Familial loss of a loved one and biological aging: NIMHD Social Epigenomics Program

08/03/24 at 03:45 AM

Familial loss of a loved one and biological aging: NIMHD Social Epigenomics Program 
JAMA Network Open; by Allison E. Aiello, PhD, MSAura Ankita Mishra, PhDChantel L. Martin, PhDBrandt Levitt, PhDLauren Gaydosh, PhDDaniel W. Belsky, PhDRobert A. Hummer, PhDDebra J. Umberson, PhDKathleen Mullan Harris, PhD; 7/29/24
Is the experience of losing a loved one associated with accelerated biological aging? In a cohort study of 3963 participants from the National Longitudinal Study of Adolescent to Adult Health, nearly 40% experienced the loss of a close relation by adulthood. Participants who had experienced a greater number of losses exhibited significantly older biological ages compared with those who had not experienced such losses. These findings suggest that loss can accelerate biological aging even before midlife and that frequency of losses may compound this, potentially leading to earlier chronic diseases and mortality.

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