Literature Review

Oncology-embedded supportive care and end-of-life outcomes: a comparative study of hospice-eligible Muslim patients with cancer and non-cancer diagnoses Supportive Care in Cancer; by Manahil Imran, Basel Ghurm Alshehri, Muhammad Ali Akhtar, Raafey Imran, Umar Iqbal, Maryam Imran, Aaliyaan Iqbal, Ibrahim M. Imran, Ibrahim T. Malik, Tabindeh Jabeen Khalid, Mohsin Iqbal, Belal Mohammad Sharaf, and Imran Khalid; 3/24/26 ... Conclusions: An oncology-embedded supportive care model in a Muslim-majority setting was associated with earlier transitions to comfort-focused care and less aggressive end-of-life interventions among hospice-eligible cancer patients. The contrast with non-cancer patients highlights the importance of structured supportive care integration and demonstrates that models adapted to cultural and religious contexts can effectively support comfort-focused care.

End-of-life care planning for individuals with special needsJD Supra; by Chamblis, Bahner & Stphel, P.C.; 3/23/26 Takeaways

HMN 2026: How Nursing’s moral agency cannot be outsourced to AI Health Medicine Network; by George Demiris, PhD, Patricia Brennan, PhD. Oonjee Oh, MSN, and Sang Bin You, MSN; 3/24/26 ... Recommendations for health  systems: The article emphasizes that nurses must not be passive users of technology but active leaders in its design and implementation. To preserve the public’s trust, the authors offer several critical recommendations.

Trauma-informed palliative care: A systematic scoping review of evidence sources describing concepts relevant to an emerging field of practice Palliative Medicine; by Rebecca Salama, Jane Simpson, Fiona J. R. Eccles, Maddy French; 3/23/26 Background: Trauma-informed palliative care aims to improve end-of-life experiences by recognising and responding to the presence of psychological trauma. While many practitioners support the approach, they also acknowledge the need to build a stronger evidence base.Results: ... the review identified a substantial body of evidence that describes concepts relevant to its approach. These findings provide a valuable starting point for future research.

What we get wrong about comfort at the end of life: Jennifer Martnick Cleveland.com, Cleveland, OH; by guest columnist Jennifer Martnick; 3/22/26 When people hear the word comfort in the context of serious illness or the end of life, they often picture something passive. A quiet room. Soft blankets. And a sense that medical care has somehow stepped back. That misunderstanding is one of the most persistent myths in health care. Comfort care is not about doing less. In many ways, it requires more skill, more attention and more presence than almost any other kind of medicine. At Reserve Care (formerly Hospice of the Western Reserve), comfort care means active, expert care delivered by clinicians trained to manage pain, ease symptoms and support the emotional and spiritual needs of patients and families facing serious illness.

Identifying key components of neuropalliative care fellowship using nominal group techniqueJournal of Pain & Symptom Management; by Sachi Y Gianchandani, Jocelyn M Jiao, Kwame O Adjepong, Yaowaree L Leavell, Jessica M Besbris, Neha M Kramer, Joel N Phillips, Paul M Vermilion; 2/26There is no standardized curriculum for neurology-focused palliative care training. An adapted nominal group technique (NGT) was used to collect and rank responses to 2 key questions: "In designing the ideal dedicated neuropalliative care clinician training experience, what core components should be included?" and "When a general palliative care fellowship has a neurologist in their program, how could the program/program director potentially tailor the year to their unique needs?" For both key questions, the top-ranked responses included: dedicated outpatient neuropalliative care experience, mentorship from faculty with expertise in neuropalliative care, and a core didactic curriculum that includes neurology-specific content. Additionally, appropriateness for certification in hospice and palliative medicine was identified as crucial.

Centering end-of-life care around what matters most: Goal-of-care discussions drive earlier hospice access Cleveland Clinic; features Laura Hoeksema, MD, MPH, FAAHPM; 3/10/26 Hospice experts help those with incurable disease maintain autonomy, reduce trauma and gain symptom relief. Yet studies show that the median length of stay in hospice before death is roughly 19 days. What can care teams do to ensure that patients and their families have access to this appropriate end-of-life care? As the Medical Director of Cleveland Clinic Hospice, Laura Hoeksema, MD, MPH, FAAHPM, and her team support physicians and patients in navigating this journey. ...

