Literature Review

$4.25 million gene therapy for kids becomes world's priciest drug NBC LEX18, by Alex Arger; 3/20/24 A lifesaving gene therapy for children born with a rare and debilitating disease has just been approved by the U.S. Food and Drug Administration. The catch? Its wholesale cost has been set at $4.25 million, making it the most expensive medicine in the world. Orchard Therapeutics announced the hefty price for Lenmeldy Wednesday, two days after the FDA approved the therapy as the only treatment for kids with metachromatic leukodystrophy, or MLD. 

Other Business Headlines of Interest, updated 3/21/24 per nasdaq.com

Never doubt that a small group of thoughtful, committed citizens can change the world. Indeed, it is the only thing that ever has. - Margaret Mead

Palliative care in the older adult with cancer and the role of the geriatrician: a narrative review Annals of Palliative Medicine, by Bibban Bant Deol, Lisa Binns-Emerick, MOhammad Kang, Pragnesh Patel; 3/15/24 online ahead of print Conclusions: Embedding primary care geriatrics in the palliative care arena helps to provide more access to this care. This integration helps providers address basic symptom management, advance care planning and work with individuals on goals of care to assure the care being provided is congruent individual's priorities. Older adults respond to symptoms different than their younger counterparts. Management of these symptoms has to be addressed in a manner commiserate with their age.

How home care providers build out successful training programs Home Health Care News, by Patrick Filbin; 3/19/24 Building a successful and sustainable caregiver training program in personal home care demands meticulous planning and execution. From defining leadership responsibilities to establishing a comprehensive training schedule, every aspect plays a pivotal role in shaping the program’s effectiveness. Strong training programs and ongoing education also go a long way in retaining caregivers in an industry where every provider is trying their best to hold onto the employees they onboard.

New ACO model paves way for innovative home-based primary care services: CMS McKnights Home Care, by Adam Healy; 3/20/24 The Centers for Medicare & Medicaid Services on Tuesday unveiled a new person-centered care payment model that expands how and where beneficiaries can receive primary care. “People whose primary care provider participates in the ACO PC Flex Model may get care in more convenient ways, like care based at home or through virtual means, extra help managing chronic diseases, and more preventive health services to keep them healthy,” CMS Administrator Chiquita Brooks-LaSure said in a statement. “Not only will people with Medicare receive more coordinated, seamless care that addresses their unique needs, but CMS is supporting primary care clinicians and giving them more flexibility to provide person-centered care.”

Medicare Advantage health equity factor to shake up ratings Modern Healthcare, by Nona Tepper; 3/20/24 A federal effort to promote health equity will redistribute billions of dollars in Medicare Advantage Star Ratings bonus payments among health insurance companies. Beginning in 2027, the Centers for Medicare and Medicaid Services will reward Medicare Advantage plans that demonstrate progress addressing health disparities. At the same time, the agency scrapped a bonus policy that benefited insurers that sustained high overall quality ratings over time. 

Planning for National Healthcare Decisions Day 2024: 8 ideas to spread the word the conversation project; 3/12/24 Looking for ideas to plan and promote NHDD in your community? We’ve pulled together some ideas from the hundreds of local, state, and national groups across the country who have shared what they did last year or are planning for this April 16th. Be sure to take a peek at this roadmap to help you navigate all things NHDD, including where to find more examples. We hope the information ... will spark ideas and get you started.

Multinational Association of Supportive Care in Cancer (MASCC) expert opinion/guidance on the use of clinically assisted hydration in patients with advanced cancer

Frailty needs to be a factor in drug development, proposed guidelines suggest McKnights Long-Term Care News, by Kristen Fischer; 3/20/24A new report on strategies for geriatric drug development and assessment determined that drugs need to consider age as well as other factors that older adults face such as cognitive impairment, frailty and polypharmacy. This is according to the International Union of Basic and Clinical Pharmacology (IUPHAR) Geriatric Committee, which published the report. The strategies specifically focused on integrating frailty as a factor in drug development. The report, published in the Journal of the American Geriatrics Society earlier this month, includes 12 principles pertaining to frailty in reference to drug development. The recommendations include measuring frailty at the start of when a person goes on a drug they’ll likely take regularly.

Fitch: Scrutiny of private equity deals is short-term positive Modern Healthcare, by Hayley Desilva; 3/18/24 Increased federal scrutiny of healthcare mergers and acquisitions is expected to have mixed consequences for providers' credit, particularly when private equity buyers are involved, according to Fitch Ratings. ... In December, the [Federal Trade Commission] FTC updated its merger guidelines to foster competition across all industries, including healthcare. However, healthcare acquisitions are expected to increase this year as financial conditions improve.

Hearing with Health and Human Services Secretary BecerraHouse Ways and Means CommitteePublisher's note: CA Representatives Steel (@ 4:01) and Van Duyne (@ 4:14) ask pointed questions of Secretary Becerra regarding hospice fraud, particuarly focused on Southern California. Thanks to Sheila Clark, California Hospice & Palliative Care Association, for sharing this link.

Give generative AI another decade to revolutionize healthcare Modern Healthcare - Opinion, by Keith Figoli; 3/15/24... Generative artificial intelligence is poised to transform healthcare by enabling solutions to effectively address [common patient care] challenges. This cutting-edge technology opens new avenues for innovation in diagnosis, treatment planning, operations efficiency and overall healthcare delivery–and industry leaders are taking notice. A recent survey revealed that 25% of healthcare organizations implemented a generative AI solution in 2023, while 58% plan to adopt one this year. However, the generative AI-driven transformation won’t – and shouldn’t – happen overnight.