Literature Review

All posts tagged with “Research News | Journal Article.”



Emotional and ethical impacts on healthcare professionals performing cardiopulmonary resuscitation

07/18/26 at 03:40 AM

Emotional and ethical impacts on healthcare professionals performing cardiopulmonary resuscitationAmerican Journal of Hospice & Palliative Medicine; by Patrick J. Macmillan, Susan Hughes, Dumindra Gurusinghe, Allison Go, Chase Lancaster, Iris Price; 6/26Many studies exist outlining poor outcomes related to cardiopulmonary resuscitation (CPR) administered to patients who are elderly and/or have comorbid medical conditions with sudden cardiac arrest. Studies show only 10% of patients with out-of-hospital cardiac arrest and initial asystole survive until they reach the hospital. Less than 5% survive until hospital discharge with good neurologic function. This study presents data that suggests that there is an association between moral distress and performing CPR on individuals who are elderly with multiple comorbid medical conditions. More than sixty percent of our respondents were challenged emotionally during these types of code situations, and a similar number of healthcare workers felt the code could be considered unethical.

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Restarting medications after deprescribing in adults discharged from hospital to skilled nursing

07/18/26 at 03:35 AM

Restarting medications after deprescribing in adults discharged from hospital to skilled nursingJAMA Network Open; by Thomas J. Reese, Sandra F. Simmons, Eduard E. Vasilevskis, Emily K. Hollingsworth, Matthew S. Shotwell, Amanda S. Mixon; 6/26Question: Among older adults discharged to skilled nursing facilities (SNFs) after hospital-initiated deprescribing, what is the frequency and timing of medication restarts ...?  In this cohort study analyzing data from 2 randomized trials with a total of 598 participants, 15.9% of deprescribed medications were restarted. Higher health literacy and longer intervention exposure were associated with fewer restarts, whereas more prescribers, higher number of baseline medications, and fewer pharmacies were associated with medication restarts; restart during the SNF stay was associated with greater 90-day hospital readmissions. Conclusions: In this cohort study, approximately 1 in 6 deprescribed medications were restarted within 90 days, with nearly half occurring soon after SNF discharge. Patient factors and markers of care fragmentation were associated with restart, suggesting that enhancing transitional care and postdischarge support may improve the durability of hospital-initiated deprescribing.

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Toward home cancer care—Reducing time toxicity for the right patients with prostate cancer

07/18/26 at 03:30 AM

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Breast-directed palliative radiotherapy in metastatic and inoperable locally advanced breast cancer: From clinical efficacy to psychosocial impact

07/18/26 at 03:25 AM

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Reach of palliative care in Parkinson disease-Progress and gaps after a national team-based implementation project

07/18/26 at 03:20 AM

Reach of palliative care in Parkinson disease-Progress and gaps after a national team-based implementation projectNeurology in Clinical Practice; by Sandhya Seshadri, Umer Akbar, Peggy Auinger, Nicole Andrea Lessard, Megan Dini, Sally A. Norton, Hillary D. Lum, Jodi Summers Holtrop, Janis M. Miyasaki, Christina L. Vaughan, Benzi M. Kluger; 6/26While clinical trials demonstrate PC [palliative care] improves quality of life for PWP  [people with Parkinson disease] and carepartners, little is known about the impact of PC on their experiences of receiving care in real-world settings. At COEs [Parkinson's Foundation US-based Centers of Excellence], [surveyed] PWP reported significant increases in non-motor symptom (NMS) assessment ... and pain management ...  Emotional and spiritual needs were addressed more frequently ... Advance care planning (ACP) discussions [and documentation] rose ... Communication ratings and knowledge of PC were high (>85%) and stable across surveys.

