Literature Review
Antibiotics at end of life: Where are we now and where are we going? A narrative review
07/05/25 at 03:30 AMAntibiotics at end of life: Where are we now and where are we going? A narrative reviewAmerican Journal of Hospice and Palliative Medicine; by Patrick D Crowley, Francis X Whalen, Leslie R Siegel, Douglas W Challener; 8/25Antibiotics are frequently prescribed at the end of life, though the benefits and harms are not well understood. Prescribing practices vary based on individual situation and geographic location. Patients with cancer and those hospitalized receive more antibiotics than those enrolled in outpatient hospice. Urinary tract infections and pulmonary infections are the most common conditions treated with antibiotics at the end of life -most often with penicillin derivatives and vancomycin in the hospital, fluoroquinolones in outpatient, and cephalosporins in both settings. When asked, patients most often prefer limiting antibiotics to symptom management at the end of life. Physicians’ over-estimation of patient preference for antibiotics and the increased probability of misdiagnosis increases antibiotic prescription rates. Antibiotics can improve symptoms when used for specific diseases at the cost of drug reactions, resistant organisms, and delayed discharge. Antibiotic use has variable results on survival duration.
Clinicians’ perceptions about institutional factors in moral distress related to potentially nonbeneficial treatments
07/05/25 at 03:25 AMClinicians’ perceptions about institutional factors in moral distress related to potentially nonbeneficial treatmentsJAMA Network Open; Teva D. Brender, MD; Julia K. Axelrod, BA; Sofia Weiss Goitiandia, MA, MSc; Jason N. Batten, MD, MA; Elizabeth W. Dzeng, MD, PhD, MPH; 6/25In this qualitative study, we described institutional factors that may exacerbate, prevent, or mitigate the influence of societal factors contributing to moral distress related to potentially nonbeneficial LST [life-sustaining treatments]. Health systems should consider how health care consumerism influences patients’, families’, and clinicians’ expectations regarding potentially nonbeneficial LST, particularly at hospitals with advanced technological interventions (eg, organ transplantation, extracorporeal membrane oxygenation, salvage chemotherapies). Future studies should explore the societal and institutional factors contributing to moral distress for clinicians at lower-resourced hospitals, such as inaccessible advanced treatments and barriers to transferring patients for higher levels of care. While some institutions lacked sufficient structures to support clinicians’ efforts to de-escalate potentially nonbeneficial treatments, policies empowering clinicians across the medical hierarchy, as well as conflict resolution and emotional support resources (eg, palliative care) might prevent or mitigate moral distress.
Palliative care knowledge, attitudes, and self-competence of nurses working in hospital settings
07/05/25 at 03:20 AMPalliative care knowledge, attitudes, and self-competence of nurses working in hospital settingsJournal of Palliative Care; Mona Ibrahim Hebeshy, PhD, RN; Darcy Copeland, PhD, RN; 6/25With the growing need to integrate palliative care into healthcare systems, nurses in hospital settings often provide care for patients with life-limiting conditions, many of whom lack formal education in palliative care. [Conclusions:] Nurses generally feel competent; however, they often lack confidence in addressing patients’ social and spiritual needs. They experienced unease when discussing death and exhibited paternalistic attitudes. Significant differences were found in educational background, nursing experience, personal caregiving experience, and practice setting. Positive correlations exist between attitudes, knowledge, and self-competence, indicating that greater knowledge and competence were associated with better attitudes toward end-of-life care.
Top ten tips palliative care clinicians should know about managing diabetes at end-of-life
07/05/25 at 03:15 AMTop ten tips palliative care clinicians should know about managing diabetes at end-of-lifeJournal of Palliative Medicine; by Rebekka DePew, Tonya Hershman, Monica Giles, William E Rosa, Kimberly Curseen; 6/25Palliative care clinicians will regularly take care of patients with diabetes and play numerous roles in educating not only patients but also families and care partners regarding the changing balance of harms and benefits of blood glucose control as patients near end of life (EOL). There is limited evidence regarding the optimal timing and process for de-escalation of blood sugar monitoring and diabetes medications (including insulin) in the hospice and EOL setting.
