Literature Review
All posts tagged with “Clinical News | Pharmacy & Medication News | Pain Management News.”
Association between opioid use disorder and palliative care: a cohort study using linked health administrative data in Ontario, Canada
05/04/24 at 02:55 AMAssociation between opioid use disorder and palliative care: a cohort study using linked health administrative data in Ontario, CanadaCMAJ; by Jenny Lau, Mary M. Scott, Karl Everett, Tara Gomes, Peter Tanuseputro, Sheila Jennings, Rebecca Bagnarol, Camilla Zimmermann and Sarina R. Isenbergl; 4/29/24Background: People with opioid use disorder (OUD) are at risk of premature death and can benefit from palliative care. We sought to compare palliative care provision for decedents with and without OUD.Conclusion: We identified important differences in palliative care provided at the end of life between people with and without OUD. People with OUD were less likely to receive palliative care despite accessing palliative care earlier, which may reflect their end-of-life illness trajectories and underlying structural vulnerability that may prompt them to receive palliative care primarily in acute care. Health care providers should receive training in palliative care and addiction medicine to support people with OUD.
AI could play role in preventing prescribing of unnecessary drugs in older adults
04/26/24 at 03:00 AMAI could play role in preventing prescribing of unnecessary drugs in older adults McKnights Senior Living, by Kristen Fischer; 4/22/24 A new study finds that artificial intelligence could encourage doctors to stop prescribing drugs that aren’t necessary — especially in older adults, who tend to be on multiple medications. The report was published 4/18 in the Journal of Medical Systems. More than 40% of older adults are taking five or more prescription medications, a rate that raises their risk for potentially harmful drug interactions. ... AI isn’t a perfect tool compared with having an actual doctor. For instance, it tended not to pay much attention to a person’s pain level, suggesting that the patient stop taking pain medications but not others for clinical ailments such as high cholesterol or high blood pressure, the authors reported.
Comparative effectiveness of acupuncture vs massage for relieving pain in patients with advanced cancer
04/19/24 at 03:00 AMComparative effectiveness of acupuncture vs massage for relieving pain in patients with advanced cancer The ASCO Post; by Jun J. Mao, MD, MSCE and Andrew S. Epstein, MD; 4/17/24... The IMPACT study was conducted at Memorial Sloan Kettering Cancer Center and regional sites in New York, New Jersey, and Florida to evaluate the long-term comparative effectiveness of acupuncture vs massage for pain in patients with advanced cancer. ... The primary outcome—change in worst pain intensity score from baseline to 26 weeks—was measured using the Brief Pain Inventory (BPI ranging from 0–10; higher numbers indicate worse pain intensity or interference). The secondary outcomes included fatigue, insomnia, and quality of life. ... To use these therapies, it is important to seek credentialed practitioners who have training or experience in working with patients who have cancer.
Virtual reality therapy offers ‘sustained improvement’ in cancer-related pain
04/10/24 at 03:00 AMVirtual reality therapy offers ‘sustained improvement’ in cancer-related pain Healio, by Josh Friedman; 4/8/24 Individuals with cancer reported significantly reduced pain immediately following a 10-minute virtual reality (VR) session, study results published in Cancer showed. The findings from the randomized trial suggest that pain reductions associated with VR use are sustainable for up to 24 hours and produced a reduction in pain bothersomeness and destress, according to researchers.
Neuropsychiatric effects associated with opioid-based management for palliative care patients
04/05/24 at 03:00 AMNeuropsychiatric effects associated with opioid-based management for palliative care patients
Expanding the use of continuous sedation until death and physician-assisted suicide
03/29/24 at 03:00 AMExpanding the use of continuous sedation until death and physician-assisted suicide The Journal of Medicine & Philosophy: A Forum for Bioethics and Philosophy of Medicine; by Samuel H Lipuma and Joesph P Demarco; 3/27/24 The controversy over the equivalence of continuous sedation until death (CSD) and physician-assisted suicide/euthanasia (PAS/E) provides an opportunity to focus on a significant extended use of CSD.
