Literature Review

All posts tagged with “Clinical News | Pharmacy & Medication News.”



Revamped tool can reliably assess pain symptoms in dementia patients: researchers

03/19/25 at 02:00 AM

Revamped tool can reliably assess pain symptoms in dementia patients: researchers McKnights Long-Term Care News; by Zee Johnson; 3/17/25 ... A team of researchers reconstructed the End-of-Life Dementia-Comfort Assessment in Dying, or EOLD-CAD, after a multifacility study showed that caregivers could adequately and reliably address a host of pain symptoms seen in end-of-life dementia patients. ... When clinicians working in the SNFs that were part of the trials used the EOLD-CAD, they were able to detect patterns in more than 600 residents that fell into four categories: physical distress, symptoms of dying, emotional distress, and well-being. Common symptoms observed across these categories were restlessness, shortness of breath, choking, gurgling, difficulty in swallowing, fear and anxiety. ...

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Pharmacies of the future: 4 keys to reinvention

03/18/25 at 03:00 AM

Pharmacies of the future: 4 keys to reinventionForbes; by Jenn Vande Zande; 3/11/25... “To continue to meet growing patient needs, we must evolve how community pharmacy works and, most importantly, how we support our pharmacy teams to create a sustainable future for community pharmacy,” Prem Shah, president of pharmacy and consumer wellness at CVS Health, said, referring to findings from the company’s Rx Report from January 2024. Based on those findings, CVS says there’s a “critical need for sustainable and scalable industry-wide change, such as operational improvements and digital innovations to better support pharmacy teams behind the counter.” Here are four focus areas for pharmacies to bring about that change:

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Hospice Insights Podcast - Psychedelics and end of life care: Understanding the legal landscape

03/17/25 at 03:00 AM

Hospice Insights Podcast - Psychedelics and end of life care: Understanding the legal landscape Hospice Insight - The Law and Beyond; by Husch Blackwell LLP; 3/12/25 There has been a lot of buzz around psychedelics, and particularly their potential usefulness in treating existential suffering at the end of life. Husch Blackwell was the first law firm in the country to establish a Psychedelics & Emerging Therapies practice group devoted to helping clinicians, researchers, and investors navigate the complex and difficult legal and regulatory issues involved in developing new therapies in this space. In this episode, host Meg Pekarske is joined by the leaders of Husch Blackwell’s Psychedelics & Emerging Therapies practice group, Kimberly Chew, Karen Luong, and Natasha Sumner, who provide an overview of what psychedelics are, their legal status under federal and state laws, and liability considerations for clinicians.

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CMS pulls plug on projects aimed at improving care, saving on costs

03/14/25 at 03:00 AM

CMS pulls plug on projects aimed at improving care, saving on costs KFF Health News - Morning Briefing; 3/13/25 One initiative that has been scrapped would have offered some generic drugs to Medicare enrollees for $2. Meanwhile, the Trump administration has backed off hospice oversight.

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Walgreens sells to private equity firm Sycamore Partners

03/13/25 at 03:10 AM

Walgreens sells to private equity firm Sycamore Partners Healthcare Brew - Pharma; by Nicole Ortiz; 3/11/25 Since December, rumors have floated around that Walgreens was going to be acquired by private equity (PE) firm Sycamore Partners. And while analysts told Healthcare Brew at the time that it was unlikely to happen, the tides appear to have turned in the PE company’s favor. On March 6, Walgreens Boots Alliance announced in a press release that it had signed a definitive purchase agreement with Sycamore for up to $23.7 billion. However, when Walgreens’s debts and assets to be potentially divested are taken out, the total sale price is actually closer to around $10 billion, per the ll Street Journal, turning the retailer into a private entity after nearly a century as a public company.

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Assessing pain, anxiety and other symptoms of nursing home residents unable to speak for themselves

03/11/25 at 03:00 AM

Assessing pain, anxiety and other symptoms of nursing home residents unable to speak for themselves Regenstrief Institute, Indianapolis, IN; by Kathleen T. Unroe, MD, MHA; 3/10/25 Revamped tool reliably addresses physical and emotional distress, well-being and end-of-life symptoms. As many as half of nursing home residents are cognitively impaired and may be unable to communicate symptoms such as pain or anxiety to the staff and clinicians caring for them. Therefore, information needed for the evaluation of symptoms and subsequent treatment decisions typically does not reliably exist in nursing home electronic health records (EHRs). A new paper reports on the novel adaptation of a commonly used symptom assessment instrument to more comprehensively acquire this difficult-to-obtain data with the ultimate goal of enabling knowledge-based expansion of palliative care services in nursing homes to address residents’ symptoms. 

