The rise of psychedelic therapeutics for end-of-life care: A new frontier in mental health and palliative medicine

09/08/25 at 03:00 AM

The rise of psychedelic therapeutics for end-of-life care: A new frontier in mental health and palliative medicine 
AI Invest; by Julian Cruz; 9/3/25 
Aime Summary

  • Psilocybin therapy shows 35.15% anxiety reduction in end-of-life care trials, driving FDA Breakthrough Therapy designations and state-level regulatory reforms.
  • Canada's Quebec and U.S. states like Oregon/Colorado establish psilocybin access frameworks, with Oregon issuing 374 facilitator permits by 2025.
  • Psychedelics market valued at $7.4B in 2025 projects 15% CAGR to $22.6B by 2033, led by Cybin, Compass Pathways, and infrastructure providers like Psyence BioMed.
  • Patient advocacy groups secure policy wins (e.g., Oregon HB2387) while challenges persist in insurance coverage and practitioner training despite regulatory progress. 
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