Current understanding of cardiovascular autonomic dysfunction in multiple sclerosis

Current understanding of cardiovascular autonomic dysfunction in multiple sclerosis
Heliyon; Insha Zahoor, Guodong Pan, Mirela Cerghet, Tamer Elbayoumi, Yang Mao-Draayer, Shailendra Giri, Suresh Selvaraj Palaniyandi; 8/24
Autoimmune diseases, including multiple sclerosis (MS), are proven to increase the likelihood of developing cardiovascular disease (CVD) due to a robust systemic immune response and inflammation. CVD in MS patients can affect an already damaged brain, thus worsening the disease course by causing brain atrophy and white matter disease. Treating vascular risk factors is recommended to improve the management of this disease. Additionally, clinicians should monitor for cardiovascular complications while prescribing medications to MS patients, as some MS drugs cause severe CVD.