Literature Review
Today's Encouragement
11/24/24 at 03:00 AMLearn from yesterday, live for today, and hope for tomorrow. The important thing is not to stop questioning. ~Albert Einstein
Sunday newsletters
11/24/24 at 03:00 AMSunday newsletters focus on headlines and top read stories of the last week (in order) - enjoy!
Today's Encouragement
11/23/24 at 03:55 AMThanksgiving Day is a good day to recommit our energies to giving thanks and just giving. ~Amy Grant
World Medical Association Declaration of Helsinki-Ethical principles for medical research involving human participants
11/23/24 at 03:50 AMWorld Medical Association Declaration of Helsinki-Ethical principles for medical research involving human participantsJAMA; World Medical Association; 10/24Preamble: The World Medical Association (WMA) has developed the Declaration of Helsinki as a statement of ethical principles for medical research involving human participants, including research using identifiable human material or data. The Declaration is intended to be read as a whole, and each of its constituent paragraphs should be applied with consideration of all other relevant paragraphs. While the Declaration is adopted by physicians, the WMA holds that these principles should be upheld by all individuals, teams, and organizations involved in medical research, as these principles are fundamental to respect for and protection of all research participants, including both patients and healthy volunteers.
Differences in drug shortages in the US and Canada
11/23/24 at 03:45 AMDifferences in drug shortages in the US and CanadaJAMA; Mina Tadrous, PharmD, PhD; Katherine Callaway Kim, MPH; Inmaculada Hernandez, PharmD, PhD; Scott D. Rothenberger, PhD; Joshua W. Devine, PharmD, PhD; Tina B. Hershey, JD, MPH; Lisa M. Maillart, PhD; Walid F. Gellad, MD, MPH; Katie J. Suda, PharmD, MS; 10/24There are persistent global drug shortages, in part because drug-related supply chains are increasingly globalized; these drug shortages are associated with delayed or missed treatment and adverse outcomes. In addition, pandemics and natural disasters disrupt global drug production, further affecting supply chains. [In this study] drug-related reports of supply chain issues were 40% less likely to result in meaningful drug shortages in Canada compared with the US. These findings highlight the need for international cooperation between countries to curb the effects of drug shortages and improve resiliency of the supply chain for drugs.
The Inflation Reduction Act and patient costs for drugs to treat heart failure
11/23/24 at 03:40 AMThe Inflation Reduction Act and patient costs for drugs to treat heart failureJAMA Network Open; Erin Trish, PhD; Karen Van Nuys, PhD; Joanne Wu, MS; Nihar R. Desai, MD, MPH; 10/24The 2022 Inflation Reduction Act (IRA) contains several provisions to lower Medicare drug costs, including permitting the Centers for Medicare & Medicaid Services (CMS) to limit the prices of certain medicines and altering the standard Part D benefit to limit patient out-of-pocket costs. CMS has set the prices of 10 drugs effective 2026, including 3 commonly prescribed as part of combination therapy for heart failure (HF): dapagliflozin, empagliflozin, and sacubitril/valsartan. Dapagliflozin and empagliflozin also treat other conditions, including diabetes and chronic kidney disease. In this cross-sectional study of Medicare beneficiary costs ... benefit redesign eliminates the coverage gap in 2025, and caps annual out-of-pocket expenditures, [and] ... will reduce and smooth patient out-of-pocket burden.
Health professions students’ reflections about principles of interprofessional collaboration after shadowing interprofessional palliative care rounds
11/23/24 at 03:35 AMHealth professions students’ reflections about principles of interprofessional collaboration after shadowing interprofessional palliative care roundsAmerican Journal of Hospice and Palliative Medicine; Jeannette Kates, PhD, APRN, FPCN; Ceasia Brown, BA; Jenna Campolieto, BA; Maria Brucato, PhD; 10/24Future healthcare professionals are educated on collaborative practice methods through interventions that may include shadowing. While shadowing allows students to learn from and about other health professions, it often fails to offer an opportunity for the student to work and collaborate with other health professionals. These results suggest that shadowing offers an opportunity to identify and learn interprofessional competencies in interprofessional palliative care curricula, as made evident through student reflection assignments.
