Literature Review

All posts tagged with “Research News | Journal Article.”



Comparison of patients seen by an embedded social worker and nurse practitioner palliative care model in hospital medicine versus referral-based specialty palliative care and their acute care utilization outcomes

02/19/26 at 03:00 AM

Comparison of patients seen by an embedded social worker and nurse practitioner palliative care model in hospital medicine versus referral-based specialty palliative care and their acute care utilization outcomes Journal of Palliative Medicine; by Laura P Gelfman, Li Zeng, Keisha Bergland, Elizabeth Rizzo, Cheyenne Higgins, Claire Doucette, Krishna Chokshi, Emily Chai; 2/17/26 Background: Hospitalized patients with serious illness often face delayed or limited access to palliative care. Embedded hospital primary palliative care (HPPC), led by social workers and nurse practitioners, may deliver more timely, needs-based support compared with referral-based specialty palliative care (SPC). Conclusions: An embedded SW/NP-led palliative care model in hospital medicine improves access, reduces acute care use, and is sustainable over time. This approach supports timely, culturally sensitive, needs-based palliative care and may be scalable for hospital-based delivery.

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About 1 in 15 older Emergency Department patients are prescribed high-risk medications

02/17/26 at 03:00 AM

About 1 in 15 older Emergency Department patients are prescribed high-risk medications Medscape; edited by Gargi Mukherjee; 2/13/26 Analysis of over 16 million emergency department (ED) encounters revealed that about 1 in 15 (6.5%) older adults received potentially inappropriate medications (PIMs) at discharge. Prescription rates declined with advancing age, from 8.3% among patients aged 65-74 years to 1.8% among those aged 95 years or older. Skeletal muscle relaxants and first-generation antihistamines were the most commonly prescribed high-risk medications.

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Psychosocial oncology: The Omega Project

02/17/26 at 03:00 AM

Psychosocial oncology: The Omega Project Taylor & Francis | Death Studies; by Matthew Loscalzo and Linda A. Klein; 2/14/26This article reports on an interview with J. William Worden that focuses initially on the Omega Project (1968–1986) that studied end-of-life care. Worden explains the four phases of the project with specific populations, goals, and key concepts that emerged. The discussion then shifts to the development of psychosocial oncology and palliative care. Finally, Worden offers some thoughts on the development of the hospice movement in the United States, the role of religion in coping with mortality, coping with personal loss, and his advice to new medical or graduate students just starting out.

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Geographic and sociodemographic disparities in access to hospice in Pennsylvania

02/17/26 at 03:00 AM

Geographic and sociodemographic disparities in access to hospice in Pennsylvania American Journal of Hospice and Palliative Medicine; by Jacob Whitman, PhD, Dylan Nagy, MS, Harsheni Sudakar, BSPH, Coleman Drake, PhD, Lindsay Sabik, PhD, and Yael Schenker; 2/14/26 online ahead of print Results: In total, 2.3 million Pennsylvanians, or 17% of the state population, reside in census tracts classified as cold spots. Cold spots were concentrated in rural and socioeconomically disadvantaged regions. Compared with other tracts, cold spot tracts were lower income, less educated, older, more reliant on public insurance, and less racially diverse. Patterns were consistent when restricting to high quality hospice and nonprofit hospices. Conclusion: Geographic disparities in hospice access compound existing sociodemographic inequities. Addressing these inequities will require efforts to expand high-quality hospice availability in underserved communities.

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The global need for paediatric palliative care: the evolution of serious health-related suffering in children aged 0-19 years from 1990 to 2023

02/16/26 at 03:00 AM

The global need for paediatric palliative care: the evolution of serious health-related suffering in children aged 0-19 years from 1990 to 2023 The Lancet - Child & Adolescent Health; by Julia Downing, Felicia Marie Knaul, Xiaoxiao Jiang Kwete, Héctor Arreola-Ornelas, Nickhill Bhakta, William E Rosa, Lukas Radbruch, Julia Ambler, Stephen R Connor, Jinfeng Ding, Megan Doherty, Rui Gong, Richard Hain, Rut Kiman, Eric L Krakauer, Michael J McNeil, Oscar Méndez-Carniado, Marina Morais, Mary Ann Muckaden, Tania Pastrana, Marianne Phillips, Hongliang Tao, Michael Touchton, Valentina Vargas Enciso, Paul Vila, Afsan Bhadelia; online ahead of print March 2026 Our findings underscore the crucial need to expand access to high-quality palliative care services for children and adolescents, particularly in low-income and middle-income countries (LMICs). Our results also highlight the shift from decedent to non-decedent care needs associated with the substantial morbidity experienced by those living with their disease. Specific health-system policies to respond to the need for increased and higher-quality paediatric palliative care, especially interventions and medicines essential to address the unique palliative care needs of children, must be adequately funded to effectively reduce the avoidable burden of serious health-related suffering (SHS) among children.

