Literature Review

All posts tagged with “Research News | Journal Article.”



Training and practice gaps in nursing home palliative care: A cross-sectional study

09/09/25 at 03:00 AM

Training and practice gaps in nursing home palliative care: A cross-sectional study Journal of the American Geriatrics Society (AGS); by Manali Saraiya, Molly A. Nowels, Rose L. Carlson, Jerad H. Moxley, Catherine A. Riffin, Evan Plys, M. Carrington Reid, Isabella Hastings, Taimur Mirza, Ronald D. Adelman, Daniel Shalev; 9/7/25 We conducted a cross-sectional survey of clinical employees (N = 398) at seven NHs within a single integrated health system in New York State to (1) gauge attitudes toward and knowledge about palliative care, (2) estimate the extent of engagement with advance care planning, and (3) elicit perceptions of the most valuable components of palliative care for NH residents. ... Despite support for palliative care, gaps in knowledge and clinical engagement persist and vary by discipline. Discipline-tailored training and program design may improve palliative care delivery in NHs and help ensure more consistent, value-aligned care for residents with serious illness.

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[France] Palliative care for solid organ transplant candidates and recipients: A scoping review

09/06/25 at 03:55 AM

[France] Palliative care for solid organ transplant candidates and recipients: A scoping reviewTransplantation Reviews; by Liesbet Van Bulck, Fiona Ecarnot, Mathilde Giffard; 8/25Solid organ transplant patients experience high morbidity and mortality before and after transplantation. International guidelines recommend integrating palliative care into the management of patients with advanced organ failure, including transplant candidates and recipients, as it supports advance care planning, enhances communication and improves symptom management. This scoping review shows that palliative care for organ transplant has received little attention heretofore.

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Estimating the predictability of questionable open-access journals

09/06/25 at 03:45 AM

Estimating the predictability of questionable open-access journalsScience Advances; by Han Zhuang, Lizhen Liang, Daniel E. Acuna; 8/25Questionable journals threaten global research integrity, yet manual vetting can be slow and inflexible. Here, we explore the potential of artificial intelligence (AI) to systematically identify such venues by analyzing website design, content, and publication metadata. Evaluated against extensive human-annotated datasets, our method achieves practical accuracy and uncovers previously overlooked indicators of journal legitimacy... Our study defines “questionable open-access journals” as journals violating the best practices outlined by the Directory of Open Access Journals (DOAJ) and showing indicators of low editorial standards.Publisher's note: The authors use AI to evaluate open-access journals adherence to best publishing practices - an interesting use of AI that could be applied to many other settings. The list of open-access journals can be found here.

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Can AI simplify surgical instructions as effectively as humans? Enhanced surgical instructions using large language models

09/06/25 at 03:40 AM

Can AI simplify surgical instructions as effectively as humans? Enhanced surgical instructions using large language modelsJAMA Network / JAMA Surgery / Research Letter; by Maxwell Sahhar, Joseph E. Nassar, Anne-Emilie Rouffiac, Kaitlyn Crow, Manjot Singh, Michael J. Farias, Bassel G. Diebo, Alan H. Daniels; 8/25Human authors and a chatbot improved documents from a 9th-grade to 6th-grade reading level on most measures. Preoperative instructions showed less improvement by a chatbot. Inconsistencies occurred at rates of 1.1 and 0.6 per document for human authors and a chatbot, respectively. At least 1 inconsistency was found in 20 of 43 human-simplified (47%) and 11 of 43 chatbot-simplified (26%) instructions, with the higher rate of inconsistencies from humans associated with nonclinically significant omissions. Similar rates of critical inconsistencies were observed between human authors and a chatbot.Publisher's note: AI was effective in this study. If AI can simpligy surgical instructions, how would it do with hospice admission and other instructions?