Dialysis facility staffing ratios and kidney transplant access among adolescents and young adults
11/23/24 at 03:30 AMDialysis facility staffing ratios and kidney transplant access among adolescents and young adultsJAMA; Alexandra C. Bicki, MD, MPH; Barbara Grimes, PhD; Charles E. McCulloch, PhD; Timothy P. Copeland, MPP, PhD; Elaine Ku, MD, MAS; 10/24In this study of adolescents and young adults treated at US dialysis facilities, patients at facilities with higher patient to staff ratios had lower incidence of waitlisting and kidney transplant compared with those receiving care at facilities with lower patient to staff ratios. The effect size for the incidence of transplant was similar with respect to both patient to nurse and patient to social worker staffing ratios, but patient to nurse ratio was not statistically significantly associated with the incidence of waitlisting.
Willingness to be present throughout patient death via medical aid in dying in a national sample of interdisciplinary US hospice clinicians: a content analysis of rationales
11/23/24 at 03:25 AMWillingness to be present throughout patient death via medical aid in dying in a national sample of interdisciplinary US hospice clinicians: a content analysis of rationalesPalliative Care and Social Practice; Todd D. Becker, Cindy L. Cain, John G. Cagle, Joan K. Davitt, Nancy Kusmaul, Paul Sacco; 10/24 The United States is one of a growing number of countries across Europe, North America, Oceania, and South America to have legalized what, domestically, is referred to as medical aid in dying (MAID). The objective of the current study was to explore attitudes toward presence throughout a patient’s death via MAID in hospice physicians, nurses, social workers, and chaplains. Participants who were willing to be present (n = 305 [74%]) attributed their willingness to personal support, definitions of quality clinical care, and values from their professional training. Those who were unwilling (n = 63 [15%]) noted personal objections to the concept of MAID, personal objections to MAID participation, and perceptions of MAID’s misalignment with healthcare. Hospice clinicians would benefit from greater professional guidance and support pertaining to MAID.
Suicide deaths among adolescent and young adult patients with cancer
11/23/24 at 03:20 AMSuicide deaths among adolescent and young adult patients with cancerJAMA Network Open; Koji Matsuo, MD, PhD; Christina J. Duval, BA; Briana A. Nanton, BS; Jennifer A. Yao, BA; Erin Yu, BS; Christian Pino, MD; Jason D. Wright, MD; 11/24The overall cancer incidence among adolescent and young adult (AYA) patients is increasing at an alarming rate in the US largely driven by thyroid cancer. Although cancer mortality continues to decrease among AYA patients, those who survive cancer are at elevated risk for emotional distress, mental health problems, and suicide. Together with the population-level increase in the US suicide death rate, the results of this assessment call for attention focused on the increasing suicide death rate among AYA patients with cancer, particularly male individuals. The proportion of AYA patients with cancer of thyroid, testis, or cutaneous melanoma who had a suicide death was greater than 2%, and they most benefit from a psychosocial and mental health evaluation. Because this study noted that many suicide deaths among these AYA patients with cancer occur years after the cancer diagnosis, long-term care and support for cancer survivors is recommended.
Facility- and community-level factors associated with hospice patient experience
11/23/24 at 03:15 AMFacility- and community-level factors associated with hospice patient experiencePalliative and Supportive Care; by Mengying He, Ganisher Davlyatov, Gregory Orewa, Haiyan Qu, Robert Weech-Maldonado; 11/24For-profit and chain-affiliated hospices were negatively associated with CAHPS® scores. Organizational longevity and Medicare payer mix were positively associated with CAHPS® scores. Hospice community factors including competition, per capita income, and the racial/ethnic minorities' percentage were negatively associated with CAHPS® scores.