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Assistive intelligence: A framework for AI-powered technologies across the dementia continuum

02/14/26 at 03:45 AM

Assistive intelligence: A framework for AI-powered technologies across the dementia continuumJournal of Ageing & Longevity; by Bijoyaa Mohapatra, Reza Ghaiumy Anaraky; 1/26While traditional [dementia] care models often focus on symptom management in later stages, emerging artificial intelligence (AI) technologies offer new opportunities for proactive and personalized support across the dementia trajectory. This concept paper presents the Assistive Intelligence framework, which aligns AI-powered interventions with each stage of dementia: preclinical, mild, moderate, and severe. These are mapped across four core domains: cognition, mental health, physical health and independence, and caregiver support. We illustrate how AI applications, including generative AI, natural language processing, and sensor-based monitoring, can enable early detection, cognitive stimulation, emotional support, safe daily functioning, and reduced caregiver burden. The paper also addresses critical implementation considerations such as interoperability, usability, and scalability, and examines ethical challenges related to privacy, fairness, and explainability.

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The impact of religious and spiritual care on parents or caregivers in pediatrics: A scoping review

02/14/26 at 03:40 AM

The impact of religious and spiritual care on parents or caregivers in pediatrics: A scoping reviewJournal of Health Care Chaplaincy; by Salvador Leavitt-Alcántara, Samantha Summers; 1/26This scoping review examines the literature on the impact of spiritual and religious care on parents or guardians of children admitted to high acuity pediatric hospital units. Results reveal themes of positive impact of spiritual or religious care on several components of parents/caregivers' in the areas of emotional coping, grief and bereavement, positive parental perception of the impact of chaplains in high acuity settings, and outside spiritual/religious guidance and support during the medical decision-making process.

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Sociodemographic disparities and impact of palliative care utilization during end-of-life hospitalizations in patients with gastric cancer

02/14/26 at 03:35 AM

Sociodemographic disparities and impact of palliative care utilization during end-of-life hospitalizations in patients with gastric cancerJournal of Palliative Medicine; by James Lee, Jasmine Lee, Rahul Tripathi, David Stein, Ballakur Rao, Daniel Jamorabo, Lisa Fisher; 1/26Gastric cancer is frequently diagnosed at an advanced stage and is associated with high symptom burden. Among 13,435 weighted hospitalizations [among gastric cancer patients who died during hospitalization] ..., 57.6% received palliative care. Black patients had 32% lower odds of receiving palliative care than White patients ... Higher palliative care use was associated with greater income, large hospitals, urban teaching hospitals, and private/other insurance. In adjusted analyses, palliative care was linked to a $36,240 reduction in hospital charges ..., with no significant difference in LOS [length of stay]. Palliative care was associated with higher odds of DNR status ... and lower odds of CPR, mechanical ventilation, transfusion, and vasopressor use.

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Difficult encounters: How to set boundaries in the context of structural inequities

02/14/26 at 03:30 AM

Difficult encounters: How to set boundaries in the context of structural inequitiesJournal of Pain & Symptom Management; by Carrie C. Wu, Erik K. Fromme; 1/26Difficult encounters between patients and clinicians impact all areas of medical care, yet how to manage them is not routinely taught in medical training. This paper presents a case of a patient with cancer who struggled with emotional outbursts and impulsive behaviors. In the context of the racial trauma and socioeconomic challenges that the patient also experienced, the team struggled with boundary setting. We will review both traditional and contemporary approaches to the management of difficult clinician-patient interactions, while also addressing some of the limitations of existing frameworks. We will explore the role of bias in boundary setting and make suggestions for individual-, team-, and system-level approaches.

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Presence experiences after loss: Prevalence and relational meaning in a diverse urban sample

02/14/26 at 03:25 AM

Presence experiences after loss: Prevalence and relational meaning in a diverse urban sampleOmega; Claire White, Anna Mathiassen, Ronald Fischer; 1/26Presence experiences-the sense that a significant person who has died is nearby or perceptible-are common after bereavement but remain underexamined in grief research. This study ... [revealed that] ... over two-thirds of participants reported having ever experienced a presence, with nearly half reporting at least one occurrence in the past two weeks. These experiences were most commonly reported as a general feeling of presence, rated as both significant and welcome. Participants frequently interpreted encounters as meaningful attempts at contact and preferred disclosing these experiences to close social connections rather than institutional figures. These findings highlight presence experiences as common, relationally shaped, and culturally interpreted aspects of bereavement.