Facing death as a doctor: Knowledge vs natureMedscape; by Sarah Amandolare; 3/12/26 The decision to enroll her father in hospice care came easily for Janet Abrahm, MD. Abrahm, a palliative care doctor and former oncologist, helped her father — an internist who died of prostate cancer at home — understand the program’s benefits, such as family bereavement services, and that he could be readmitted to the hospital if needed. “Most doctors don’t know that,” said Abrahm, who is also a professor of medicine at Harvard Medical School in Boston and the author of Comprehensive Guide to Supportive and Palliative Care for Patients with Cancer. “They think it’s a one-way street, I imagine — that you put somebody in hospice and then that’s it. ... The level of engagement physicians have with death in their practice may inform how they want to die — and how they counsel loved ones facing a serious illness. But a new study suggests even as they face end-of-life decisions through the lens of their expertise, physicians can also be swayed by the same financial, familial, and existential burdens afflicting their patients. 

Antibiotics in hospice: Applying the four-quadrant approach to improve patient-centered care Oxford Academic | Clinical Infectious Diseases; by Patrick D. Crowley, Karen M. Meagher, Amelia K. Barwise; 3/5/26The use of antibiotics in the hospice setting is complicated by differing patient goals, elevated side effects, and limited information regarding effectiveness. Here, we describe a case and apply the four-quadrant approach (4QA). This includes analyzing the case through the lenses of (1) medical indications related to improving function and reducing symptoms; (2) patient preferences ...; (3) quality-of-life factors that include managing infectious symptoms versus antibiotic side effects; and (4) contextual features, which include antimicrobial resistance concerns and cost considerations. Antibiotics may be beneficial in some cases and should not be denied to patients enrolled in hospice care. More robust evidence-based information about outcomes is needed to inform discussions at the time of enrollment. Applying the 4QA to a case can help determine the best approach for each individual patient.

Corticosteroid use and risk of adverse events in metastatic hormone-sensitive prostate cancerThe Prostate; by Umang Swami, Qiujun Shao, Tamuno Alfred, Maelys Touya, Frank Cao, Pinal Kamdar, Jasmina Ivanova, Johanna Celli, David Nimke; 2/26Among the approved therapies for metastatic hormone-sensitive prostate cancer (mHSPC), abiraterone and docetaxel are administered concomitantly with corticosteroids. This study evaluated the association between corticosteroid use and risk of adverse events among patients with mHSPC. Our findings suggest that patients exposed to corticosteroids are at increased risk of adverse events, hospitalization, and death. As not all mHSPC treatments require concomitant use of corticosteroids, these findings may help to inform treatment decision-making.

What does moral agency mean for nurses in the era of artificial intelligence?Hastings Center Report; by Connie M Ulrich, Oonjee Oh, Sang Bin You, Maxim Topaz, Zahra Rahemi, Liz Stokes, Lisiane Pruinelli, George Demiris, Patricia Flatley Brennan; 2/26Being a moral agent was once thought to be an irreplaceable, uniquely human role for nurses and other health care professionals who care for patients and their families during illness and hospitalization. Today, however, artificial intelligence systems are often referred to as “artificial moral agents,” “agentic,” and “autonomous agents.” As these systems begin to function in various capacities within health care organizations and to perform specialized duties, the question arises as to whether the next step will be to replace nurses and other health care professionals as moral agents. Focusing primarily on nurses, this essay explores the concept of moral agency, asking whether it remains exclusive to humans or can be conferred on AI systems. We argue that AI systems should not supplant nurses’ moral agency, as patients come to hospitals or any other health care setting to be heard, seen, and valued by skilled professionals, not to seek care from machines.

"Black box" artificial intelligence for mortality prediction: a mixed- methods study of palliative care team, patient, and caregiver perspectives Annals of Palliative Medicine; by Beatrice Bridge, Ahmed Y Alasmar, Lauren Gunn-Sandell, Regina M Fink, Stacy M Fischer, Elizabeth Juarez-Colunga, Eric G Campbell, Matthew DeCamp; 2/26/26 Background: New artificial intelligence (AI)-based mortality prediction algorithms could support both patients' prognostic awareness and person-centered palliative care. ... Results: Among 53 interviewees, 18 expressed only concern about black box AI-based prognostication, 17 expressed only unconcern, and 18 interviewees expressed mixed sentiments. Reasons for concern related to: data transparency, mistrust of machines or their creators, patient-clinician communication, bias, and accuracy. Reasons for unconcern related to: inexplicability not unique to AI, greater accuracy, not using AI in isolation, trust in science, and being evidence-based. Notably, "accuracy" and "trust" appeared in both.