Alzheimer’s history on maternal side linked to higher disease risk, study finds

Alzheimer’s history on maternal side linked to higher disease risk, study finds 
McKnights Long-Term Care News; by Kristen Fischer; 6/17/24 
People with a history of Alzheimer’s disease on their mother’s side or both parents’ sides of the family had higher levels of amyloid plaques in their brains compared to those with fathers who had the disease, according to a study published Monday in JAMA Neurology. Increased amyloid, a biomarker for Alzheimer’s disease, was also found in those whose fathers had early onset of symptoms. But it wasn’t as high as in people who had higher amyloid on their mothers’ side of the family, the data showed. Mass General Brigham researchers used amyloid imaging on 4,413 cognitively unimpaired adults who were between 65 and 85.