Literature Review

All posts tagged with “Clinical News | Disease Specific.”



Nearly one in four US adults projected to develop heart failure

10/06/26 at 03:15 AM

Nearly one in four US adults projected to develop heart failureCardiologytoday; by Scott Buzby; 10/5/26One in four U.S. adults are projected to develop HF in their lifetime. The prevalence of HF is expected to increase from 3% currently to 3.8% by 2050. HF mortality represented 14.6% of all deaths in the U.S... Nearly one in four U.S. adults are projected to develop heart failure in their lifetime, and the overall prevalence of the disease is expected to keep rising due to an aging population with increasing comorbidities, researchers reported.

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Breast cancer awareness month

10/05/26 at 02:00 AM

Breast cancer awareness month BreastCancer.org; by Jennifer Carr; 9/21/26 October is about more than pink ribbons. ... Understanding the goals behind the global campaign and the emotions felt by the many different people living with the disease may help you decide if and how you want to commemorate the month. Breast Cancer Awareness Month is an international health campaign that’s held every October. The month aims to promote screening and reduce the risk of the disease, which affects 2.4 million women worldwide.1 Known best for its pink theme color, the month features a number of campaigns and programs designed to: ...

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Projected aging among people with HIV in the US

10/03/26 at 03:35 AM

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Respecting spinal cord injury patient autonomy in the context of terminal extubation

10/03/26 at 03:25 AM

Respecting spinal cord injury patient autonomy in the context of terminal extubationJournal of Palliative Care; by Rainy B S Wortelboer, Lauren Hall, Fareea Khaliq; 9/26Terminal extubation ... is a legally and ethically accepted practice in the United States where mechanical ventilation is withdrawn when ongoing life-sustaining treatment no longer aligns with a patient's stated goals of care. Nearly 42% of intensive care unit deaths involve withdrawal of such measures. Discussions regarding goals of care may be complicated by quality-of-life concerns and potential ableist bias when physical dependence is misinterpreted as incompatible with meaningful life. We present a case-based ethical analysis of an 88-year-old male with traumatic high-level cervical SCI [spinal cord injury] who requested terminal extubation following prolonged hospitalization. After interdisciplinary evaluation confirmed decision-making capacity and with strong family support, he elected hospice care. He was extubated with palliative support and passed 48 h later. This case highlights the intersection of autonomy, capacity, and ethics in end-of-life decisions for patients with SCI and underscores the importance of ethical, patient-centered approaches when considering withdrawal of life-sustaining treatment.

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Oral anticoagulants in patients with Atrial Fibrillation and advanced CKD not requiring dialysis

10/03/26 at 03:20 AM

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A pilot feasibility study of PAL-CHW-PDAC, a digitally enhanced community health worker-led intervention to facilitate stepped palliative care in patients with pancreatic cancer

10/03/26 at 03:15 AM

A pilot feasibility study of PAL-CHW-PDAC, a digitally enhanced community health worker-led intervention to facilitate stepped palliative care in patients with pancreatic cancerJournal of Palliative Medicine; by Nikhil R Thiruvengadam, Maud Celestin-Joachim, Lizbeth Rivas, Nishita Matangi, Arman Bahmani, Matthew Oroso, Joel Brothers, Kendrick Che, Andrew Chang, Emmanuel Eguia, Paul Leonor, Gina Mohr, Raja Narayan, Sagar Pathak, Susanne Montgomery, Betty Ferrell; 9/26Pancreatic Ductal Adenocarcinoma (PDAC) is associated with substantial morbidity and poor quality of life (QOL). Early palliative care (EPC) has been shown to improve QoL and reduce symptom burden in PDAC, but only a minority of PDAC patients receive it. Using three conceptual models, we developed a community health worker (CHW)-led intervention to help facilitate stepped PC. Ninety-four percent of patients strongly agreed that the intervention was acceptable. Themed common responses highlighted by patients centered around the critically important role of the CHW in their care, especially as symptoms worsened. Patients' physical QoL and symptom burden improved from baseline to 12 weeks, while 83% of patients completed their ACP [advance care planning].

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What hospitals need to change before data catches up

09/30/26 at 03:00 AM

What hospitals need to change before data catches up ICD10 monitor; by Penny Jefferson, MSN, RN, CCDS, CCDS-O, CCS, CDIP, CRC, CHDA, CRCR, CPHQ, ACPA-C; 9/29/26 Medicare Advantage has traditionally occupied a familiar space in hospital operations: prior authorization, utilization management, denials, risk adjustment, and reimbursement. With the FY 2027 Inpatient Prospective Payment System final rule, healthcare organizations need to add another significant area to that list—hospital mortality performance. The Centers for Medicare & Medicaid Services (CMS) finalized modifications to five existing 30-day, all-cause, risk-standardized mortality measures to include eligible Medicare Advantage beneficiaries ...: acute myocardial infarction (AMI), heart failure, pneumonia, chronic obstructive pulmonary disease (COPD), and coronary artery bypass graft (CABG) surgery.

