Literature Review

How to responsibly use AI in palliative care and hematologic malignancies CancerNetwork; podcast by Ram Prakash Thirugnanasambandam, MBBS; 2/2/26 In a conversation with CancerNetwork®, Ram Prakash Thirugnanasambandam, MBBS, discussed the evolving roles that artificial intelligence (AI)–based tools may play in palliative care and the management of different hematologic malignancies. ... According to Thirugnanasambandam, implementing AI into one’s workflow may help accurately predict disease subtypes and burdens among patients with leukemia, lymphoma, or multiple myeloma. ... Thirugnanasambandam also discussed some of the ethical considerations surrounding the growth of AI-based tools, highlighting information privacy concerns and potentially biased datasets as notable issues with these platforms. Although AI may assist with decision-making, Thirugnanasambandam stated that it ultimately cannot replace a human’s nuanced clinical judgment and empathy.

Concurrent care and equity: Addressing palliative care gaps for African American men in rural communities with a serious respiratory illnessAmerican Journal of Hospice & Palliative Medicine; by Cathy L. Campbell; 12/25Hospice and palliative care are often hard to access for African Americans (AA) living in rural areas with serious respiratory illnesses. Under the Medicare Hospice Benefit, patients must stop curative or life-sustaining treatments for their terminal illness, which limits options for concurrent care. This is a major challenge for AA men, whose average life expectancy is 67.8 years—about 10 years shorter than the national average. They also experience more care transitions in the last 6 months of life compared to White and Hispanic patients. These frequent transitions show how fragmented the health system is and how it often fails AA families. Using intersectionality and a vignette, this paper explores how overlapping factors—lived experience as AA man, rural location, and serious illness—affect access to palliative care.

[Australia] Cancer and dementia incidence are strongly correlated worldwide: Evidence from cross-national regression analysesFuture Science OA; by Wenpeng You, Brendon J Coventry, Maciej Henneberg; 12/25Cancer and dementia are two major health problems affecting millions of people around the world. Countries with higher cancer rates almost always have higher dementia rates. Even after we accounted for income, life expectancy, and other social factors, cancer remained one of the strongest predictors of dementia. These findings suggest that cancer and dementia share many of the same underlying causes, such as aging, chronic inflammation, lifestyle habits, and changes that come with economic development. Understanding these shared patterns can help countries plan for future healthcare needs.

Integrating psychiatric and hospice services: Legal and clinical considerations for involuntary commitment in multimorbid end-of-life care American Journal of Hospice and Palliative Medicine; by Ilana Marmershteyn, BS, Darian Peters, BS, Victor Milev, BS, Mario Jacomino, MD, MPH, and George Luck, MD, FAAHPM; 1/28/26  Multimorbid patients at the end-of-life face complex medical, psychosocial, and psychiatric challenges. Hospice care aims to address physical, emotional, and spiritual needs; however, psychiatric comorbidities, particularly acute crises, remain under-recognized and inconsistently managed. The intersection of psychiatric intervention, hospice care, and legal frameworks such as involuntary commitment presents significant clinical and ethical challenges.

Husband with Parkinson's was admitted into at-home hospice program and has dramatically improved. Have others experienced this? Aging Care; by Klwolf; 1/21/26 My DH has Parkinson’s that has been getting progressively worse for months. In early December we had him assessed for hospice and he was admitted. Since then, he’s improved dramatically. Has anyone else experienced dramatic improvement AFTER hospice enrollment? The hospice staff simply shrugs and says this sometimes happens and that we need to be prepared for him to revert back to his previous state. Editor's Note: Many clinicians have seen individuals improve after hospice enrollment, often due to better symptom control, reduced stress, or consistent interdisciplinary care. The concern here is not the improvement itself, but the hospice team’s reported response. A shrug can feel dismissive to families already living with uncertainty. How do we teach teams to communicate about improvement—honoring hope while preparing families with clarity, compassion, and trust?

A different kind of care: The compelling case for palliative care in advanced kidney disease docwirenews; by Keightley Amen; 1/20/26 Advanced kidney disease requires some of the most complex care in medicine due to medical management, comorbid conditions, symptom burden, patient and family psychosocial needs, difficult conversations, and advance care planning. Despite the significant coordination needed, care for this patient population is often more fragmented, with less access to supportive services, than for people with other chronic, life-limiting illnesses.

[Uganda] This hospice has a bold new mission: saving lives Alabama Public Radio / NPR; by Joanne Cavanaugh Simpson, Brian Simpson; 1/16/26 Deborah Nantenza learned about cervical cancer screening at a hospital in eastern Uganda, a rural region where early diagnosis is rare. ... The cancer screening, education and treatment were led by a hospice — an institution traditionally limited to easing the pain of the dying. The team at Rays of Hope Hospice Jinja in Uganda had long wanted to do more. Even with liquid morphine and other pain medications the hospice provided to ease symptoms, women with cervical cancer "didn't just die a normal death. They died after suffering, suffering," says Sylvia Nakami, executive director of the 20-year-old nonprofit.

Palliative care integration in oncology: A review and updateJournal of Hospice & Palliative Care; by Claire Wang, Thomas W LeBlanc; 12/25Palliative care (PC) is increasingly recognized as an essential component of high-quality cancer care, with evidence from randomized trials and meta-analyses demonstrating that it improves quality of life, mood, and goal-concordant end-of-life care. Despite these benefits, PC integration has been inconsistent, with many patients still receiving PC later in their disease course. Current models of integration include outpatient co-located PC clinics, inpatient consultation services, community- and home-based programs, and more recent innovations, such as telehealth and stepped approaches. Symptom control, coping support, longitudinal communication, and existential or spiritual interventions are among the active ingredients that are most consistently associated with improvements in patient outcomes. Implementation of precision PC requires embedding validated patient-reported outcomes and structured referral algorithms into oncology workflows, enabling real-time triage of targeted interventions.

Documentary sheds light on HIV patient’s science-advancing ‘last gift’ through UCSD study San Diego Union Tribune; by Noah Lyons; 12/30/25 The documentary "The Last Gift" follows Jim Dunn's end-of-life decision to donate his tissues to HIV research, highlighting the altruistic act of giving back to science. The film showcases Jim's journey and the impact of his final act on advancing HIV research. It is a poignant reminder of the power of individual generosity in the pursuit of medical breakthroughs. 

In their own words: Creating connections through narrative medicineJournal of Patient Experience; by Sneha Mantri, Lissa Kapust, Jillian Goober, David K Simon; 11/25People with Parkinson's disease (PwP) often report feeling unheard or hurried through clinical visits, without the opportunity to share their unique illness story. Simultaneously, clinicians report increasing dissatisfaction with efficiency pressures that disincentivize active listening and patient-centered communication. This research brief outlines a guided short-form journaling activity, the 55-word story, for PwP to share their stories in a format that can be received by busy clinicians. By the end of each cohort, nearly all (31/35 participants, 88.6%) reported an improved relationship with their neurologist, communication skills, clarity about goals and values, and/or increased community with other PwP. An online guided journaling activity was feasible, enjoyable, and successful at improving the well-being of PwP. This model can be used at other institutions or with other chronic illnesses.