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Hallucinogens may elevate death risk by more than twofold

03/11/25 at 03:00 AM

Hallucinogens may elevate death risk by more than twofold Medscape; by Liz Scherer; 3/5/25 Hallucinogens are associated with a 2.6-fold increased risk for premature death in some individuals seeking emergency care, according to a recent study. The risks are especially substantial in vulnerable patients who are suicidal, who are susceptible to severe mental illness, or have comorbid conditions such as respiratory disease or cancer. The findings come at a time of renewed interest in the therapeutic potential of substances like psilocybin, lysergic acid diethylamide, methylenedioxymethamphetamine (MDMA), and ketamine for mood and substance use disorders. In 2023, the Canadian Institutes of Health Research allocated roughly $3 million to three clinical trials examining psilocybin-assisted psychotherapy in the treatment of alcohol use disorder, treatment-resistant depression, and end-of-life psychological distress in patients with advanced cancer.

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Local pharmacist advising Ohio health director on palliative care

03/11/25 at 03:00 AM

Local pharmacist advising Ohio health director on palliative care Herald-Star, Steubenville, OH; by Christopher Dacanay; 3/10/25 A local pharmacist hopes to “expand utilization” of palliative care in Jefferson County and increase patients’ quality of life from her new position as an adviser to the Ohio Department of Health director. Steubenville resident Mary Mihalyo, doctor of pharmacy, was appointed Dec. 10 to the Palliative Care and Quality of Life Interdisciplinary Council. Bringing her own expertise, Mihalyo joins a diverse, 20-person group of professionals with experience in the provision of palliative care. ... Mihalyo, who founded Steubenville’s A&B Pharmacy with her husband, is the former CEO of Delta Care Rx LLC. She now serves as chief clinical officer for the company, which has been rebranded as Dragonfly Health. ... Her professional work, since [1999], has focused on serving hospice and palliative care patients locally and nationally as part of interdisciplinary teams. ... [Council members] ... actively consult with and advise the director on palliative care initiatives in the state, identify standards of practice, pinpoint initiatives at the state or national level integrating palliative care into the healthcare system and developing its practice and lay out patient identification guidelines for health care providers.

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Charges dismissed against chef accused of trying to kill his Monterey county mother

03/04/25 at 03:00 AM

Charges dismissed against chef accused of trying to kill his Monterey county mother KSBW Action News-8, Monterey, CA; by Felix Cortez; 2/28/25 A popular San Francisco area chef who was arrested along with his sister and charged with trying to kill their mother more than two years ago has had attempted murder charges dismissed against him. “In over 30 years of practice, this was one of the saddest cases I have ever seen and one of the most incompetent investigations by the Monterey County Sheriff’s Department that I have ever seen,” said Juliet Peck, the attorney for James Stolich. ... The mother was terminally ill and lived on a ranch off Highway 68 outside Salinas. “James’ mother’s only wish was to die at home without pain, surrounded by her daughter, son, and pets,” Peck said. But that never happened; Tinker died about a week later in a hospice facility, never to see her children again, because an emergency protective order obtained by the sheriff’s office prevented the children from visiting their dying mother. ... According to court documents, the daughter, Whitney, was the “agent designated to make all health care decisions for her mother,” which included administering medication to help alleviate her mother’s pain. ...The original criminal complaint alleging attempted murder charges said Whitney or a co-conspirator “crushed up pills with a mallet.” A close friend of Tinker was willing to testify that Whitney had no intent to kill her mother but was simply following her mother’s “directive to provide effective and sufficient palliative care even if it hastened her death.”Editor's note: This case raises numerous issues, including but not limited to community education (including law enforcement), Advance Directives, patient and caregiver education and support, MAiD (Medical Aid in Dying) or the End Of Life Option Act (EOLOA) in California, ethics, and the dying process (note that "the mother died about a week later in a hospice facility). 

