The Inflation Reduction Act’s Medicare Prescription Payment Plan will allow people to pay Medicare Part D out-of-pocket costs over the course of the year starting in 2025. [On February 15th,] the Centers for Medicare & Medicaid Services (CMS) released the second part of draft guidance for the Medicare Prescription Payment Plan that outlines requirements for Medicare Part D plan sponsors, including outreach and education requirements, pharmacy processes, and operational considerations, for the program’s first year, 2025. 

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Palliative care’s psychedelic future

02/16/24 at 03:00 AM

Palliative care’s psychedelic futuretruthdig, by Jane C. Hu; 2/14/24In Oregon, hospice doctors are expanding the menu of treatments for end-of-life anxiety and depression.

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