Literature Review

Palliative care and quality outcomes in patients with brain metastases and poor prognosis: A multi-institutional analysis JCO Oncology Practice - An American Society of Clinical Oncology Journal; by Rohit Singh, MD, Camilo E. Fadul, MD, Emily Kopp, MS, Guneet Sarai, MD, Roger Anderson, PhD, Ryan F. Amidon, MD, Samantha Schuetz, MD, Amy Chang, MD, Ausia N. Iqbal, MD, Joseph A. Bovi, MD, and Alissa A. Thomas, MD; 2/23/26 Purpose: To analyze the patterns of palliative care (PC) consultation for patients with brain metastases (BMETs) and its association with treatment, overall survival (OS), and quality metrics (eg, advance directives [ADs], hospice enrollment). Conclusion: The involvement of PC services correlated with higher completion rates of ADs and increased hospice utilization, without compromising survival or significantly altering other treatment options. There is an unmet need for PC among patients with BMETs with poor prognosis.

Doing everything FOR the patient, not TO the patient HIStalk - Healthcare IT News & Opinion; by Nassib Charmoun; 2/23/26 “Do as much as possible for the patient and as little as possible to the patient.” That single sentence, written by Bernard Lown, MD in “The Lost Art of Healing,” should serve as a universal guide to thinking about medicine, caregiving, and what it truly means to heal. Dr. Lown was my mentor beginning in my early 20s and remained a close friend until his death in 2021 at age 99, He was decades ahead of his time. He believed that medicine should integrate scientific rigor with moral imagination, and that clinical excellence without compassion is incomplete care. ... Increasingly, the evidence suggests that quality of life, not simply quantity of life, must be the defining outcome.

Hospice use after ICU admission increased across the US from 2011–2023 Medical Xpress; by Boston University School of Medicine, edited by Gaby Clark; 2/19/26 ... In a new study from Boston University Chobanian & Avedisian School of Medicine, researchers have found that more older adults in the U.S. are being discharged to hospice after an ICU stay than in the past, and this increase happened even as overall short-term death rates stayed stable. This research is the first to quantify hospice use after ICU stays on a national scale, and suggests a real shift in how end-of-life care is delivered to the seriously ill. These findings appear online in the Annals of the American Thoracic Society.

[Japan] Effectiveness of music therapy combining life review and songwriting in patients with terminal cancer: A pilot study based on a mixed methods investigationBMC Palliative Care; by Nanami Nakaya, Ami Yamasato, Mayu Kondo, Shigeki Okino, Makoto Tokuhara, Banri Tsuda, Tetsuji Iida, Osamu Matsui, Koji Hino, Kenji Yamamoto; 1/26Spiritual well-being is a key protective factor against psychological distress in individuals receiving terminal cancer care, and several approaches have been proposed to enhance this aspect of care. In this study, we developed and evaluated the effectiveness of a novel intervention combining life review (a method known to improve spiritual well-being) with songwriting, a form of music therapy. Qualitative analysis of participants’ feedback yielded 77 codes, which were integrated into four major categories: (1) Positive feelings toward researchers or the music, (2) Recalling the past and realizing it was a good life, (3) Hope for the future, and (4) Sharing with others. The intervention significantly improved spiritual well-being, depression, and anxiety in individuals with terminal cancer.

Artificial intelligence-powered predictive tools to improve end-of-life decision-making: mini-review British Medical Journal (BMJ) Supportive & Palliative Care; by Abdullah Alabbasi, Muhanad Alzahrani, Faris Sultan and Mohammed Sayes; 2/18/26 Results: ... Preliminary qualitative work indicates that AI-generated summaries may assist communication among healthcare teams, though concerns persist regarding transparency, bias and over-reliance on algorithms. Conclusions: AI-driven prognostic models show promise in improving risk identification and facilitating earlier engagement with palliative care. Nonetheless, the current evidence base is preliminary. Future research should include prospective trials and strengthened ethical frameworks to ensure that the integration of AI-based prognostic tools into end-of-life decision-making is both safe and equitable. 

Cognitive decline is often linked to hearing loss: This may be whyMedicalNewsToday; by James McIntosh; 2/16/26

Comparison of patients seen by an embedded social worker and nurse practitioner palliative care model in hospital medicine versus referral-based specialty palliative care and their acute care utilization outcomes Journal of Palliative Medicine; by Laura P Gelfman, Li Zeng, Keisha Bergland, Elizabeth Rizzo, Cheyenne Higgins, Claire Doucette, Krishna Chokshi, Emily Chai; 2/17/26 Background: Hospitalized patients with serious illness often face delayed or limited access to palliative care. Embedded hospital primary palliative care (HPPC), led by social workers and nurse practitioners, may deliver more timely, needs-based support compared with referral-based specialty palliative care (SPC). Conclusions: An embedded SW/NP-led palliative care model in hospital medicine improves access, reduces acute care use, and is sustainable over time. This approach supports timely, culturally sensitive, needs-based palliative care and may be scalable for hospital-based delivery.