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Daughter indicted for killing mother with morphine in Evans

02/26/25 at 03:00 AM

Daughter indicted for killing mother with morphine in Evans The Augusta Press, Augusta, GA; by Greg Rickabaugh; 2/25/25The daughter of a woman who died in an Evans assisted living home from a fatal dose of morphine has been indicted for malice murder. Rachel Elaine Waters, 41, is expected to surrender this week on murder charges in the death of 74-year-old Marsha Sprayberry Foster, according to Columbia County authorities.An indictment says that Waters administered a lethal dose of morphine on July 12, 2023, while her mother was at the Marshall Pines assisted living on North Belair Road. The cause of death was determined in an autopsy, showing that excessive use of the unprescribed morphine was the reason for her death. Foster had Alzheimer’s disease, and the morphine was reportedly left behind by hospice workers and used by the daughter without authorization.

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Center for Hospice Care's BreatheEazy Program supports patients with respiratory issues

02/18/25 at 03:00 AM

Center for Hospice Care's BreatheEazy Program supports patients with respiratory issues LaporteCounty.Life; by Garrett Spoor; 2/13/25 One of the toughest health challenges a person can face is the trouble of breathing. Center for Hospice Care comes across a lot of patients who experience this issue and encourages many of them to become a part of their BreatheEazy program. Dr. Karissa Misner, medical director at Center for Hospice Care, considers the BreatheEazy program to be a monumental boost for patients who might have respiratory issues. “This is a specialized pulmonary program for our patients with chronic obstructive pulmonary disease,” Misner said. “It can also be used for many other terminal diagnoses that affect the lungs. Whenever there is any type of illness that causes difficulty in breathing, we can utilize this program.”

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People with depression develop long-term health conditions quicker than those without, study finds

02/17/25 at 03:00 AM

People with depression develop long-term health conditions quicker than those without, study finds McKnights Home Care; by Kristen Fischer; 2/13/25 Adults who have experienced depression develop long-term physical conditions about 30% faster than those without depression, a new study finds. Authors of the report said depression needs to be viewed as a “whole body” condition, with treatment approaches that address mental and physical health. The report was published Thursday [2/13/25] in PLOS Medicine. Investigators evaluated the association between depression and the rate at which conditions accrued in midlife and older age.

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Kroger partners with Express Scripts to expand pharmacy services

02/10/25 at 03:00 AM

Kroger partners with Express Scripts to expand pharmacy services Becker's Hospital Review; by Alexandra Murphy; 2/6/25 Cincinnati-based Kroger Health has reached a new agreement with Express Scripts, the pharmacy benefit services arm of Evernorth, to provide access to prescription medications and health services at the Kroger Family of Pharmacies for Express Scripts Customers. Under the new agreement, the Kroger Family of Pharmacies will resume serving customers in Express Scripts' Medicare Part D and Tricare/Department of Defense plans, according to a Feb. 5 Kroger news release. This comes after Kroger ended its contract with Express Scripts in September of 2022, after months of unsuccessful negotiations over a new agreement. 

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Suzetrigine: First-in-class nonopioid pain therapy is approved by FDA

02/08/25 at 03:15 AM

Suzetrigine: First-in-class nonopioid pain therapy is approved by FDAAmerican Journal of Managed Care; Giuliana Grossi; 1/25Suzetrigine (Journavx; Vertex Pharmaceuticals) received approval from the FDA for the treatment of adults with moderate-to-severe acute pain, according to an announcement from Vertex. The therapy is a novel oral, non-opioid, highly selective NaV1.8 pain signal inhibitor ... offering a non-opioid alternative amid the opioid crisis. Clinical trials demonstrated significant efficacy in postsurgical pain relief, though results varied across different conditions. Despite this, suzetrigine offers the potential to energize the nonopioid pain market, which includes other companies like Tris Pharma, Latigo Biotherapeutics, and SiteOne Therapeutics—all actively developing alternatives to opioids. Key findings from the Institute for Clinical and Economic Review analysis of the phase 3 trials include potential lifetime cost savings of $200 per patient when comparing suzetrigine with opioids, assuming a 1-week course priced at $420.

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Opioid painkillers less available to people of color

01/31/25 at 03:00 AM

Opioid painkillers less available to people of color HealthDay News / Coastal Breeze News, Marco Island, FL; 1/30/25 People of color now have less access to prescription opioid painkillers than white patients, an unintended consequence of efforts to stem America’s opioid epidemic. Communities of color have a 40% to 45% lower distribution of commonly prescribed opioids, compared to majority white communities, researchers reported in a study published Jan. 23 in the journal Pain. This could prevent opioid painkillers from reaching those in true need of them, like cancer patients, researchers said. 