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Understanding trauma in the context of direct care work in nursing homes

09/06/25 at 03:35 AM

Understanding trauma in the context of direct care work in nursing homesJournal of Applied Gerontology; by Alfred Boakye, Jennifer Craft Morgan, Candace L. Kemp, Antonius D. Skipper; 8/25Direct care workers (DCWs) experience job quality challenges such as heavy workload, low pay, and few benefits. Layered risks such as the COVID-19 pandemic and systemic racism have impacted DCWs, made them more vulnerable, and increased turnover and the precarity of the long-term care system and residents’ care. Findings suggest that DCWs are often crippled with challenges stemming from the impact of COVID-19, work-related factors, and personal factors. Understanding the intersection of trauma provides a detailed contextual description of care work, which is important for developing practical coping strategies, either at the personal or organizational levels, and developing more refined trauma-informed initiatives to build resilience and support DCWs.

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Acceptability and barriers to chronic pain treatment in refugee torture survivors

09/06/25 at 03:30 AM

Acceptability and barriers to chronic pain treatment in refugee torture survivorsJAMA Network; by Sargun Kaur Virk, Samantha Tham, Claudia Hatef, Tanzilya Oren, Lola Berger, Adam Tucker, Andrew Robert Milewski, Inmaculada de Melo-Martin, Gunisha Kaur; 8/25Which chronic somatic pain treatment modalities are acceptable to refugee torture survivors, and what factors influence their access to these treatments? Findings suggest that although refugee torture survivors are willing to engage in chronic pain treatment, structural and systemic barriers limit their ability to do so.Publisher's note: How are hospice care plans individualized to reflect unique needs of torture survivors?

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A digital therapeutic intervention for inpatients with elevated suicide risk: A randomized clinical trial

09/06/25 at 03:25 AM

A digital therapeutic intervention for inpatients with elevated suicide risk: A randomized clinical trialJAMA Network; by Craig J. Bryan, Patricia Simon, Samuel T. Wilkinson, Michael H. Allen, Jeremiah Perez, Caleb Adler, Khatiya Moon, Lauren Astorino, Kristen M. Carpenter, Luke Misquitta, Katherine Brownlowe, Lauren R. Khazem, Jarrod Hay, Austin G. Starkey, Julia Tartaglia, Helena Winston, Scott Simpson, Alecia D. Dager, Seth Feuerstein; 8/25Does a smartphone-based digital therapeutic intervention designed to deliver suicide-focused cognitive behavior therapy (CBT) reduce future suicide attempts among patients hospitalized with acutely elevated suicide risk? In this randomized clinical trial of 339 inpatients in psychiatric hospitals, no difference was found in time to first actual suicide attempt between those who used the digital therapeutic intervention and those who used the control application. The digital therapeutic intervention did not impact time to first suicide attempt after discharge among patients admitted for suicidal ideation and/or suicide attempts.Publisher's note: As AI is studied in healthcare, it's interesting to explore both what works and what doesn't.

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Sexuality and intimacy in the context of palliative and end-of-life care: A scoping review

09/06/25 at 03:20 AM

Sexuality and intimacy in the context of palliative and end-of-life care: A scoping reviewInternational Journal of Palliative Nursing; by Michelle Traverse, Susan D Mueller, Susan DeSanto-Madeya, Melissa A Sutherland; 8/25This scoping review identifies what is known about patient/partner sexuality and intimacy needs during end-of-life care and how healthcare professionals' (HCPs) approach these needs. A total of 18 articles were included in the review. Four themes were identified: 1) negative impact of serious illness on sexuality and intimacy, 2) barriers and facilitators to addressing sexuality, 3) tension between expansive and genital-focused approaches to sexuality and intimacy, and 4) a disconnect between patient/partner needs and HCP preparation. HCPs require clear and comprehensive training to improve their ability to address sexuality and intimacy during end-of-life care. Taking an expansive view of sexuality and intimacy during this time may facilitate HCP interventions.