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NIH grant advances research on palliative care at home

09/28/26 at 03:00 AM

NIH grant advances research on palliative care at home Indiana University School of Nursing; by Glenda Shaw; 9/23/26 ... A new research project led by Indiana University School of Nursing assistant professor Lyndsay DeGroot, PhD, RN, aims to bring palliative care directly to patients in their homes through a telephone-based program that could make supportive care more accessible for people living with serious chronic illness. To support this work, DeGroot has received a NIH-National Heart, Lung, and Blood Institute (NHLBI) five-year K23 Career Development Award totaling $916,000. The award will fund her project, “Implementing Community-Based Palliative Care for Adults with Heart Failure or Chronic Obstructive Pulmonary Disease.”

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Assessing palliative care screening tools for patients with cancer

09/28/26 at 03:00 AM

Assessing palliative care screening tools for patients with cancer Oncology Nurse; by Vicki Moore, PhD; 9/25/26 A total of 19 screening tools for assessing palliative care needs among patients with cancer were identified in a recent scoping review, but with variation in their applications. The findings of the review were reported in the journal BMJ Supportive & Palliative Care. ... The researchers identified 37 studies that reported a total of 19 screening tools for assessing palliative care needs of patients with cancer, which the researchers grouped into 3 categories. These included universal tools, tools with cancer-specific modules, and tools specifically developed for patients with cancer. 

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[Germany] Unmet needs of heart failure patients across the different domains of palliative care – A qualitative interview study

09/26/26 at 03:05 AM

[Germany] Unmet needs of heart failure patients across the different domains of palliative care – A qualitative interview studyHeart & Lung; by Chiara Pfeffer, Felix Schoenratha, Lennart Tügend, Anahita Khamseh, Susanne Jöbges, Johann Ahne, Asita Behzadie, Moritz Blum; 9/26Currently, palliative care provision for patients with heart failure (HF) is limited and usually not tailored to the specific needs they might have. In this study, we sought to gain a better understanding of the needs and expectations expressed by patients with HF regarding palliative care. Participants expressed needs and expectations across all eight domains of palliative care. Some needs were specific to HF, e.g. for more HF expertise among all healthcare providers. Other needs were more generally associated with serious illnesses, e.g. long term access to psychological counselling for patients and caregivers, help with coming to terms with limited life expectancy, or provision of information in accessible language. Patients with HF express a host of unmet needs, many of which could be addressed by palliative care.

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[France] Deactivation of cardiac devices at the end of life: Clinical and ethical challenges

09/26/26 at 03:00 AM

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Understanding low hospice utilization among ESRD patients

09/22/26 at 03:00 AM

Understanding low hospice utilization among ESRD patients0Hospice News; by Jim Parker; 9/21/260Hospice care is underutilized among end-stage renal disease (ESRD) patients, often due to systemic factors. More than 831,000 Americans are living with kidney failure, according to the National Institutes of Health. In 2023 alone, new cases totaled 131,564. Yet, end-stage renal disease patients in 2024 represented 1.3% of Medicare decedents who elected the Medicare Hospice Benefit, the National Alliance for Care at Home reported. This was 24,336 patients.0Concerns over access to dialysis is a major contributor to the low utilization, according to Compassus Chief Medical Officer Dr. Kurt Merkelz.03330The prospect of giving up dialysis deters many ESRD patients from entering hospice. Those that do may come to hospice very late because once they stop dialysis the patient will have approximately one week to live, Merkelz said.

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Missed opportunities for goals-of-care conversations in a patient with end-stage juvenile Huntington’s disease: A case report

09/19/26 at 03:25 AM

Missed opportunities for goals-of-care conversations in a patient with end-stage juvenile Huntington’s disease: A case reportAmerican Journal of Hospice & Palliative Medicine; by Ignacio Borque, Nuria Perez ´ de Lucas, Alicia Gonzalez, Eduardo Bruera; 8/26Juvenile Huntington’s disease (JHD) is a rare, severe neurodegenerative disorder with early onset, high symptom burden, and a predictable trajectory toward advanced disability and premature death. Despite this, goals-of-care (GOC) conversations and advance care planning are often delayed, leading to reactive, crisis-driven decisions and increased emotional burden for families and clinicians. We present a 30-year-old woman with genetically confirmed JHD, diagnosed at age 14, who declined progressively over more than 15 years. Despite longstanding neurological follow-up and repeated hospital admissions, palliative care referral occurred only 20 days before death. Late palliative care integration limited anticipatory planning and shifted complex decisions into a stage with little room for deliberation, when cognitive and clinical deterioration constrained meaningful participation.