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Grant renews funding for pain and aging center

01/31/25 at 03:00 AM

Grant renews funding for pain and aging center Cornell Chronicle; by Weill Cornell Medicine; 1/30/25 The Translational Research Institute for Pain in Later Life (TRIPLL), a New York City-based center to help older adults prevent and manage pain, has been awarded a five-year, $5 million renewal grant from the National Institute on Aging (NIA). ... The institute seeks to apply insights from psychology, sociology, economics and communications to develop and implement effective pain management techniques that are acceptable to and practical for older adults.

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DEA proposed telemedicine prescribing rule could burden hospice physicians and hospice operations

01/29/25 at 03:00 AM

DEA proposed telemedicine prescribing rule could burden hospice physicians and hospice operations Morgan Lewis, Washington, DC; by Howard J. Young, Jacob J. Harper, and Roshni Edalur; 1/27/25 Signaling a possible future approach to regulating Schedule II-V prescribing via telemedicine in lieu of in-person examinations, on January 17 the DEA issued a notice of proposed rulemaking regarding its next iteration of controlled substance prescribing controls. With comments due March 18, 2025, the Proposed Rule is not subject to the Trump administration’s executive order freeze on new proposed regulations. [Click on the title's link to continue reading.]

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Why drug prices & modern tech matter in hospice care, too, with Nick Opalich

01/28/25 at 03:00 AM

Why drug prices & modern tech matter in hospice care, too, with Nick Opalich Capital Rx; podcast with Nick Opalich; 1/24/25 For Episode 51 of the Astonishing Healthcare podcast, we spoke with Nick Opalich, CEO of HospiceChoice Rx. We learned about how end-of-life care is evolving in the U.S., including the roles pharmacy and technology play in the hospice industry. Nick discusses some similarities between the hospice pharmacy benefit management (PBM) and commercial PBM spaces, such as the importance of a great pharmacy network and independent pharmacies, why the drug price index matters (NADAC vs. AWP), medication access, and disconnected systems. A former pharmacy owner himself, Nick explains the importance of helping hospice providers control drug spend, which is usually the second highest cost behind labor, and reimbursement trends/pressure. 

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Disproportionate use of aid in dying among people with ALS: Why ALS aid-in-dying requests are common while ALS is rare

01/25/25 at 03:10 AM

Disproportionate use of aid in dying among people with ALS: Why ALS aid-in-dying requests are common while ALS is rareJournal of Aid-in-Dying Medicine; Carolyn Rennels, MD; Steven Z. Pantilat, MD FAAHPM, MHM; Ambereen K. Mehta, MD, MPH, FAAHPM; Allison Kestenbaum, MA, MPA, BCC-PCHAC, ACPE; Kelsey Noble, DO; Jessica Besbris, MD; Ali Mendelson, MD; Kara Bischoff, MD; 12/24People with amyotrophic lateral sclerosis (ALS) disproportionately use aid in dying. We explore aspects of the ALS experience that may help explain the higher rates of aid-in-dying requests in this disease relative to others. In particular, the desire to maintain control is prominent in the face of a relentlessly progressive disease that results in substantial disability. We also describe how the requirement for self-administration of aid-in-dying medications impacts people with ALS.

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FTC releases second interim staff report on prescription drug middlemen: Report finds PBMs charge significant markups for cancer, HIV, and other critical specialty generic drugs

01/25/25 at 03:00 AM

FTC releases second interim staff report on prescription drug middlemen: Report finds PBMs charge significant markups for cancer, HIV, and other critical specialty generic drugsFTC press release; by FTC staff; 1/14/25Staff’s latest report found that the ‘Big 3 PBMs’—Caremark Rx, LLC (CVS), Express Scripts, Inc. (ESI), and OptumRx, Inc. (OptumRx)—marked up numerous specialty generic drugs dispensed at their affiliated pharmacies by thousands of percent, and many others by hundreds of percent. Such significant markups allowed the Big 3 PBMs and their affiliated specialty pharmacies to generate more than $7.3 billion in revenue from dispensing drugs in excess of the drugs’ estimated acquisition costs from 2017-2022. The Big 3 PBMs netted such significant revenues all while patient, employer, and other health care plan sponsor payments for drugs steadily increased annually, according to the staff report. Key Findings include:

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Transforming care: Spencer Health Solutions and Pharmerica partner to simplify medication management and improve lives