Hospice & Palliative Care Handbook: Quality, Compliance, and Reimbursement, 4th Edition
03/29/24 at 03:00 AMHospice & Palliative Care Handbook: Quality, Compliance, and Reimbursement, 4th Edition McGraw Hill - Access APN; textbook by Tina M. Marrelli and Jennifer Kennedy; 3/28/24 “Hospice & Palliative Care Handbook, Fourth Edition, is an invaluable resource for timely hospice regulatory and compliance information, documentation, care planning, and case management. It provides clear guidance for hospice managers, clinicians, and interdisciplinary group members. I have utilized Tina Marrelli’s home health and hospice handbooks to support training new clinical staff and students for decades and consider these resources to be the gold standard.” – Kimberly Skehan, MSN, RN, HCS-D, COS-C, Vice President of Accreditation - Community Health Accreditation Partner
Antibiotics in end-of-life care
03/29/24 at 03:00 AMAntibiotics in end-of-life care NEJM Journal Watch, by Abigail Zuger, MD; 3/27/24Antibiotics often are considered to be among the gentler and more comfort-oriented interventions in end-of-life care, certainly far less aggressive than intubation or last-ditch surgery. ... Still, antibiotics do entail their own costs in the form of toxicities and need for intravenous access, and liberal antibiotic use reliably worsens institutional and community drug-resistance profiles. ... A new review was written for infectious disease consultants but contains specific suggestions that should interest both generalists and other subspecialists caring for dying patients.
Fall prevention for the elderly: 13 strategies to keep them safe
03/29/24 at 03:00 AMFall prevention for the elderly: 13 strategies to keep them safe U.S. News & World Report, by Claire Wolters, ed. by Christine Comizion, MPH; 3/26/24Falls are the leading cause of injury in adults 65 and older – with reports showing about 14 million adults fall each year, according to the Centers for Disease Control and Prevention. ... According to the CDC, falls are also the leading cause of injury-related death in the 65-and-older population – and the fall death rate is growing.Here's what to know about what increases risk for falls in older adults, and get familiar with fall prevention tips and safety measures that can help reduce the risk.Editor's Note: This U.S. News article primes the pump. Preventing falls matters especially for vulnerable hospice patients as their disease progresses, and as they and/or family want the person to be as mobile as possible. What do your Incident Reports tell you about falls? What falls-specific education do you provide for your interdisciplinary teams? On-call staff? Family caregivers? Volunteers? What QAPI programs have addressed falls?
Incurable but not hopeless: How hope shapes patients’ awareness of their advanced cancer prognosis
03/26/24 at 03:00 AMIncurable but not hopeless: How hope shapes patients’ awareness of their advanced cancer prognosis The Conversation, by Jean Mathews and Michael Brundage; 3/24/24Hope is defined as the expectation of achieving a future good. Patients with cancer, whether it is curable or not, prioritize cure as their highest hope. ... Previous research indicates that less than half of patients with incurable cancer are aware of their prognosis. This is often attributed to a failure of communication. ... In the context of advanced cancer, the relationship between hope and hopelessness is balanced by acceptance, which can re-direct hope to new goals beyond cure, such as hope for connection with others and enjoyment of daily pleasures.
4 things nobody tells you about watching a loved one die of cancer
03/26/24 at 03:00 AM4 things nobody tells you about watching a loved one die of cancer The New York Post; by Jessica Ariel Wendroff; 3/23/24 ... “The surgery was successful. However, tests after the operation found cancer had been present,” the Princess of Wales, 42, revealed in a bombshell videotaped statement Friday. ... While the royal insisted she is “well and getting stronger every day,” other patients’ real pain begins when the cancer has spread too far and chemotherapy and radiation no longer work, so doctors stop treatment. As the daughter of a Stage 4 bladder cancer patient, I’ve empirically learned four realities that people usually don’t talk about ...