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Palliative care and hospice utilization in patients with relapsed or refractory diffuse large B-cell lymphoma in the era of CART and novel immunotherapies

09/19/26 at 03:20 AM

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Top ten tips palliative care clinicians should know when caring for seriously ill patients with stimulant use disorders

09/19/26 at 03:15 AM

Top ten tips palliative care clinicians should know when caring for seriously ill patients with stimulant use disordersJournal of Palliative Medicine; by Rebekka DePew, Nicole Dussault, Kyle Quirk, Erin Vipler, Josh Borris, Sandra DiScala, Teddy Scheel, Katrina Nickels, Gregg Robbins-Welty, Janet Ho; 8/26Stimulant use disorder (StUD) is common in the hospice and palliative care (PC) setting, though guidance for clinicians remains limited. Stigma around stimulant use is widespread and can lead to impaired clinician/patient communication, poor symptom control, and lower quality of care. PC clinicians should be able to diagnose StUD, understand the potential pharmacologic and nonpharmacologic management options, engage with patients in a trauma-informed way, and refer to addiction medicine colleagues when appropriate. When utilizing opioids for pain management, PC clinicians should be aware of the impact of stimulant use on opioid risk and toxicity. In this article, a multidisciplinary group of PC, hospice, addiction medicine, psychiatry, ethics, and pharmacy clinicians presents ten practical tips for caring for seriously ill patients with current or prior StUD.

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Beyond the bottle: a whole person approach to pain management for veterans enrolled in inpatient hospice

09/10/26 at 02:00 AM

Beyond the bottle: a whole person approach to pain management for veterans enrolled in inpatient hospice Medscape; by Tracy Shamas, APRN, MSN, ACHPN, Andrea Ruskin, MD, HEC-C, and Alexandra Laffer, PhD; 9/9/26 Background: ... Veterans Affairs inpatient hospice units are uniquely positioned to implement non-pharmacological pain interventions due to longer lengths of stay and broader resources compared to Medicare GIP-regulated settings. This quality improvement project aims to support the uptake and utilization of non-pharmacological pain management interventions for veterans receiving inpatient hospice care. ... Conclusions: Initial findings show that veterans with pain at end-of-life express interest in holistic non-pharmacological options, and integrating these approaches is feasible within inpatient hospice care. ... 

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When lung cancer spreads to the liver: what to expect

09/09/26 at 03:00 AM

When lung cancer spreads to the liver: what to expect Everyday Health; by Ashley Welch, medically reviewed by Tingting Tan, MD, PhD; 9/8/26 Liver metastasis from lung cancer occurs when cancer cells from the tumor in the lung travel to the liver. Also known as stage 4, it’s the most advanced stage of lung cancer. ...

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Impact of outpatient palliative care consult triggers on end-of-life outcomes in a VA hematology/oncology clinic

09/09/26 at 03:00 AM

Impact of outpatient palliative care consult triggers on end-of-life outcomes in a VA hematology/oncology clinic Medscape; by Morgan Lyttle, MD, Michelle Popadiuk, MBA, LPN, RHIT, ODS-C, Seema Limaye, MD, Alexi Vahlkamp, Shannon Carrigan, MD, and Jean Vendiola, MD; 9/4/26 ... Conclusions: Outpatient palliative care (PC) triggers successfully shifted referral origin from inpatient to outpatient, halved the rate of trigger-eligible patients not receiving PC, and maintained hospice engagement despite loss of the inpatient oncology service. Future directions include expanding triggers to other subspecialty clinics managing oncology patients.

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Central Illinois nursing home fined $25K by state after resident's death

09/08/26 at 03:00 AM

Central Illinois nursing home fined $25K by state after resident's death Pekin Daily Times, Perioa, IL; by Zach Roth; 9/6/26 A Canton nursing home was fined $25,000 after a resident died last year after being taken off medication that was prescribed to prevent blood clots. ... On March 31, 2025, a verbal order was given to stop providing Xarelto because the woman began hospice care one month prior. ... The care plan noted that she had a history of strokes and that medication needed to be provided as ordered by her doctor. ... The hospice's owner said that the power of attorney had contacted them after the woman had died asking about the medication situation, noting that they hadn't seen anything to show that her Xarelto had been discontinued. The hospice owner also said that they hadn't received an order from a hospice physician or nurse to discontinue it. Editor's Note: Details are more complex than space allows in the short summary above. A verbal order to stop a medication, without a documented physician directive or clear communications with the family, is a quiet risk hiding in plain sight at hospice transitions — one that can hasten death rather than ease it. Deprescribing has its place in end-of-life care, but only through structured, physician-ordered, shared decision-making. Does your hospice's process protect against this, or could it happen to one of your patients tomorrow? 