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Direct care nursing as a career destination-A qualitative exploration of why nurses stay

02/14/26 at 03:20 AM

Direct care nursing as a career destination-A qualitative exploration of why nurses stayNursing Management; by Leach, Catherine T.; Whade, Jill J.; Horvick, Savannah G.; 1/26Intent to stay (ITS) is the best predictor of nurse turnover. Interventions aimed at combating turnover may be ineffective if they're developed without getting input from nurses to understand why they stay. A total of 18 clinical nurses were interviewed, and four major themes were identified: organizational culture, sense of belonging, leadership in action, and sustainability of bedside nursing. Conclusions: Integrating organizational culture, sense of belonging, leadership in action, and resources for direct care nursing will strengthen nurses' ITS and encourage nurses to pursue direct care nursing as a career destination.

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Palliative external beam radiation therapy for dysphagia in a 101-year-old man with esophageal adenocarcinoma

02/14/26 at 03:15 AM

Palliative external beam radiation therapy for dysphagia in a 101-year-old man with esophageal adenocarcinomaCureus; by Pericles J. Ioannides, Jester M. Odrunia, Gina N. Perez, Morgan Butow, Georg A. Weidlich; 1/26Esophageal adenocarcinoma in centenarians is rare, and treatment options in this age group are limited. We present the case of a 101-year-old male patient with symptomatic distal gastroesophageal junction (GEJ) adenocarcinoma who presented with progressive dysphagia, aspiration, and weight loss. The patient underwent palliative external beam radiation therapy (EBRT) ... targeting the obstructive esophageal mass with a margin using volumetric-modulated arc therapy (VMAT) technique. The treatment was well tolerated by the patient with no significant acute toxicity. After treatment, the patient reported clinically meaningful improvement in functional status, with improved swallowing, advancing from liquids to a soft diet, weight gain, and improved QoL. Moderate-dose palliative radiation can be a safe and effective treatment in a centenarian with obstructive GEJ adenocarcinoma, particularly when endoscopic interventions are not successful or durable.

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Understanding advance care planning among young adults: A theory-based examination using the Integrated Behavioral Model and Precaution Adoption Process Model

02/14/26 at 03:10 AM

Understanding advance care planning among young adults: A theory-based examination using the Integrated Behavioral Model and Precaution Adoption Process ModelJournal of Social Work in End-of-Life & Palliative Care; by Colette A. McAfee, Derek Cegelka, Victoria R. Wagner-Greene, Amy Wotring; 1/26This study examined predictors of ACP [advance care planning] behaviors among U.S. adults aged 18–35 (N = 614) using the Integrated Behavioral Model (IBM) and the Precaution Adoption Process Model (PAPM). ACP engagement was defined as completing a living will, designating a durable power of attorney for health care (DPAHC), and discussing wishes with a loved one. Most participants (68.6%) had not fully engaged in ACP. Regression analyses revealed that direct perceived norms, attitudes, and life experience with serious illness were significant predictors of intention to engage in ACP.  Personal or family experiences with life-threatening illness emerged as key motivators.

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[China] Progress in research on alleviating the symptoms associated with advanced cancer using Traditional Chinese Medicine

02/14/26 at 03:05 AM

[China] Progress in research on alleviating the symptoms associated with advanced cancer using Traditional Chinese MedicinePain Research & Management; by Chunmeng Jiao, Ting Zhang, Yachen Yang, Ruofan Zhang, Wenbo Liu, Yanqing Wang, Lei Huang; 1/26Advanced cancer continues to pose a substantial global challenge, with complex symptom burdens and limited therapeutic options. Traditional Chinese Medicine (TCM), grounded in holistic theory and the principles of syndrome differentiation, employs interventions such as herbal medicine, acupuncture, moxibustion, and acupoint‐based therapies to address both the malignancy and the patient’s overall functional status. Emerging evidence indicates that TCM may alleviate symptom clusters associated with advanced cancer, enhance quality of life, and potentially contribute to improved survival outcomes. This review synthesizes findings from the past decade on the role of TCM in advanced cancer care, with a focus on herbal decoctions, Chinese herbal injections, acupuncture—either alone or in combination with herbal therapy—moxibustion with adjuvant medication, and other external TCM modalities. Evidence is examined regarding their effects on cancer‐related pain, fatigue, gastrointestinal dysfunction, chemotherapy‐ and radiotherapy‐induced toxicities, and immune modulation.