How to plan for a ‘good death,’ according to a VCU researcher VCU News, Virginia Commonwealth University; by Madeline Reinsel; 2/16/26 People talk a lot more about death than dying. That’s according to Yifan Lou, Ph.D., a Virginia Commonwealth University School of Social Work assistant professor who studies how expectations around death and end-of-life care differ across cultures. ... “My job is really trying to understand different populations and then help design a policy and health care system that can support their value of the good death.” Planning for a good death requires patients and families to make decisions around hospice care, pain management, quality of life, financial affairs and long-term care, ideally alongside a social worker.

What can we learn from death in the age of longevity? Time; by Arianna Huffington; 2/16/26 ... Research on those at the end of life shows that our values change as death approaches. At the end, we don’t crave more status or more things, but more connection. A study on terminally ill patients found that common reflections include concern for loved ones, gratitude, and spirituality. Another found that the most commonly discussed topics included accepting one's imperfections, celebrating and appreciating what you have, giving, and service to others. And a study of hospice patients found that they showed “the desire to grow and change at this critical time.” If hospice patients can grow and change at the end of life, why not grow and change now? ... It is a surprising, but important, lesson to learn: bringing death into our lives is what paradoxically allows us to live more fully.  

Palliative external beam radiation therapy for dysphagia in a 101-year-old man with esophageal adenocarcinomaCureus; by Pericles J. Ioannides, Jester M. Odrunia, Gina N. Perez, Morgan Butow, Georg A. Weidlich; 1/26Esophageal adenocarcinoma in centenarians is rare, and treatment options in this age group are limited. We present the case of a 101-year-old male patient with symptomatic distal gastroesophageal junction (GEJ) adenocarcinoma who presented with progressive dysphagia, aspiration, and weight loss. The patient underwent palliative external beam radiation therapy (EBRT) ... targeting the obstructive esophageal mass with a margin using volumetric-modulated arc therapy (VMAT) technique. The treatment was well tolerated by the patient with no significant acute toxicity. After treatment, the patient reported clinically meaningful improvement in functional status, with improved swallowing, advancing from liquids to a soft diet, weight gain, and improved QoL. Moderate-dose palliative radiation can be a safe and effective treatment in a centenarian with obstructive GEJ adenocarcinoma, particularly when endoscopic interventions are not successful or durable.

Hospice doctor shares what happens in the moments immediately after death Good; by Adam Albright Hanna; 2/3/26 Throughout human history, one question has bewildered every civilization, society, and individual. What happens after we die? For some people, it is a question for science. For others, it is a question of faith. But for Dr. B.J. Miller, it is a question that he is totally fine not knowing the answer to. Miller is a hospice and palliative care physician at the University of California, San Francisco. He is one of the world's leading voices on dignified death, and for him, the end of life is actually about the living. ... "I’ve been around people who are just about to die," Miller said. "Bodies that have just died. And there is this lingering sense, it’s true. There’s a feeling. It’s a palpable... yeah, there’s a lingering." ... "I didn’t need to have control over everything, I didn’t need to know the answers anymore. I mean, I love not knowing. The answer’s unimportant. It’s just a sacred and gorgeous moment."Editor's Note: Having served in direct hospice patient care from 1993–2002, I was present with many persons during their active dying and in the moments just after death, including attending deaths as a chaplain. Over time—and especially through the intimate experience of my parents’ deaths—that sense of sacredness Dr. Miller describes remains real for me. So I find myself wondering and asking non-clinical leaders: when you look at Average Daily Census (ADC), Length of Stay (LOS), and other familiar metrics, what do you see? Numbers on a spreadsheet? Or living measures of something immeasurably human—something that truly matters?

[Canada] The quiet web of care: Hospitals, hospice, paramedics and community working as one The Millstone; Mississippi Mills area, Canada; 1/25/26 When we think about care, most of us picture the hospital: rooms, nurses, doctors, the moment a life changes. But real care in North Lanark is not anchored to a single building. It’s a living web the Mississippi River Health Alliance — Almonte General Hospital, Carleton Place & District Memorial Hospital, Fairview Manor, and Lanark County Paramedic Service — working alongside Home Hospice North Lanark and Houle Healthcare so neighbors can get the right help at the right time, in the place that matters most. ... They are parts of the same journey, passing the baton back and forth so patients, families and neighbors are not left to navigate alone.Editor's Note: Pair this with today's post, "Why patient flow will decide hospital performance in 2026."

EV0034 Palliative pain relief: A case study of high-frequency spinal cord stimulation in an end-of-life cancer patientNeuromodulation: Technology at the Neural Interface; P. Majedi, Dominic Bailey; 1/26A significant proportion of patients with cancer will experience cancer-related pain at some point during their illness. The treatment approach for cancer-related pain is often multifaceted and may necessitate the use of advanced interventional methods, including spinal cord stimulation (SCS). Recent studies have demonstrated the utility and efficacy of SCS techniques in the treatment of cancer-related pain and chemotherapy induced neuropathy. Here, we present a case report on a patient receiving high frequency SCS at 10 kHz for end-stage cancer-related pain.