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Inpatient palliative care utilization in gynecological malignancies: a national inpatient study

09/08/26 at 03:00 AM

Inpatient palliative care utilization in gynecological malignancies: a national inpatient study Medscape; by Lydia Francis, LF and Benjamin Easow, MD; 9/3/26 Conclusions: Only 1 in 6 hospitalizations for gynecological malignancies had documented palliative care, reflecting underutilization in a population with substantial supportive care needs. Palliative care concentration among older, higher-acuity admissions suggests late referral rather than early integration. These findings support timely palliative care expansion in gynecological malignancies to improve symptom management and goal-concordant care.

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Sorrow, unpermitted: A narrative review of grief in chronic liver disease

09/05/26 at 03:35 AM

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Perspectives on palliative care among patients with pancreatic cancer: A pilot study

09/05/26 at 03:10 AM

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Nearly half of veterans with stage IV cancer die without hospice: a national VHA analysis of 45,397 decedents

09/04/26 at 03:00 AM

Nearly half of veterans with stage IV cancer die without hospice: a national VHA analysis of 45,397 decedents Medscape; by Sasmith Menakuru, MD; Alexander Quattlebaum, MD; Chance Bloomer, MD; Lara Khoury, MD; Abdulsabur Sanni, MD; Michael Goodman, MD; 9/3/26  Results: Of 45,937 veterans, 20,338 ... had no hospice admission or consultation.  ... Conclusions: Hospice access for veterans with Stage IV cancer deteriorated during COVID-19 and shows no meaningful recovery; ... These findings identify Stage IV hospice access as an underrecognized national VHA quality priority warranting Stage IV—triggered automated palliative care consultation, embedded outpatient palliative care in oncology clinics, standardized referral protocols at documented progression, and veteran/family-facing hospice education. This analysis establishes a statistically rigorous national baseline for benchmarking interventions–and a call to action for the VHA oncology community to restore hospice as a core element of veteran-centered end-of-life care.

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Alzheimer’s blood test gets FDA clearance, but not CMS coverage

09/03/26 at 03:00 AM

Alzheimer’s blood test gets FDA clearance, but not CMS coverage Inside Health Policy, Washington, DC; by Jessica Karins; 9/2/26 A blood test aiming to help with early identification of Alzheimer’s disease, including in primary care settings, by detecting buildup in the brain of the key Alzheimer’s biomarker amyloid beta plague, has been cleared by FDA, but the test and others in its category are not yet covered by CMS or any Medicare Administrative Contractors, its developer confirmed, with MACs having to make an individual determination for each patient of whether payment for the test is appropriate.

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Priorities for advancing palliative care for Amyotrophic Lateral Sclerosis: a consensus report from a palliative care for ALS working group in the United States

09/02/26 at 03:00 AM

Priorities for advancing palliative care for Amyotrophic Lateral Sclerosis: a consensus report from a palliative care for ALS working group in the United States Muscle & Nerve; by Kara E. Bischoff, Yaowaree L. Leavell, Jessica M. Besbris, Christi Lero, Kelsey Noble, Astrid Grouls, Jerome Kurent, Benzi M. Kluger, Steven Z. Pantilat, Ambereen K. Mehta, on behalf of the International Neuropalliative Care Society's Palliative Care for ALS Working Group; 8/31/2026 The Palliative Care for ALS Working Group was formed within the International Neuropalliative Care Society, consisting of interprofessional ALS and palliative care clinicians, researchers, advocates, and patients and care partner representatives who are committed to improving palliative care for people living with ALS. The group engaged in a strategic planning process to determine what is needed to advance palliative care for people with ALS over the next 3–5 years. This report outlines the core recommendations from that strategic planning process. Recommendations are divided into five sections: (1) clinician education, (2) clinical service expansion, (3) research, (4) public awareness, and (5) policy change. Editor's Note: ALS is an especially devastating, demanding disease for patients, caregivers and families, for your clinical staff and volunteers. What disease-specific education and resources do you provide? How many ALS patients have your organization served in "x" years? Do you partner in any way with your regional ALS association? For non-clinical leaders, an important, easy distinction for you to remember the clinical, deeply personal differences between ALS versus ALZ: 

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