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Advance care planning for patients with hematologic malignancies: A narrative review

02/14/26 at 03:05 AM

Advance care planning for patients with hematologic malignancies: A narrative reviewAmerican Journal of Hospice & Palliative Medicine; by Olivia M. Seecof; 1/26Advance care planning (ACP) completion rates are higher in patients with serious illness compared to the general population, however, ACP is overall under-utilized and sub-optimal, especially for patients with hematologic malignancies. This patient population can experience unique and significant physical and psychological symptoms due to their illness and the treatment, resulting in high rates of aggressive end of life care. This high healthcare utilization pattern often triggers ACP conversations and documentation, often facilitated by specialty palliative care clinicians. This review article examines existing literature about ACP for patients with hematologic malignancies with the intent to inform future prospective research to improve values-based patient care.

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Durable powers of attorney and death in the critical care unit

02/14/26 at 03:00 AM

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[Republic of Korea] P-1080. Multidrug-resistant organism status and its association with hospice use and end-of-life care patterns in patients with advanced cancer referred palliative care

02/14/26 at 03:00 AM

[Republic of Korea] P-1080. Multidrug-resistant organism status and its association with hospice use and end-of-life care patterns in patients with advanced cancer referred palliative careOpen Forum Infectious Diseases; by Jeong-Han Kim, Jiwon Yu, Ye Sul Jeung, Shin Hye Yoo, Jin-ah Sim, Bhumsuk Keam; 1/26Multidrug-resistant organisms (MDRO) are increasingly prevalent and may contribute to more aggressive healthcare utilization near the end-of-life, particularly among patients with advanced cancer receiving palliative care (PC). MDRO status was associated with significantly lower use of community-based hospice care, including inpatient hospice ... and home hospice ... It was also linked to more frequent deaths in tertiary hospitals ... and higher intensive care unit admissions ... and renal replacement therapy ... Medical costs were consistently higher in the MDRO group across all end-of-life trajectory before death.

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Experiences and knowledge of family caregivers providing end of life care to older adults at home

02/09/26 at 03:00 AM

Experiences and knowledge of family caregivers providing end of life care to older adults at home American Journal of Hospice and Palliative Medicine; by Delaney E. Knutson, BSN and Barbara St Marie, PhD, AGPCNP, FAANP, FAAN; 1/28/26 Conclusion: This scoping review highlighted the need for increased information for family caregivers regarding end-of-life care to reduce the challenges and burden for families caring for their older adult at home at end-of-life. Areas for improvement include increased support from family and friends, caregiver respite, increased education about caregiving, and improved communication between hospice programs and home caregivers. 

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From the iron lung to artificial intelligence: Integrating new technology into critical care

02/07/26 at 03:45 AM

From the iron lung to artificial intelligence: Integrating new technology into critical care American Journal of Critical Care; by Seo Yoon Lee, Alvin D. Jeffery; 1/26Artificial intelligence technology has emerged rapidly and is being incorporated into the health care delivery system as a new bedside tool. It is vital to maintain a human-centered approach, in which artificial intelligence serves as a tool to augment, not replace, the nuanced judgment of health care professionals. It is crucial to cultivate a critical mindset, continuously validating artificial intelligence outputs against clinical judgment. Integrating artificial intelligence into team workflows, developing clear ethical guidelines, and fostering collaboration between clinicians and data scientists are essential for successful implementation. By proactively preparing for the transition, the critical care community can harness artificial intelligence’s power to improve patient recovery and survival while ensuring that technology remains guided by human expertise and compassion.Assistant Editor's note: All of us in health care, not just those working in critical care, will be faced with decisions about how to incorporate AI into our work. It will likely become an invaluable tool in our day-to-day lives. But AI can only give us ideas, suggestions and enhanced knowledge. It cannot hold the hand of a dying patient or comfort the loved ones who bear witness. Only we can offer the CARE in health care. Empathy, humanness and critical thinking can come only from us.