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"Reconciling"- conceptualising the grieving process of family members involved in assisted dying: A grounded formal theory

07/18/26 at 03:15 AM

"Reconciling"- conceptualising the grieving process of family members involved in assisted dying: A grounded formal theoryBMC Palliative Care; by Jonathan Bayuo, Prince Kyei Baffour, Elisha Baafi Oduro, Deborah Adedibu; 6/26While theoretical frameworks for understanding the grieving process are well-established, the advent of assisted dying presents a novel and under-examined context for grief and bereavement. Thus, this study sought to generate a theory explaining the grieving process of family members involved in assisted dying. Reconciling, as a mid-range theory, extends existing grief models by demonstrating that bereavement in assisted dying involves a proactive, ethically charged negotiation of autonomy, suffering, and relational responsibility; dimensions not accounted for in stage-based or oscillation models. The grieving process in assisted dying is best understood as Reconciling, a dynamic, iterative negotiation of autonomy, suffering, love, and loss. Families move through ambivalence, anticipation, transition, and aftermath in ways that blend emotional complexity with profound meaning-making.

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National Health Expenditure Projections, 2025–34: Strong utilization growth initially, legislative impacts later

07/18/26 at 03:10 AM

National Health Expenditure Projections, 2025–34: Strong utilization growth initially, legislative impacts laterHealth Affairs; by Jacqueline A. Fiore, Andrea M. Sisko, John A. Poisal, Sheila D. Smith, Gigi A. Cuckler, Andrew J. Madison, Sean P. Keehan, Kathryn E. Rennie, and Nicholas J. Feehley; 6/26By 2034, national health spending is projected to total nearly $9.0 trillion and to represent 20.6 percent of the economy, compared with $5.3 trillion and 18.0 percent in 2024. The rate of national health spending growth during this period is influenced by continued elevated use of medical services and goods through 2026; major legislative changes that affect insurance coverage and spending through 2028; and continued demographic shifts toward public programs, mainly Medicare. The insured share of the population is expected to be 90.5 percent in 2034, compared with 91.8 percent in 2024.

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[Spain] Post-recurrence management of malignant glial brain tumors: Therapeutic strategies, evidence and limitations, palliative care, terminal sedation, and end-of-life considerations

07/18/26 at 03:05 AM

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Serious illness and health care threats to personal legacy goals

07/18/26 at 03:05 AM

Serious illness and health care threats to personal legacy goalsThe Permanente Journal; by Marlaine Figueroa Gray, Matthew P Banegas, Nora B Henrikson; 6/26High-quality care for people with serious illness requires understanding what matters most. Although goals-of-care conversations may emphasize values and treatment preferences, patients hold goals related to identity, relationships, and legacy; how they wish to be remembered and what they hope to leave behind. Five themes emerged [from the participant interviews]: 1) participants actively planned for legacy, with legacy goals often clarified by serious illness; 2) illness and its care introduced threats to legacy goals; 3) financial strain and insurance coverage were major threats; 4) participants believed their care would differ if teams understood their legacy goals; and 5) participants wanted to communicate their legacy goals to their care teams. Integrating legacy-related conversations into palliative care may enhance person-centered care by addressing identity, relationships, and meaning alongside medical preferences.Assistant Editor's note: This article summary describes a very important aspect of end-of-life planning. Exploring with patients their legacy goals is as important as discussing their preferences surrounding their care. Including legacy goals as an integral component of goals of care and advance care planning discussions would yield a greater understanding of what kind of care would most honor the patient.

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[Iran] Prerequisites and challenges of the role played by death doula for supporting patients with cancer in end-of-life (EOL) stages: Qualitative study

07/18/26 at 03:00 AM

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Contextualizing the dead donor rule in an era of voluntary euthanasia

07/18/26 at 03:00 AM

Contextualizing the dead donor rule in an era of voluntary euthanasiaNew England Journal of Medicine; by Carter Winberg, Ian Ball, Robert D. Truog; 7/26Growing acceptance of voluntary euthanasia, which opens the door to death by organ donation, warrants a recontextualization of the dead donor rule and assessment of the ethical principles involved.Publisher's note: This article was discussed by NPR (A new proposal for organ donation sparks concern; NPR; by Rob Stein; 7/26). Should surgeons be allowed to perform euthanasia by removing patients' hearts and other organs while they're still alive? Doctors try a controversial technique to reduce the transplant organ shortage The idea, dubbed "Death by Organ Donation," would enable euthanasia patients to donate organs for transplantation in a way that would make their organs more likely to be usable. It would also kill them. There are interesting ethical points on both sides of the discussion.