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Risky prescribing and the epidemic of deaths from falls

09/06/25 at 03:15 AM

Risky prescribing and the epidemic of deaths from fallsJAMA Health Forum; Thomas A. Farley; 8/25In 2023, more than 41,000 individuals older than 65 years died from falls. More importantly, the mortality rate for falls among older adults in the US has more than tripled during the past 30 years. Drugs that cause drowsiness or impaired balance or coordination have been called fall risk–increasing drugs (FRIDs). The list of FRIDs is long and includes drugs such as β-blockers and anticholinergics, as well as proton pump inhibitors that may increase the risk of an injury during a fall. Four categories (opioids, benzodiazepines, gabapentinoids, and antidepressants) of central nervous system–active FRIDs are particularly concerning because of a combination of surging use and a strong association with falls. 

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Reconsidering neuraxial analgesia at end of life: Clinical, ethical, and socioeconomic perspectives

09/06/25 at 03:10 AM

Reconsidering neuraxial analgesia at end of life: Clinical, ethical, and socioeconomic perspectivesInterventional Pain Medicine; Sanjeet Narang , Jason Yong , David Hao, 9/25Pain is one of the most prevalent and distressing symptoms experienced by patients nearing end of life, particularly among those with cancer. While systemic opioids are the mainstay of treatment, their limitations necessitate consideration of alternative strategies. Neuraxial analgesia, including epidural and intrathecal drug delivery systems, offers targeted pain relief with reduced systemic burden. Yet despite supportive data, these interventions remain underutilized due to clinical, ethical, logistical, and socioeconomic barriers. This article examines the complex decision-making involved in offering neuraxial analgesia at the end of life, weighing risks and benefits, shifting patient goals, and the challenges of care coordination.

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Top ten tips palliative care clinicians should know about intensive care unit consultation

09/06/25 at 03:05 AM

Top ten tips palliative care clinicians should know about intensive care unit consultationJournal of Palliative Medicine; by Ankita Mehta, Karen Bullock, Jillian L. Gustin, Rachel A. Hadler, Judith E. Nelson, William E. Rosa, Jennifer B. Seaman, Shelley E. Varner-Perez, Douglas B. White; 8/25Critical illness and ICU stays can be extremely distressing for patients and their loved ones. Providing palliative care in the ICU, although a standard component of comprehensive care delivery, involves understanding the individual culture of each specific ICU, collaboration with multiple providers, and interfacing with surrogate decision makers while patients may not be able to communicate and are undergoing interventions that are unfamiliar to them and loved ones. These top ten tips aim to support palliative care clinicians providing consultation in ICUs. Specifically, these tips address initial relationship building with ICU clinicians and teams to foster effective collaboration, establishing goals of care by assessing health-related values, explaining treatment options, individualizing prognostic discussions, and managing end-of-life symptoms for patients while in the ICU and throughout ICU discharge transition.

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Palliative care use and end-of-life care quality in HR+/HER2- metastatic breast cancer

09/06/25 at 03:00 AM

Palliative care use and end-of-life care quality in HR+/HER2- metastatic breast cancerBreast Cancer Research and Treatment; by Julia G Cohn, Susan C Locke, Kris W Herring, Susan F Dent, Thomas W LeBlanc; 8/25Metastatic breast cancer (MBC) is incurable, despite therapeutic advances, especially in hormone receptor positive (HR+) and human epidermal growth factor-2 negative (HER2-) disease. Of 102 patients, 85 died during the study period, and over half (55%) received aggressive EoL [end of life] care. Half had some form of SPC [specialist palliative care], and rates of aggressive EoL care were comparable between those who engaged with SPC and those who did not. The most common indicators of aggressive EoL care included multiple ED visits (28%) and hospital admissions (23%) in the last 30 days of life as well as in-hospital location of death (24%). Although 72% enrolled in hospice care, 9% of patients were on hospice for ≤ 3 days. This real-world study demonstrates that many patients with HR + /HER2- MBC [metastatic breast cancer] receive aggressive EoL care despite some engaging with SPC and many enrolling in hospice. 