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Medical Aid in Dying and our ethical duties—Call to action

02/07/26 at 03:40 AM

Medical Aid in Dying and our ethical duties—Call to actionJAMA Health Forum; by Yesne Alici, Liz Blackler, Julia Danielle Kulikowski, Amy Scharf; 1/26Medical aid in dying (MAID) is legal in 11 US states and Washington, DC, and is being actively considered in 18 additional states ... In all jurisdictions where MAID is legal, hospital systems have the option to opt out of providing MAID services but are legally obligated to share information about where patients can access resources. We maintain that all hospital systems and individual clinicians have an ethical responsibility to go beyond simply sharing information. Patients are going to ask about MAID, and institutions are ethically obligated to establish comprehensive policies that empower and encourage their clinical staffs—primarily physicians but also nurses and advanced practice clinicians—to purposefully and thoughtfully respond. Here, we describe the experience of our institution, Memorial Sloan Kettering Cancer Center (MSK), in developing policies and procedures to fulfill this responsibility and highlight lessons for other health care organizations and oncology practices seeking to accomplish similar goals.

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Later-life friendship in advance care planning: Variation by marital status and gender

02/07/26 at 03:35 AM

Later-life friendship in advance care planning: Variation by marital status and genderResearch on Aging; Zheng Lian, Lucie Kalousová; 1/26Friendship is an understudied social context in research on advance care planning (ACP).  Multivariable logistic regressions show that having any friends is associated with greater odds of AD [advance directives] and EOL [end-of-life] discussions. The positive association between emotional support from friends and EOL discussions is more pronounced among never married men, compared to both married individuals and never married women. These findings highlight friendship as a salient social context associated with ACP engagement, particularly among never married men.

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Preparing for the inevitable: a scoping review of death and dying education in U.S. medical schools

02/07/26 at 03:30 AM

Preparing for the inevitable: a scoping review of death and dying education in U.S. medical schoolsAcademic Medicine; by Logan Patterson, Autumn Decker, Angelique King, Anna Roman, Cory Bolkan, Raven H Weaver; 1/26There remains a sizeable gap in evidence-based medical education related to knowledge, skills, and abilities pertaining to end-of-life care. The authors offer next steps for developing, implementing, and measuring evidence-based interventions to improve end-of-life care competency. The authors advocate for continued implementation of evidence-based educational interventions, regardless of anticipated specialty area, throughout all preclinical and clinical years.

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A scoping review on aphasia and technology: Exploring mechanisms enhancing quality of life

02/07/26 at 03:25 AM

A scoping review on aphasia and technology: Exploring mechanisms enhancing quality of lifeQuality of Life Research; by Grace E. Terry, Cassondra Wilson, Gillian Anderson, Stacy M. Harnish; 1/26 People with aphasia are at an increased risk for reduced quality of life (QoL) because of their change in communication abilities. The present study aims to review the current evidence supporting assistive technology as a tool to improve QoL for people with aphasia, while investigating the various mechanisms technology may impact that lead to increased QoL for people with aphasia. This review emphasizes the role mechanisms such as self-management, social interaction, and virtual communication play in improving QoL for people with aphasia, while emphasizing the role technology plays in impacting the function of these mechanisms.  However, for this assistive technology to be impactful, it must be person centered and thoroughly trained based on the current body of evidence.

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Researchers identify new blood markers that may detect early pancreatic cancer; NIH-funded, four-marker panel could one day help catch one of deadliest cancers at more treatable stages.

02/07/26 at 03:20 AM

Researchers identify new blood markers that may detect early pancreatic cancer; NIH-funded, four-marker panel could one day help catch one of deadliest cancers at more treatable stagesNIH press release; 1/30/26National Institutes of Health (NIH)-supported investigators have developed a blood test to find pancreatic ductal adenocarcinoma, one of the deadliest forms of cancer. The new test could improve survival rates from pancreatic cancer, which tends to be diagnosed at late stages when therapy is less likely to be effective. The findings were published in Clinical Cancer Research. Overall, only about 1 in 10 pancreatic cancer patients survive more than five years from diagnosis. However, experts expect that when the cancer is found and treated at an earlier stage, survival would improve. While finding the cancer early is key, there are no current screening methods to do so.

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EV0034 Palliative pain relief: A case study of high-frequency spinal cord stimulation in an end-of-life cancer patient

02/07/26 at 03:15 AM

EV0034 Palliative pain relief: A case study of high-frequency spinal cord stimulation in an end-of-life cancer patientNeuromodulation: Technology at the Neural Interface; P. Majedi, Dominic Bailey; 1/26A significant proportion of patients with cancer will experience cancer-related pain at some point during their illness. The treatment approach for cancer-related pain is often multifaceted and may necessitate the use of advanced interventional methods, including spinal cord stimulation (SCS). Recent studies have demonstrated the utility and efficacy of SCS techniques in the treatment of cancer-related pain and chemotherapy induced neuropathy. Here, we present a case report on a patient receiving high frequency SCS at 10 kHz for end-stage cancer-related pain.

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