Fireproofing the soul: Navigating fear of the afterlife among palliative care patients
07/05/25 at 03:10 AMFireproofing the soul: Navigating fear of the afterlife among palliative care patientsJournal of Palliative Medicine; Ptr Shannon Blower, Jonathan Walker, Lucius Walker, Steven Radwany; 6/25Among palliative care patients, spiritual uncertainty about what may await them after death is a fairly common but often overlooked source of anxiety. Specifically, patients (especially those from orthodox Christian backgrounds that propound the concept of hell as a literal place) may harbor unexpressed fears about being consigned to hell due to the perceived sins they have committed in life. Such fears can be genuinely debilitating and may result in non-responsiveness to traditional palliative therapy. Here, we discuss our experiences with this phenomenon and propose some possible solutions. We offer readers suggestions for how to best identify potential sufferers, broach the subject with such patients, and reassure them.
Palliative care in the ICU: From oxymoron to standard of care
07/05/25 at 03:05 AMPalliative care in the ICU: From oxymoron to standard of careIntensive Care Medicine; Nancy Kentish-Barnes, Judith E. Nelson; 6/25 Palliative care can be integrated into intensive care through ICU clinicians and palliative care specialists, and these approaches are complementary and synergistic. One study found that proactive specialist involvement in ICU rounds for high-risk patients led to more and earlier family meetings and shorter hospital stays. However, collaboration challenges, such as continuity of communication, highlight the need for close team cooperation. The integrative model trains intensivists and ICU nurses to embed palliative care into routine practice, ideally starting in medical and nursing education. Research has shown that improved communication and support from intensivists and ICU nurses are associated with better bereavement outcomes for families, including reduced post-traumatic stress, anxiety, depression, and prolonged grief.
[Spain] “The good death”: Experience of parents who have suffered the loss of a child in a pediatric intensive care unit. A phenomenological study
07/05/25 at 03:05 AM[Spain] “The good death”: Experience of parents who have suffered the loss of a child in a pediatric intensive care unit. A phenomenological studyJournal of Pediatric Nursing; by Sara Alcón-Nájera, Rosa Blanca Ortiz-Pizarro, Elena Peña-Meléndez, Alberto Sánchez-Gallego, María Teresa González-GilThe ‘good death’ condenses experiences of parents into a constructive interpretation. It is characterised by the fact that it is participated, accompanied and honoured. It requires exquisite holistic care (emotional/social/relational and spiritual). It promotes a family-centered approach and emotional wellbeing of parents. The family's perception of a ‘good death’ is a powerful facilitator of bereavement. The experience of the death of a child in a Pediatric Intensive Care Unit must ensure a peaceful, dignified, and respectful death, accompanied and participated in by the family to achieve a “Good Death”. Evidence-based palliative and end-of-life care is essential for developing protocols and resources that ensure excellent support for families and their adaptation to the loss.
[Italy] Palliative Performance Scale predicts mortality in cardiac intensive care unit
07/05/25 at 03:00 AM[Italy] Palliative Performance Scale predicts mortality in cardiac intensive care unitOpen Heart; by Laura Sofia Cardelli, Lorenzo Gamberini, Beatrice Dal Passo, Silvia Zagnoni, Francesca Sciarra, Federica Frascaro, Alice Vitagliano, Valeria Carinci, Maria Laura Canale, Gianni Casella; 6/25Patients with PPS ≤70 had significantly higher 1-year all-cause mortality and in-hospital all-cause mortality. The PPS is a reliable and independent predictor of mortality in CICU patients. Incorporating PPS into clinical practice may enhance risk stratification, guide decision-making and optimise resource allocation in this high-risk population.
Saturday newsletters
07/05/25 at 03:00 AMSaturday newsletters focus on headlines and research - enjoy!