Economic value of unpaid family caregiver time following hospital discharge and at end of life
11/23/24 at 03:10 AMEconomic value of unpaid family caregiver time following hospital discharge and at end of lifeJournal of Pain and Symptom Management; by Brystana G Kaufman, Wenhan Zhang, Sahar Shibeika, Ro W Huang, Ting Xu, Cory Ingram, Allison M Gustavson, Diane E Holland, Catherine Vanderboom, Courtney H Van Houtven, Joan M Griffin; 12/24Results: Of 282 Family caregivers, 94% were non-Hispanic White, 71% were female, 71% had a college degree, and 51% were in the workforce. Family caregivers of decedents (58%) compared to survivors reported significantly more caregiving hours per person-month (392 vs. 272), resulting in higher estimated economic value per person-month using opportunity ($12,653 vs. $8843), proxy ($5689 vs. $3955), and combined costing methods ($9490 vs. $6443). Conclusion: This study informs more complete economic evaluations of palliative care by estimating the economic value of unpaid caregiving. The high intensity of unpaid caregiving for people with serious illness, especially toward the end of life, should be considered when designing policies and interventions to support family caregivers. Better methods for approximating economic value are needed to address potential inequities in current valuation approaches.
Artificial intelligence and machine learning in cancer pain: A systematic review
11/23/24 at 03:05 AMArtificial intelligence and machine learning in cancer pain: A systematic reviewJournal of Pain and Symptom Management; by Vivian Salama, Brandon Godinich, Yimin Geng, Laia Humbert-Vidan, Laura Maule, Kareem A Wahid, Mohamed A Naser, Renjie He, Abdallah S R Mohamed, Clifton D Fuller, Amy C Moreno; 12/24Forty four studies from 2006 to 2023 were included. Implementation of AI/ML tools promises significant advances in the classification, risk stratification, and management decisions for cancer pain. Further research focusing on quality improvement, model calibration, rigorous external clinical validation in real healthcare settings is imperative for ensuring its practical and reliable application in clinical practice.
[Australia] Components of home-based palliative and supportive care for adults with heart failure: A scoping review
11/23/24 at 03:05 AM[Australia] Components of home-based palliative and supportive care for adults with heart failure: A scoping reviewPalliative Medicine; Madhurangi Perera, Ureni Halahakone, Sameera Senanayake, Sanjeewa Kularatna, William Parsonage, Patsy Yates, Gursharan K. Singh; 10/24Palliative care and supportive care provided in the home for people with heart failure can improve quality of life, caregiver wellbeing and reduce healthcare costs. Ensuring patient and caregiver-centred care supported by a multidisciplinary team is essential to delivering home-based palliative and supportive care for people with heart failure. Further research focussed on the role of digital interventions in home-based palliative and supportive care, the composition of the multidisciplinary team and research which includes individuals across all stages of heart failure is needed.
Saturday newsletters
11/23/24 at 03:00 AMSaturday newsletters focus on headlines and research - enjoy!
Machine learning for targeted advance care planning in cancer patients: A quality improvement study
11/23/24 at 03:00 AMMachine learning for targeted advance care planning in cancer patients: A quality improvement studyJournal of Pain and Symptom Management; by Mihir N Patel, Alexandria Mara, Yvonne Acker, Jamie Gollon, Noppon Setji, Jonathan Walter, Steven Wolf, S Yousuf Zafar, Suresh Balu, Michael Gao, Mark Sendak, David Casarett, Thomas W LeBlanc, Jessica Ma; 12/24Objectives: Examine a quality improvement mortality prediction algorithm intervention's impact on ACP documentation and EOL care. Conclusion: Identifying patients with cancer and high mortality risk via machine learning elicited a substantial increase in documented ACP conversations but did not impact EOL care. Our intervention showed promise in changing clinician behavior. Further integration of this model in clinical practice is ongoing.