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When technology meets its limits: Integrating Medical Aid in Dying with withdrawal of a left ventricular assist device

07/18/26 at 03:00 AM

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Evaluation of a pharmacist-driven discharge medication reconciliation service

07/16/26 at 03:00 AM

Evaluation of a pharmacist-driven discharge medication reconciliation service Pharmacy Times; by Missy Montino, PharmD, Madison Holmes, PharmD, BCPS, Shannon Pierce, PharmD, CPh, BCPS, Randi Silcox, PharmD, Anna-Marie Freeland, PharmD, Bola Habeb, MD; 7/13/26 Introduction: Medication reconciliation is a systematic process utilized to ensure the accuracy and consistency of a patient’s medication information across transitions in care. It involves comparing the patient’s current medication regimen with the prescribed medications to identify and resolve discrepancies, such as omissions, duplications, dosing errors, or potential drug interactions. ... Discussion and Conclusion: ... This study adds to the body of evidence supporting pharmacy’s positive impact on patient health outcomes, specifically in reducing 30-day readmission rates and identifying clinical interventions. This reinforces the benefit of a pharmacist-driven discharge medication reconciliation service. ...

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[United Kingdom] Development of the ‘Culturally Informed Ecological Model of Grief’ – a national qualitative study of bereavement experiences among ethnically diverse communities

07/15/26 at 03:00 AM

[United Kingdom] Development of the ‘Culturally Informed Ecological Model of Grief’ – a national qualitative study of bereavement experiences among ethnically diverse communities BMC Medicine; by Catriona R Mayland, Emily Fisher, Adejoke O Oluyase, Nikel-Shaniece Hector-Jack, Toslima Khatun, Rukia Saleem, Naureen Khan, Shirin Shahid, Riffat Mahmood, Gurpreet Grewal-Santini, Monika Afolabi, Candice Wang, Sarah Ng, Rashmi Kumar, Katherine Bristowe, Emily Harrop, Zoebia Islam, Jonathan Koffman, Gurch Randhawa, Lucy E Selman & Sabrina Bajwah; 7/14/26  Background: Among people from ethnically diverse communities, evidence regarding bereavement experiences and support needs is limited; there are known inequities in access to formal bereavement support. Conclusions: Racism was evident across multiple settings and closely intertwined with bereavement, compounding the emotional burden of grief. This study represents the largest qualitative investigation of bereavement among ethnically diverse communities in UK healthcare to date, providing a robust evidence base for improving equity in support. Bereavement services must prioritise cultural safety and actively address structural racism. The ‘Culturally Informed Ecological Model of Grief’ offers a new framework guiding more equitable bereavement support, relevant across national and international contexts.

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Utilization of hospice and palliative care among patients with mental illness: a retrospective cohort study

07/14/26 at 03:00 AM

Utilization of hospice and palliative care among patients with mental illness: a retrospective cohort study Journal of the American Geriatrics Society; by Sean O'Mahony, Utpol Das, Yuanyi Zhang, Anirudh S. Babu, Mukaila A. Raji, James Gerhart, Yong-Fang Kuo; 7/11/26 Background: Individuals with mental illness (MI) experience premature mortality and health disparities, yet little is known about their access to hospice and palliative care. Conclusions: Mental illnesses were associated with complex hospice utilization patterns characterized by longer length-of-stay, higher likelihood of enrollment far from death, lower likelihood of enrollment within 180 days before death, and lower palliative care consultation use in some groups.