01/23/25 at 03:00 AM

Transforming care: Spencer Health Solutions and Pharmerica partner to simplify medication management and improve lives The MarCom Journal, Morrisville, NC; by Leigh White, PharMerica and Daphne Earley, Spencer Health Solutions; 1/21/25In a move set to redefine how medication is managed, Spencer Health Solutions (SHS), a leader in innovative healthcare technology, and PharMerica, one of the nation’s largest and most trusted long-term care pharmacy services provider, are joining forces. This transformative partnership aims to make managing medications easier and more reliable for individuals with complex medication needs, senior living communities, and payers nationwide. ... Spencer Health Solutions (SHS) is dedicated to transforming medication management through innovative healthcare technology. ... PharMerica ... serves the long-term care, senior living, hospital, home infusion, hospice, behavioral, specialty and oncology pharmacy markets. 

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North Augusta hospice nurse arrested after allegedly using fake prescriptions

01/23/25 at 03:00 AM

North Augusta hospice nurse arrested after allegedly using fake prescriptions Aiken Standard, Aiken, SC; by Matthew Christian; 1/22/25 A North Augusta hospice nurse has been arrested after allegedly acquiring prescription drugs with fake prescriptions. South Carolina Bureau of Drug Control agents arrested Amy Elizabeth Strand, 44, on Jan. 17, according to an Aiken County Sheriff's Office booking report. Strand obtained lorazepam 2 mg tablets from the North Augusta Kroger on June 22, 2024, Agent B.A. Stafford said in a warrant. ... To get the pills, Strand called in a fake prescription in the name of a patient under her care, Stafford continued. ... Strand has been charged with three counts of obtaining a controlled substance by fraud and one count of attempting to obtain a controlled substance by fraud. 

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DEA unveils long-overdue special registration for telemedicine in proposed rule

01/23/25 at 02:00 AM

DEA unveils long-overdue special registration for telemedicine in proposed ruleThe National Law Review; by Marika Miller, Nathan A. Beaver of Foley & Lardner LLP; 1/21/25 In the final days of the Biden administration, the Drug Enforcement Administration (DEA) released a proposed rule that would allow practitioners with a Special Registration to prescribe Schedule III-V, and in limited circumstances Schedule II, controlled substances via telemedicine. Practitioners with a Special Registration would still need to obtain a DEA registration in each state where they prescribe or dispense controlled substances. However, the proposed rule establishes a limited, less expensive State Telemedicine Registration as an alternative to the traditional DEA registration. The proposed rule imposes several obligations on practitioners with Special Registrations when they prescribe controlled substances via telemedicine.  [Click on the title's link to continue reading.]

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Justice Department sues Walgreens over alleged part in opioid crisis

01/22/25 at 03:00 AM

Justice Department sues Walgreens over alleged part in opioid crisis Becker's Hospital Review; by Madeline Ashley; 1/17/25 The Justice Department on Jan. 16 filed a civil complaint against Walgreens Boots Alliance and its subsidiaries alleging unlawful dispensation of millions of prescriptions in violation of the Controlled Substances Act. The complaint, filed in the U.S. District Court for the Northern District of Illinois, also alleges that Walgreens sought reimbursements from federal health programs in violation of the False Claims Act, according to a Jan. 17 news release. The Justice Department alleges that Walgreens knowingly filled millions of invalid controlled substance prescriptions since August 2012, including excessive opioid quantities, early refills and a "dangerous and abused combination of drugs" ... The complaint suggests pharmacists at Walgreens filled the prescriptions "despite clear red flags" indicating the prescriptions were likely unlawful, ignoring other internal data and evidence from pharmacists about dispensing unlawful prescriptions. 

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Enclara Pharmacia announces patient record integration with FireNote Hospice EMR

01/22/25 at 03:00 AM

Enclara Pharmacia announces patient record integration with FireNote Hospice EMR NCN - Nebraska News Channel; Business Wire Press Release; 1/21/25 Enclara Pharmacia, ... [a national] pharmacy solutions provider for the hospice and palliative care sectors, announces the launch of a new interface with FireNoteTM, an innovative hospice electronic medical record (EMR) platform. This integration enables patient demographics and medications to flow seamlessly from FireNote to Enclara’s E3 ProTM medication management system. The new software interface enables timely admissions and medication access for patients while reducing the administrative burden on nurses, a key priority for both Enclara and FireNote.“ 

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