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[Japan] Clinical and communication factors associated with family conflict in palliative care units: A survey of bereaved families in Japan

09/06/25 at 03:00 AM

[Japan] Clinical and communication factors associated with family conflict in palliative care units: A survey of bereaved families in JapanCancer Medicine; by Jun Hamano, Kento Masukawa, Masanori Mori, Takashi Yamaguchi, Hiroyuki Otani, Hiroto Ishiki, Yutaka Hatano, Isseki Maeda, Satoru Tsuneto, Yasuo Shima, Tatsuya Morita, Yoshiyuki Kizawa, Mitsunori Miyashita; 9/25Family conflict is a common problem in palliative care and has been identified as a potential barrier to providing appropriate care... Our findings suggest that abrupt clinical deterioration is associated with family conflict. Confirming patients' and families' wishes regarding CPR during hospitalization may help reduce family conflict in PCUs.

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What do physicians want at the end? An international qualitative study on physicians’ personal end-of-life preferences and what influences them

09/03/25 at 03:00 AM

What do physicians want at the end? An international qualitative study on physicians’ personal end-of-life preferences and what influences them Palliative Care and Social Practice; by Sarah Mroz, Frederick Daenen, Sigrid Dierickx, Freddy Mortier, Ludovica De Panfilis, Luca Ghirotto, Toby Campbell, Kenneth Chambaere, and Luc Deliens; 7/4/25 Research Results: ... Most physicians prefer to avoid aggressive and life-prolonging treatment, physical and mental suffering, and being a burden. They prioritize being in a peaceful environment and communication with loved ones. Various factors influence preferences including cultural, social, and religious beliefs, and legislative environment, but most significant are the deaths of loved ones and clinical practice. Death and dying become normalized the more they are reflected upon and discussed, and this process can also provide personal growth which helps physicians provide better care to patients and families.

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Serious illness and end of life in LGBTQIA+ older adults

08/30/25 at 03:30 AM

Serious illness and end of life in LGBTQIA+ older adultsDelaware Journal of Public Health; by Sarah Matthews; 7/25Gender-affirming care is just as important during serious illness and end of life. Typically, gender-affirming hormone therapy is maintained throughout life to provide masculinizing or feminizing effects as desired. At end-of-life, it may be the person’s wish to continue hormones even if the medication poses additional risk. Whenever possible, gender expression preferences of LGBTQIA+ elders should be honored. TRANSforming Choices Healthcare Decisions Starter Guide is an excellent resource for transgender, gender-diverse, and gender-expansive people to make choices about their healthcare including gender-affirming care. Funeral directives are available to ensure that LGBTQIA+ elders’ funeral wishes are followed, including name, pronouns, and presentation of the body.

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Advance care planning in Hispanic populations with Parkinson’s Disease: Investigating disparities in end-of life care

08/30/25 at 03:25 AM

Advance care planning in Hispanic populations with Parkinson’s Disease: Investigating disparities in end-of life careClinical Parkinsonism & Related Disorders; by Taylor Peabody, Monica Abou-Ezzi, Lucila Hernandez, Henry Moore, Silvia Vargas-Parra, Alberto Cruz, Danielle S. Shpiner; 8/25ACP [advance care planning] is a topic of increasingly recognized importance among the PD [Parkinson's disease] research and patient communities. Despite evidence that many people with PD across ethnic groups consider this topic important, our study showed that Hispanic people with PD may have less access and experience with this aspect of care. These findings represent an important area for future study, so that all people with PD can benefit from the opportunity to participate in ACP if in alignment with their goals of care.

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Physician billing for advance care planning among Medicare fee-for-service beneficiaries, 2016-2021

08/30/25 at 03:20 AM

Physician billing for advance care planning among Medicare fee-for-service beneficiaries, 2016-2021The Permanente Journal; by Nan Wang, Changchuan Jiang, Elizabeth Paulk, Tianci Wang, Xin Hu; 8/25In 2016, the Centers for Medicare & Medicaid Services started reimbursing practitioners for their time spent providing advance care planning (ACP) with patients. Results: The percentage of practitioners billing ACP visits tripled from 1.76% in 2016 to 4.56% in 2021, with the highest percentage among hospice and palliative medicine practitioners (36.94%) in 2021. ACP service volume was similar by metropolitan status for hospice and palliative medicine, but it was higher in nonmetropolitan regions for cancer-related specialties, non-cancer terminal disease specialties, and primary and geriatrics care. This nationwide analysis showed low adoption of ACP billing by 2021, and it varied widely across specialties. This may reflect practical challenges of ACP related to comfort level with ACP discussion and documentation burden among the professional communities.