[Canada] Feasibility of prospective error reporting in home palliative care: A mixed methods study
11/23/24 at 03:00 AM[Canada] Feasibility of prospective error reporting in home palliative care: A mixed methods studyPalliative Medicine; Allison M Kurahashi, Grace Kim, Natalie Parry, Vivian Hung, Bhadra Lokuge, Russell Goldman, Mark Bernstein; 10/24 Palliative care patients may be particularly vulnerable to experiencing errors due to the complex communication among interdisciplinary team members (including the patient and their caregivers), the use of high-risk medications such as opioids and benzodiazepines, polypharmacy, patient frailty, and patient cognitive decline. Care in patients’ homes presents additional challenges to patient care that are unique from hospital settings: Decreased communication about roles and responsibilities in care can result from involvement of multiple care teams and different electronic records. The collaborative nature of care in a home-based palliative care context may present unique challenges to translating error reporting to improved patient safety. Physicians are amenable to error reporting activities so long as data is used to improve patient safety.
My top 10 list for living with cancer
11/22/24 at 03:10 AMMy top 10 list for living with cancer Cure; by Kelly Irvin; 11/19/24 I’m coming up on the ninth anniversary after my diagnosis of stage 4 ovarian cancer in January 2016. As always, this causes me to ponder my life as someone living with cancer for the rest of my life. I ponder why I’m still here and others are not. Have I used this time well? What have I learned that might be of use for other “lifers,” as well as those just starting on this journey? It’s that last question I’m focused on here. The following is my top 10 list for living with cancer when there’s no likelihood of hearing those magical words “cancer-free.”
This New York Times bestselling author cracked the code on transformative leadership
11/22/24 at 03:00 AMThis New York Times bestselling author cracked the code on transformative leadership Forbes Talks; by Brittany Lewis with Keith Ferrazzi; 11/19/24 Keith Ferrazzi and Forbes reporter Brittany Lewis discuss his new book Never Lead Alone: 10 Shifts from Leadership to Teamship on 'Forbes Talks.' Keith Ferrazzi, a #1 New York Times Bestselling Author of Never Eat Alone, Leading Without Authority, Competing in the New World of Work, and his newest book, Never Lead Alone: 10 Shifts from Leadership to Teamship. Keith is an acclaimed global executive team coach, who stands at the forefront of transformative leadership having coached the transformation of Fortune 500 corporations, the World Bank, fast growth Unicorns and even governments of entire countries. The founder of Ferrazzi Greenlight, Keith spearheads behavioral shifts in leadership and high impact teams, empowering organizations to thrive in the ever-evolving landscape of business. Keith's research can be found in prestigious publications including Harvard Business Review, Forbes, The Wall Street Journal, Fortune, Fast Company, and Inc. Magazine, where his columns serve as valuable insights for business leaders.
The work of hospicing
11/22/24 at 03:00 AMThe work of hospicing Stanford Social Innovation Review; by Vanessa Andreotti and Habib Nabatu; Winter 2025 issue, 11/20/24As we stand at the precipice of endings—of species, ecosystems, organizations, and systems themselves—the work of hospicing is to move beyond fear and embrace the deep transitions ahead with wisdom. To be stewards of this time, we must develop the practices and capacities to tend to these endings, not with urgency or control, but with a kind of stillness that invites the birth of new ways of being. Endings are not failures; they are part of a cycle that requires presence, reverence, and humility. Our hyperfocus on growth and expansion has left us ill-prepared to sit with death—whether it be the death of industries or the biosphere—and this discomfort with grief prevents us from being fully alive in the present. How might we allow the crumbling of outdated structures without rushing to rebuild too quickly? How might we hold space for what is irreversibly changing, without rushing to save or fix it? ...
Nursing homes with more black residents lag in care goal discussions
11/22/24 at 03:00 AMNursing homes with more black residents lag in care goal discussions Medical Xpress; by Columbia University Irving Medical Center; 11/20/24 New research from Columbia University School of Nursing published in the American Journal of Hospice and Palliative Medicine shows that timely goals of care discussions are less likely to take place in nursing homes with a higher percentage of Black residents. These discussions are crucial to ensuring that nursing home residents receive care that aligns with their wishes, postdoctoral research fellow Jung A. "Chloe" Kang, Ph.D. '24, Professor Patricia Stone, Ph.D., and their colleagues note in the report, published online September 15, 2024. But these conversations are often delayed until patients experience life-threatening events, the authors add, which can lead to unwanted therapies and unnecessary hospitalizations. ...