Frailty needs to be a factor in drug development, proposed guidelines suggest
03/21/24 at 03:30 AMFrailty needs to be a factor in drug development, proposed guidelines suggest McKnights Long-Term Care News, by Kristen Fischer; 3/20/24A new report on strategies for geriatric drug development and assessment determined that drugs need to consider age as well as other factors that older adults face such as cognitive impairment, frailty and polypharmacy. This is according to the International Union of Basic and Clinical Pharmacology (IUPHAR) Geriatric Committee, which published the report. The strategies specifically focused on integrating frailty as a factor in drug development. The report, published in the Journal of the American Geriatrics Society earlier this month, includes 12 principles pertaining to frailty in reference to drug development. The recommendations include measuring frailty at the start of when a person goes on a drug they’ll likely take regularly.
Health care utilization and opioid use in patients receiving an integrated palliative care intervention for treatment of head and neck cancer compared to a historical control
03/20/24 at 03:00 AMHealth care utilization and opioid use in patients receiving an integrated palliative care intervention for treatment of head and neck cancer compared to a historical control Elsevier, International Journal of Radiation; by F. Rizwan. C. D'Avella, M. Albert, T. King, B. Egleston, T.J. Galloway, M. Chwistek, C. Fang, A. El-jawahri, J.R. Bauman; online access for 4/1/24 release Patients receiving chemoradiation therapy (CRT) for head and neck cancer (HNC) can develop significant symptomology (odynophagia, malnutrition) resulting in frequent hospitalizations and decreased quality of life (QOL) and continue to have chronic symptoms such as dysphagia and/or pain. The integration of a palliative care (PC) team during CRT has the potential to address the high symptom burden and improve QOL.
Palliative Care as ‘Personalized Medicine’
03/19/24 at 03:00 AMPalliative Care as ‘Personalized Medicine’Hospice News, by Jim Parker; 3/18/24The term “personalized medicine” is often used to describe health needs based on a patient’s genetics. However, more stakeholders are applying the term to palliative care. Personalized medicine is a step away from a “one-size-fits-all” approach to health care. The model uses information gathered from a patient’s genome to plan for care, treatment and services, and to some extent, predict a likely health trajectory, according to the National Human Genome Research Institute, part of the National Institutes of Health.
Preventing adverse drug events in hospice care
03/18/24 at 03:00 AMPreventing adverse drug events in hospice care Hospice News, by Holly Vossel; 3/15/24 Documentation errors and a fragmented health system pose the greatest risks for adverse drug events among hospices. ... Evaluating these risks involves having solid medication reconciliation processes in place — both at the time of a patient’s admission and throughout their end-of life care experience, according to Mary Lynn McPherson, professor and executive program director of advanced post-graduate education in palliative care at the University of Maryland’s School of Pharmacy. McPherson also serves on the board of the American Academy of Hospice and Palliative Medicine (AAHPM).
ACC updates HFrEF Decision Pathway, reinforcing the Four Pillars of Therapy
03/13/24 at 03:00 AMACC updates HFrEF Decision Pathway, reinforcing the Four Pillars of Therapy
Description and outcomes of a palliative care pharmacist-led Transitions of Care program
03/11/24 at 02:00 AMDescription and outcomes of a palliative care pharmacist-led Transitions of Care program J Palliat Med, by Connor McCormick, Mamta Bhatnagar, Robert M Arnold, Maria Felton Lowry; 3/6/24Background: Patients with palliative care needs are at high risk of medication errors during transitions of care (TOC). Palliative Care Pharmacist Interventions surrounding Medication Prescribing Across Care Transitions (IMPACT) program was developed to improve the TOC process from hospital to community setting for cancer patients followed by palliative care. Conclusion: Our pilot study demonstrates that integrating a pharmacist in TOC for seriously ill patients is feasible and valuable.
Johns Hopkins study reveals medical marijuana lowers pain, hospital visits
03/07/24 at 02:00 AMJohns Hopkins study reveals medical marijuana lowers pain, hospital visits BNN, by Wojciech Zylm; 3/5/24Recent research highlights significant improvements in well-being for cannabis users, offering hope for those with chronic illnesses. The study showcases a potential shift in the perception and utilization of medical cannabis in healthcare.
