Study examines biological causes of cancer deaths: Tumors invading large blood vessels may be to blame, UTSW researchers say

Study examines biological causes of cancer deaths: Tumors invading large blood vessels may be to blame, UTSW researchers say 
UT Southwestern Medical Center, Dallas, TX; by Newsroom; 10/16/25 
The ultimate cause of death from cancer may not be metastatic disease, as researchers have long surmised, but an infiltration of tumors into major blood vessels that cause blood clots and multiorgan failure, a one-of-a-kind clinical study led by UT Southwestern Medical Center suggests. These findings, published in Nature Medicine, could spur interventions that extend the lives of patients with advanced cancers.