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Implementation of a serious illness conversation program in a health system: A retrospective observational study

07/11/26 at 03:40 AM

Implementation of a serious illness conversation program in a health system: A retrospective observational studyJournal of Palliative Medicine; by Glen Varns, Abbey Sidebottom, Katy Hentges, Sandra Castro-Pearson, Jan Richardson, Emily Downing; 6/26Serious illness conversation (SIC) is a structured conversation framework designed to improve shared decision making and promote goal-concordant care with patients anticipating end-of-life care decisions. Objective: Examine reach, timeliness, and quality of SIC implementation across a health system after implementation of a SIC Program (SICP) [and] examine factors associated with SIC completion for eligible patients. Factors associated with SIC included palliative care visits ... , a primary care provider in the system ... , and an inpatient admission with discharge to home care ... Patients with dementia ... were less likely to have SIC. Conclusion: Systemwide implementation of an SICP engaged [only] half of eligible patients; many of those had multiple documented conversations prior to death.

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The doctor will see you now--or will they? Theorizing AI’s impact on Black patients and providers in health care

07/11/26 at 03:35 AM

The doctor will see you now--or will they? Theorizing AI’s impact on Black patients and providers in health careSocial Currents; by Adia Harvey Wingfield, Tyrell Spencer; 6/26As far as recent innovation practices go, artificial intelligence (AI) represents one of the major disruptions reshaping various aspects of human life. Health care is perhaps one of the industries where AI stands to be most transformative, particularly as it is increasingly used to diagnose illnesses, assist in creating treatment plans, reduce human error, and offer routine patient services. Yet despite its rapid growth, AI technology still reflects human biases and perceptions, allowing it to replicate existing inequalities. These inequalities could take on particular significance given persistent occupational stratification and increasing racial diversity. In this paper, we theorize how the growing reliance on AI in the US health care system will affect Black care providers and patients.

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Impact of specialized pediatric palliative care on bereaved parents' mental and physical health

07/11/26 at 03:30 AM

Impact of specialized pediatric palliative care on bereaved parents' mental and physical healthJournal of Pain & Symptom Management; by Claudia Delgado-Corcoran, Huong D. Meeks, Sarah E. Wawrzynski, Barry P. Markovitz, Brandy Harman, Jasmine R. Masih, Kuan Li, Mark Harousseau, Dominic Moore, Jacob Wilkes, Stefanie G. Ames; 6/26Pediatric death can lead to long-term adverse effects on parents’ health. [In this study] of 776 deceased children linked to 773 mothers and 711 fathers, 36.1% received a SPPC [specialized pediatric palliative care] consultation prior to death. Higher rates of mental and physical health burden were observed in mothers than fathers across all time points. Lack of SPPC was associated with increased risks for new mental and physical health burden for mothers within 12 months after the child’s death ... Conclusions: Bereaved parents, especially mothers, experienced new mental and physical health burden up to 24 months after a child’s death.

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Early palliative care for people with primary malignant brain tumors: A systematic review

07/11/26 at 03:25 AM

Early palliative care for people with primary malignant brain tumors: A systematic reviewJournal of Palliative Medicine; by Jennifer C. Hall, Connor Barrett, Soren Christensen, Juliet Dalton, Samantha Kaplan, Christopher A. Jones, Margaret O. Johnson; 6/26In some populations with advanced cancers, early palliative care (ePC) has been shown to improve quality of life (QoL) and reduce aggressive interventions, but its role and timing in primary malignant brain tumors (PMBT) remains poorly defined. Definitions of ePC varied with “early” defined relative to diagnosis, treatment milestones, or death. Across studies, a minority of patients received PC (15%–40%), with most referrals occurring late in the disease course. Earlier PC was associated with reduced aggressiveness of EoL care, decreased health care utilization, and, in some cases, longer survival. Evidence suggests ePC for PMBT is infrequently implemented yet feasible and may reduce aggressive EoL care and improve outcomes. 