Subcutaneous patient-controlled analgesia in home-based palliative care: "It's as straightforward as pushing a button, right at my fingertips"
02/28/24 at 03:00 AMSubcutaneous patient-controlled analgesia in home-based palliative care: "It's as straightforward as pushing a button, right at my fingertips" J Pain Palliat Care Pharmacother, by Miguel Julião, Patrícia Calaveiras, Eduardo Bruera, Paulo Faria de Sousa; 2/26/24Subcutaneous patient-controlled analgesia (SCPCA) in home-based palliative care is a potentially valuable option for providing effective pain relief to some patients, particularly when conventional analgesic approaches prove ineffective or are refused.
Exploring the role of medicinal cannabis in palliative care
02/22/24 at 03:00 AMExploring the role of medicinal cannabis in palliative careMicrodose, by Keith Fiveson; 2/19/24Palliative care is a crucial aspect of healthcare, aiming to enhance the quality of life for patients facing incurable illnesses. Within this context, the use of medicinal cannabis (MC) has emerged as a potential avenue for addressing various symptoms and improving overall well-being. This article delves into a systematic review conducted by Marjan Doppen and colleagues, which examines the current evidence surrounding MC’s effects and potential harms in palliative care settings.
Reimagining end-of-life care: Balancing polypharmacy, treatment modification, and quality of life in advanced cancer patients
02/19/24 at 03:00 AMReimagining end-of-life care: Balancing polypharmacy, treatment modification, and quality of life in advanced cancer patientsBNN, by Mahnoor Jehangir; 2/15/24In a recent groundbreaking study, researchers have illuminated the complexities surrounding polypharmacy and the prescription of potentially inappropriate medications (PIMs) to patients at the end of their lives, particularly those battling advanced cancer. This investigation, involving a cohort of 265 older adults, sheds light on the nuanced challenges and critical decisions faced by healthcare providers in managing the delicate balance between treatment efficacy and quality of life for terminally ill patients.
Strategies for positive change in opioid prescribing
02/06/24 at 04:00 AMStrategies for positive change in opioid prescribingPharmacy Times; 2/1/24This is a video synopsis/summary of a Practice Pearls featuring Ryan Haumschild, PharmD, MS, MBA, CPEL; Megan Mitchell, PharmD, MS; Stephanie Abel, PharmD, BCPS; and Jennifer Grate, CPhT. Haumschild discusses the importance of positive change in opioid stewardship.
Study testing new strategy for spotting, managing pain in dementia patients
02/05/24 at 04:04 AMStudy testing new strategy for spotting, managing pain in dementia patients McKnights Long-Term Care News, by Kimberly Marselas; 2/1/24Up to 80% of dementia patients living in nursing homes also experience pain, but many struggle to communicate their symptoms. A new, $2.1 million study aims to test recently revised guidelines for staff members tasked with detecting and managing that pain. ... Barbara Resnick, PhD, RN, professor and associate dean for research at the University of Maryland School of Nursing, will lead the project at 12 nursing homes over the next five years.
Cancer facts & figures 2024
02/05/24 at 04:00 AMCancer facts & figures 2024American Cancer Society; 2024Cancer Facts & Figures 2024 is an educational companion for Cancer Statistics 2024, a scientific paper published in the American Cancer Society journal, CA: A Cancer Journal for Clinicians. These annual reports provide:
A pathophysiological approach for selecting dedications to treat nociceptive and neuropathic pain in servicemembers
02/05/24 at 04:00 AMA pathophysiological approach for selecting medications to treat nociceptive and neuropathic pain in servicemembersMil Med, by Khan Thi Nguyen, Daniel W Beauchamp, Reginald B O'Hara; 1/31/24The prevalence of chronic pain of service members (SMs) in the U.S. is estimated to be higher (roughly 31-44%) compared to that of civilian population (26%). This higher prevalence is likely due to the high physical demands related combat and training injuries that are not immediately resolved and worsen over time. Mental Health America reports that chronic pain can lead to other mental health conditions such as severe anxiety, depression, bipolar disorder, and post-traumatic stress disorder.