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Palliative care needs of older adults with and without dementia during post-acute care in skilled nursing facilities

08/30/25 at 03:15 AM

Palliative care needs of older adults with and without dementia during post-acute care in skilled nursing facilitiesJournal of Applied Gerontology; by Joan G Carpenter, Elisha Oduro, Nancy Hodgson, Shijun Zhu, Merve Gurlu, Mary Ersek, Laura C Hanson; 8/25Seriously ill older adults, including those living with Alzheimer’s disease and related dementias (ADRD), often receive disease-focused rehabilitative care in skilled nursing facilities (SNF) with little consideration for their palliative care (PC) needs. Using baseline data from a pilot pragmatic clinical trial (N=52), we conducted a cross-sectional study to compare the clinical characteristics and the PC needs of older adults with and without ADRD receiving SNF care. Functional decline was the most common global indicator for palliative care among both groups. While there was no statistically significant difference in PC needs between the two groups, the most prevalent PC needs for all were pain (63.5%), feeling anxious or worried (59.6%), family and friends being anxious or worried (57.7%), and need for information (46.2%). Older adults with and without an ADRD diagnosis who are admitted to post-acute SNF care may benefit from universal screening and tailored PC services.

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AI in palliative care: A scoping review of foundational gaps and future directions for responsible innovation

08/30/25 at 03:10 AM

AI in palliative care: A scoping review of foundational gaps and future directions for responsible innovationJournal of Pain and Symptom Management; by Selen Bozkurt, Soraya Fereydooni, Irem Kar, Catherine Diop Chalmers, Sharon L Leslie, Ravi Pathak, Anne M Walling, Charlotta Lindvall, Karl Lorenz, Ravi Parikh, Tammie Quest, Karleen Giannitrapani, Dio Kavalieratos; 8/25AI holds increasing promise for enhancing palliative care through applications in prognostication, symptom management, and decision support. However, the utilization of real-world data, the rigor of validation, and the transparency and reproducibility of these AI tools remain largely unexamined, posing critical considerations for their safe and ethical integration in sensitive end-of-life settings... AI in palliative care remains in early development, showing promise in areas such as prognosis and documentation support. However, limited validation, insufficient cross-site testing, and lack of transparency currently limit clinical applicability. Future research should emphasize external validation, inclusion of broader patient data, and adoption of open science practices to ensure these tools are reliable, safe, and trustworthy.

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Top ten tips palliative care clinicians should know about the future of generative intelligence

08/30/25 at 03:05 AM

Top ten tips palliative care clinicians should know about the future of generative intelligenceJournal of Palliative Medicine; by Pragat Patel, Raj Patel, Gilad Kuperman, Monica Consolandi, David Collett, Shunichi Nakagawa, Nicolas Burry, Karl B Bezak, Jake Strand, Mihir Kamdar, Judith E Nelson, William E Rosa, Craig D Blinderman; 8/25Artificial intelligence (AI) is transforming health care and has implications for palliative care (PC) and serious illness communication (SIC). This article integrates interdisciplinary and interprofessional expertise, providing key tips for PC clinicians to best leverage AI-driven tools to enhance PC practices, care efficiency, and patient- and family-centered outcomes. AI-driven tools range from predictive analytics to improve intervention delivery to AI-assisted communication and documentation of goals of care. Beyond these potential benefits are important ethical, logistical, and equity considerations that must be carefully addressed.