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Palliative care for older adults with hip fracture: An explanatory sequential mixed-methods study

07/11/26 at 03:20 AM

Palliative care for older adults with hip fracture: An explanatory sequential mixed-methods studyJournal of Pain & Symptom Management; by Daniel I Hoffman, Sydney Moore, Amanda J Reich, Christina Sheu, Mengyuan Ruan, Masami Tabata-Kelly, Kate Sciacca, Tamryn F Gray, Daniel Dohan, Charlotta Lindvall, Zara Cooper; 6/26After hip fracture, older adults experience burdensome treatments and high mortality; they may therefore benefit from palliative care (PC). Among 1,433 hip fracture admissions, GOCC [goals of care conversations], hospice discussions, and specialty PC were documented in view on their role in GOCC. Conclusion: Limited standardization, role uncertainty, and cultural factors limited PC documentation and delivery, highlighting opportunities to strengthen PC integration in surgical care.

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Experiences of end-of-life care among incarcerated individuals: A qualitative interpretative meta-analysis

07/11/26 at 03:15 AM

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Outcomes for hospitalized patients with comfort measures only orders

07/11/26 at 03:10 AM

Outcomes for hospitalized patients with comfort measures only ordersJournal of Palliative Medicine; by Gina Piscitello, Donna Durant, Tami Minnier, Marika Haranis, Robert M Arnold, Jane Schell; 6/26Clinicians place comfort measures only (CMO) orders for hospitalized patients at the end-of-life when a decision has been made to focus on patient comfort and allow the natural dying process to occur. Our primary aim was to assess the associations of specialty palliative consults (SPC) or documented goals of care conversations (GOCC) with in-hospital mortality among patients with CMO orders. Of 6,789 hospitalized patients with CMO orders ... seventy-three percent died in-hospital, and 22% were discharged with hospice. SPC placed anytime during hospital admission were associated with lower in-hospital mortality ... and higher discharge with hospice ... In contrast, documented GOCC anytime during admission were associated with higher in-hospital mortality ...  and lower discharge with hospice ...

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[Hong Kong SAR] Digital self-management of symptoms and quality of life for patients with advanced cancer-A randomized clinical trial

07/11/26 at 03:05 AM

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Survival variation and predictors of length of stay in US hospice patients

07/11/26 at 03:05 AM

Survival variation and predictors of length of stay in US hospice patientsInternational Perspectives and Future Directions for Practice, Research, and Policy; by Ian Duncan, Xiyue Liao, Terri Maxwell; 6/26End-of-life (EOL) patients in the US Medicare program represent a large and growing population, as well as a disproportionate share of Medicare’s costs. Survival of patients in hospice is, however, highly variable, implying an opportunity for improved management by enhancing the prediction of survival. Actuaries, health economists, policy analysts, and health services researchers have studied expenditures at the EOL for Medicare decedents for many years, finding that survival at EOL is highly variable. We discuss the utilization of hospice benefits for patients at the EOL in the United States.

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An end-of-life care approach defining a new standard of care

07/11/26 at 03:00 AM

An end-of-life care approach defining a new standard of careJAMDA; by David N. Hoffman; 6/26The Institute for Healthcare Improvement (IHI) Leadership Alliance established an End-of-Life Care/Ending-Life Care Accelerator to define a continuum of care for patients as they progress from curative care, to palliative care, to hospice care, to final care planning, including ending life care interventions such as Medical Aid in Dying (MAiD), Voluntarily stopping eating and drinking (VSED), and palliative sedation. This accelerator defined as its goal the task of breaking down barriers between care providers which has been illuminated by research recently conducted by the Completed Life Initiative (CLI). CLI’s research efforts in this area started with an ongoing examination of nationwide hospice organization policies to provide referral for active intervention at the end of life. That effort was refocused on the widespread noncompliance of California and Washington state hospice organizations with a state law requirement to post on the organizations website a list of interventions made available by the hospice organization.

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