How to prevent delirium by improving sleep for patients with serious illness

How to prevent delirium by improving sleep for patients with serious illness
CAPC blog; by Jeremy M. Hirst; 6/11/25
A palliative care psychiatrist shares eight behavioral interventions to improve sleep—and offers guidance on prescribing pharmacological treatments. Sleep is essential for rest and repair, but for many patients with serious illness, getting quality sleep is a struggle. Poor sleep can compromise functional status and contribute to or exacerbate the risk of delirium—a concern that's both commonly reported by patients and supported by research. As clinicians, we must address sleep to help prevent delirium, as it directly impacts mental clarity, healing, and quality of life. In this blog, I share behavioral interventions I've used to help patients improve sleep and discuss when pharmacological treatments may be appropriate.