Today's Encouragement: We must find time to stop and thank the people who ...
11/22/24 at 03:00 AMWe must find time to stop and thank the people who make a difference in our lives. ~ John F. Kennedy Editor's note: Today marks the 61st anniversary of his death, November 22, 1963. As we know too well in our end-of-life roles, death's timing often does not give us time to voice what matters most to those persons who matter most. May we all "find time to stop and thank" persons who "make a difference in our lives"--whether over the course of a lifetime or in a simple spontaneous moment.
Q&A: Prioritizing health equity with Emory Healthcare’s Chief Transformation Officer
11/22/24 at 03:00 AMQ&A: Prioritizing health equity with Emory Healthcare’s Chief Transformation Office CDW Healthcare - Patient-Centered Care; by Teta Alim; 11/19/24 Most healthcare organizations regularly prioritize goals to improve the patient experience and increase clinician satisfaction, aligning with the Quintuple Aim. Atlanta-based Emory Healthcare created the role of chief transformation officer to focus on these areas, and in July 2023, Dr. Amaka Eneanya became the first to fill the role. ... What would you say were the top three lessons you learned during the first year in your new role? ENEANYA: It's been a great year. For lesson one, as someone coming from a different part of the U.S., ingraining yourself and getting to know the people and the culture of the organization that you’re in, that’s important to determine the change readiness of an organization. ... The second lesson is that change is exciting. There's a lot of trepidation with change, and part of being effective with change management and transformation is really garnering excitement. ... The third lesson that continues to be pervasive in my career is that health equity is poorly understood. ... You have to start with the basic foundation and concepts of health equity before you can make initiatives, otherwise people won't understand what you're doing, and they might have a visceral response to what you're doing because of the misinformation around health equity.
Generations of legacy: The Meyer family returns for 21st Annual Hospice Golf Tournament
11/22/24 at 03:00 AMGenerations of legacy: The Meyer family returns for 21st Annual Hospice Golf Tournament Advent Health Palm Coast; by Michelle Bartlome; 11/21/24 The 21st annual Stuart F. Meyer Hospice House golf tournament on Oct. 23 was a celebration of community support and a touching tribute to the enduring legacy of Stuart F. Meyer. Among the 144 players was one of Meyer’s grandsons, Bryan Ashley, 34, of Fenton, Missouri. He, along with his cousins and brother-in-law, represented his family and honored his grandfather’s memory at the event. ... Stuart F. Meyer, former president of the St. Louis Cardinals and Flagler County resident, spent his final days in the compassionate care of hospice. In his memory, his family supported the construction of a hospice house on the AdventHealth Palm Coast campus more than two decades ago. ... This year’s Stuart F. Meyer Hospice House Golf Tournament raised $56,000, with 36 golf teams signed up.
YoloCares: The case for independence
11/22/24 at 03:00 AMYoloCares: The case for independenceThe Davis Enterprise; by Craig Dresang; 11/17/24I recently received an email from an individual in Temple Terrace, Fla., informing me that two Northern California nonprofit hospices — with close historical ties to YoloCares — have decided, via affiliation, to turn their keys over to a Florida-based health system that has had no previous presence in California.Publisher's note: Craig Dresang, CEO of YoloCares, goes on to discuss questions and concerns with Chapters Health System's (Tampa, FL) acquisition of Hospice of East Bay (Pleasant Hill, CA), Hospice of Santa Cruz County (Scotts Valley, CA), Nathan Adelson Hospice (Las Vegas, NV), and Willamette Vital Health (Salem, OR). The original story - Chapters Health System launches new Chapters Health West Division - was announced 10/30/24.