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[Canada] Simplifying palliative symptom management: Elastomeric infusions in hospice and home care

08/30/25 at 03:05 AM

[Canada] Simplifying palliative symptom management: Elastomeric infusions in hospice and home careBritish Journal of Nursing; by Vincetic Bozidar, Natalie Wm Hertzman, Daphne Broadhurst; 7/25Palliative care patients often require frequent, resource-intensive, intermittent subcutaneous injections or complex infusion pumps for end-of-life symptom management. Our findings suggest that continuous subcutaneous infusions via elastomeric infusion pumps offer a promising and feasible approach to end-of-life symptom management in hospice and home care. Elastomeric infusions may enhance simplicity, acceptability, safety, efficacy, and efficiency of care, compared to traditional routine subcutaneous injections.

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Ethical obligations to inform patients about use of AI tools

08/23/25 at 03:40 AM

Ethical obligations to inform patients about use of AI toolsJAMA; by Michelle M. Mello, Danton Char, Sonnet H. Xu2; 7/25When a health care organization decides to deploy an AI tool, it should decide whether notification or consent is ethically required. To decide that disclosure is not required at the point of care is not to conclude that organizations have no transparency obligations concerning their use of AI. Two complementary steps can help discharge these obligations. First, health care organizations’ websites and written materials distributed to patients should explain how the organization uses AI to deliver better, safer, more efficient care and protect staff well-being. This kind of transparency honors patients’ desire to know how their care may be affected by AI and may help some make decisions about where to seek care. 

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Exploring virtual reality as an intervention to improve symptom severity in hospice-eligible patients

08/23/25 at 03:35 AM

Exploring virtual reality as an intervention to improve symptom severity in hospice-eligible patientsAmerican Journal of Hospice and Palliative Care; by Hannah Maciejewski, Kathryn Levy, Catherine M Mann, Suzanne S Sullivan, Gina Schuster, Christopher W Kerr; 7/25Virtual reality (VR) as an intervention has appeared in the literature and in clinical settings across many different populations. To expand the use of this care option, it is worth considering the ways in which a VR application may benefit individuals with life-limiting illness in hospice and palliative care settings. The incorporation of VR as a therapy option may aid in symptom management and support people nearing the end of life in focusing on aspects of their overall well-being.

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Improved outcomes and cost with palliative care in the Emergency Department: Case-control study

08/23/25 at 03:30 AM

Improved outcomes and cost with palliative care in the Emergency Department: Case-control studyThe Western Journal of Emergency Medicine; Brandon Chalfin, Spencer M Salazar, Regina Laico, Susan Hughes, Patrick J Macmillan; 7/25This small pilot case-control study included a subset of all patients referred by emergency physicians and hospitalists for palliative care within 24 hours of registration, physically present in the ED. CONCLUSION: Embedding hybrid physicians in the ED significantly shortened hospital stays and reduced charges for seriously ill patients. A notable secondary outcome was that 26.5% of ED visits in the case group did not result in hospital admission, compared to all controls being admitted ... In addition, more cases than controls had a code status of comfort care at discharge ... These findings support the further exploration of integrating such physicians into ED settings to enhance patient care and optimize hospital resources.

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Trends in hospice and palliative care consults initiated in the emergency department: An eight-year utilization analysis

08/23/25 at 03:25 AM

Trends in hospice and palliative care consults initiated in the emergency department: An eight-year utilization analysisThe American Journal of Emergency Medicine; by Satheesh Gunaga, Abe Al-Hage, Alyssa Buchheister, Harish Neelam, Jessica Corcoran, Michael Welchans, Kirby Swan, Mahmoud Awada, Joseph Miller, Fabrice Mowbray; 8/25Emergency departments (EDs) play a central role in end-of-life care, yet the early integration of hospice and palliative care (HPC) is often underutilized. A total of 8,055 HPC consults were ordered for 6,370 unique patients. The average age was 78.1 years, with 56.4 % female and 75.0 % White. Of the cohort, 91.7 % were admitted, 5.3 % discharged home, and 53.2 % died in-hospital. HPC consults increased from 369 in 2016 to 1,355 in 2023 (367 % increase ... ). The ratio of hospice to palliative care consults reversed from 1.5:1 in 2016 to 1:1.9 in 2023.

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