Literature Review

Odds for dementia nearly triple in the year after a strokeHealth Day, by Ernie Mundell; 2/1/24A person's odds for a dementia diagnosis nearly triple in the first year after a stroke, new research shows. This post-stroke spike in dementia risk does subside with time, but it never returns to pre-stroke levels, the same report found. "Our findings reinforce the importance of monitoring people with stroke for cognitive decline," said lead researcher Dr. Raed Joundi. 

Global cancer burden growing, amidst mounting need for services World Health Organization; 2/1/24Ahead of World Cancer Day, the World Health Organization (WHO)’s cancer agency, the International Agency for Research on Cancer (IARC), released the latest estimates of the global burden of cancer.  ... Three major cancer types in 2022: lung, breast and colorectal cancers

Nurses' encounters with patients having end-of-life dreams and visions in an acute care setting - A cross-sectional survey studyJ Adv Nurse, by Alison Hession, Tim Luckett, David Currow, Michael Barbato; 1/31/24Results: Fifty-seven nurses participated from a workforce of 169 (34% response rate), of whom 35 (61%) reported they had encountered end-of-life dreams and visions. The nature of end-of-life dreams and visions encountered was similar to those reported in previous studies by patients and clinicians. Nurses generally held positive attitudes towards end-of-life dreams and visions but identified an unmet need for education and training on this aspect of end-of-life care.Editor's Note: This research was in Australia, yet has global applications. For U.S. leaders, call on your chaplains, many of whom are trained pastoral counselors to sensitively support and explore patient's "dreams and visions," in non-manipulative ways.

Breakthroughs in Alzheimer's research give cause for optimismKiplinger, by Elaine Silvestrini; 1/29/24... Finding a cure or even an effective treatment has been difficult. Now, after billions of dollars in research and more than 100 drug failures, advocates are celebrating breakthroughs, including drugs that for the first time treat the underlying causes of the disease. Experts are optimistic that we may be on the precipice of significant changes in how the disease is treated and potentially even prevented. 

Cannabis for neurodegenerative disordersCannabis - Science and Technology, by Ruth Fisher; 1/30/24In this blog installment, we take a deep dive into research on how cannabis affects neurodegenerative disorders such as Alzheimer’s disease, multiple sclerosis, and Parkinson’s disease. ... The information presented in this section comes from the Cleveland Clinics, a nonprofit academic medical center.

Predictors of early hospice or death in patients with inoperable lung cancer treated with curative intentClin Lung Cancer, by Siddharth Ramanathan, Kimberly A Hochstedler, Anna M Laucis, Benjamin Movsas, Craig W Stevens, Larry L Kestin, Michael M Dominello, Inga S Grills, Martha Matuszak, James Hayman, Peter A Paximadis, Matthew J Schipper, Shruti Jolly, Thomas P Boike; Michigan Radiation Oncology Quality Consortium; NCBI published 1/31/24Introduction: Treatment for inoperable stage II to III non-small cell lung cancer (NSCLC) involves chemo-radiotherapy (CRT). However, some patients transition to hospice or die early during their treatment course. We present a model to prognosticate early poor outcomes in NSCLC patients treated with curative-intent CRT.

Anorexia Nervosa: Evaluating disparities in places of death in the United States over 22 years using the CDC WONDER databaseCureus / NCBI, by Nirmal Patel, Rahul Tyagi, Deepanwita Biswas, Ayesha Birjees, Chetana Rajesh 6, Sadia Khan; posted via NCBI 1/30/24Conclusions:[This] study found that death in home and hospice was more common than in medical or hospital nursing facilities in all four analyzed groups. These findings highlight the critical need for significant advancements in end-of-life care, particularly in home and hospice settings.

Criteria for enrollment of patients with COPD in palliative care trials: A systematic reviewJ Pain Symptom Manage, by Natalia Smirnova, Allison V Lange, Amanda Glickman, Kristen Desanto, Cara L McDermott , Donald R Sullivan, David B Bekelman, Dio Kavalieratos; 1/25/24Context: Use of palliative care interventions in chronic obstructive pulmonary disease (COPD) has increased in recent years and inclusion criteria used to identify patients with COPD appropriate for palliative care vary widely. We evaluated the inclusion criteria to identify ways to improve enrollment opportunities for patients with COPD.

Most US adults fail to recognize heart disease as leading killer of Americans, study findHCP Live, by Patrick Campbell; 1/24/24The American Heart Association's annual report on heart disease and stroke statistics for 2024 sheds new light on the impact and level of public education surrounding the impact of heart disease and stroke in the US and abroad.

Use of complementary health approaches overall and for pain management by US adultsJAMA, by Richard L. Nahin, MPH, PhD; Amber Rhee, MHS; Barbara Stussman, BA; 1/25/24Millions of US adults use complementary health approaches (CHAs) each year; ... Previously, the safety and efficacy of many of these approaches lacked rigorous clinical trials. Over the past 2 decades, increasing evidence has supported the safety and efficacy of selected approaches for pain management. We examined trends in CHA use among US adults at 3 time points: 2002, 2012, and 2022.

A study of how Americans die may improve their end of lifeMedical Xpress, by Rutgers University; 1/24/24A Rutgers Health analysis of millions of Medicare records has laid the groundwork for improving end-of-life care by demonstrating that nearly all older Americans follow one of nine trajectories in their last three years of life.

Timing of prognostic discussions in people with advanced cancer: a systematic reviewSupport Care Cancer, by Sharon H Nahm, Shalini Subramaniam, Martin R Stockler, Belinda E Kiely; 1/23/24Conclusions: Prognostic discussions with people with advanced cancer need to be individualised, and there are several key timepoints when doctors should attempt to initiate these conversations. These recommended timepoints can inform clinical trial design and communication training for doctors to help improve prognostic understanding.

New research challenges the commonly held view that opioids are the most powerful pain relieversSciTechDaily, by University of Sydney; 1/21/24A University of Sydney-led study challenges the prevailing view of opioids as the most effective pain relievers for cancer, revealing significant evidence gaps and suggesting NSAIDs as a potential alternative. This research advocates for more informed choices in cancer pain management, emphasizing patient empowerment and the consideration of non-opioid options.