Medicare Advantage plan disenrollment: Beneficiaries cite access, cost, and quality among reasons for leaving
07/05/25 at 03:00 AMMedicare Advantage plan disenrollment: Beneficiaries cite access, cost, and quality among reasons for leavingHealth Affairs; by Geoffrey J. Hoffman, Lianlian Lei, Ishrat Alam, Myra Kim, Lillian Min, Zhaohui Fan, Deborah Levine; 6/25Medicare Advantage (MA) is growing in popularity, but it is seeing substantial plan disenrollments among high-risk Medicare beneficiaries. Understanding and addressing factors associated with disenrollment are crucial for improving MA access and quality but are complicated by data issues, including the inability to adequately assess beneficiaries’ perceptions of access and quality in MA... Difficulty accessing needed medical care was more strongly associated with MA-to–traditional Medicare exits than MA-to-MA plan switching. Dissatisfaction with access, cost, and quality was much more common for enrollees in poor health. These findings renew concerns about access to high-quality care for high-risk and other MA enrollees.
America the Beautiful ~ lyrics by Katharine Lee Bates, sung by Ray Charles
07/04/25 at 03:45 AMAmerica the Beautiful ~ lyrics by Katherine Lee Bates, with its historyAs sung by Ray Charles
The ultimate measure of a man is not where he stands in moments of comfort and convenience, but ...
07/04/25 at 03:40 AMThe ultimate measure of a man is not where he stands in moments of comfort and convenience, but where he stands at times of challenge and controversy. ~ Martin Luther King, Jr.
In America, nobody says you have to ...
07/04/25 at 03:05 AMIn America, nobody says you have to keep the circumstances somebody else gives you. ~ Amy Tan, “The Joy Luck Club”
May we think of freedom, not as the right to do as we please, but as ...
07/04/25 at 03:00 AMMay we think of freedom, not as the right to do as we please, but as the opportunity to do what is right. ~ Peter Marshall
The Earth and myself are of one mind. Perhaps you think ... If I thought you were sent by the Creator ...
07/04/25 at 03:00 AMThe Earth and myself are of one mind. Perhaps you think the Creator sent you here to dispose of us as you see fit. If I thought you were sent by the Creator I might be induced to think you had a right to dispose of me. ~ Chief Joseph, Nez Perce Tribe
I guess we all like to be recognized not for one piece of fireworks but for ...
07/04/25 at 03:00 AMI guess we all like to be recognized not for one piece of fireworks but for the ledger of our daily work. ~ Neil Armstrong
The happiness of America is intimately connected with ...
07/04/25 at 03:00 AMThe happiness of America is intimately connected with the happiness of all mankind; she is destined to become the safe and venerable asylum of virtue, of honesty, of tolerance, and quality and of peaceful liberty. ~ Marquis de Lafayette
True heroism is remarkably ...
07/04/25 at 02:50 AMTrue heroism is remarkably sober, very undramatic. It is not the urge to surpass all others at whatever cost, but the urge to serve others at whatever cost. ~ Arthur Ashe
All great change in America begins at ...
07/04/25 at 02:40 AMAll great change in America begins at the dinner table. ~ Ronald Reagan
Where, after all, do universal human rights begin? ...
07/04/25 at 02:35 AMWith freedom comes responsibility. ~ Eleanor Roosevelt
I had no idea that history was being made. I was just ...
07/04/25 at 02:30 AMI had no idea that history was being made. I was just tired of giving up. ~ Rosa Parks
Those who deny freedom to others ...
07/04/25 at 02:20 AMThose who deny freedom to others deserve it not for themselves. ~ Abraham Lincoln
Remember, remember always, that all of us, and you and I especially, are ...
07/04/25 at 02:10 AMRemember, remember always, that all of us, and you and I especially, are descended from immigrants and revolutionists. ~ Franklin D. Roosevelt
America, you great unfinished symphony, you sent for me. ...
07/04/25 at 02:00 AMAmerica, you great unfinished symphony, you sent for me. You let me make a difference. A place where even orphan immigrants can leave their fingerprints and rise up. ~ Lin Manuel Miranda, as Alexander Hamilton, in Broadway's 2014 Hamilton
We hold these truths to be self-evident ...
07/04/25 at 01:15 AMWe hold these truths to be self-evident, that all men are created equal, that they are endowed by their Creator, with certain unalienable Rights, that among these are Life, Liberty and the pursuit of Happiness. ~ The Declaration of Independence, 1776